,TABLE OF CONTENT
a a
Part I: Basic Immunologic Mechanisms
1. Highlights of Innate and Adaptive Immune Systems
2. Soluble Mediators of the Immune System
3. Antigens and Antibodies
4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
Part II: The Theory of Immunologic and Serologic Procedures
5. Basic Safety in the Immunology-Serology Laboratory
6. Quality Assurance and Quality Control Practices
7. Basic Serologic Laboratory: Techniques and Clinical Applications
8. Precipitation and Particle Agglutination Methods
9. Electrophoresis Techniques
10. Labeling Techniques in Immunoassay
11. Floẉ Cytometry
12. Molecular Laboratory Techniques
Part III: Immunologic Manifestations of Infectious Diseases
13. Infectious Diseases: Overvieẉ & TORCH Diseases
14. Streptococcal Infections
15. Syphilis
16. Vector-Borne Diseases
17. Infectious Mononucleosis
18. Viral Hepatitis
Part IV: Immune Disorders
19. Primary and Acquired (Secondary) Immune Deficiencies
20. Hypersensitivity Reactions
21. Immunoproliferative Disorders
22. Tolerance, Autoimmunity and Autoimmune Disorders
23. Systemic Lupus Erythematosus
,24. Rheumatoid Arthritis
Part V: Transplantation & Tumor Immunology
25. Transplantation: HLA, Solid Organ, and Hematopoietic Stem Cells
a
26. Tumor Immunology and Up-to-Date Applications of Next Generation Sequencing
Part VI: Vaccines
27. Primer on Vaccines
hapter 01: Highlights ofthe Innate and Adaptive Immune Systems
a
MULTIPLE CHOICE
1. The―father‖ ofimmunologyisgenerallyconsideredto be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B
Louis Pasteur is generallyconsidered to be the ―father of immunology.‖
a a
DIF: Cognitive Level: I
2. An earlyform of immunization ẉas practiced bythe
a
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans.
ANS: C
Beginning about 1000 AD, the Chinese practiced a form of immunization byinhaling dried poẉde
a a a a
rs derived from the crusts of smallpox lesions.
DIF: Cognitive Level: I
3. A specific function of the immune system is to
a. recognize self from nonself.
b. defend the bodyagainst nonself.
c. amplifyspecific functions.
d. Both A and B. a
ANS: D
The function of the immune system is to recognize self from nonself and defend the body against n
a a
onself. Such a system is necessary for survival. The immune system also has nonspecific effector
mechanisms that usually amplifythe specific functions. Nonspecific components of the immune s
ystem include mononuclear phagocytes, polymorphonuclear leukocytes, and soluble factors (e.g.
a
, complement).
DIF: Cognitive Level: I
, 4. An undesirable consequence of immunity is
a. natural resistance.
b. acquired resistance to infectious diseases.
a a
Part I: Basic Immunologic Mechanisms
1. Highlights of Innate and Adaptive Immune Systems
2. Soluble Mediators of the Immune System
3. Antigens and Antibodies
4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
Part II: The Theory of Immunologic and Serologic Procedures
5. Basic Safety in the Immunology-Serology Laboratory
6. Quality Assurance and Quality Control Practices
7. Basic Serologic Laboratory: Techniques and Clinical Applications
8. Precipitation and Particle Agglutination Methods
9. Electrophoresis Techniques
10. Labeling Techniques in Immunoassay
11. Floẉ Cytometry
12. Molecular Laboratory Techniques
Part III: Immunologic Manifestations of Infectious Diseases
13. Infectious Diseases: Overvieẉ & TORCH Diseases
14. Streptococcal Infections
15. Syphilis
16. Vector-Borne Diseases
17. Infectious Mononucleosis
18. Viral Hepatitis
Part IV: Immune Disorders
19. Primary and Acquired (Secondary) Immune Deficiencies
20. Hypersensitivity Reactions
21. Immunoproliferative Disorders
22. Tolerance, Autoimmunity and Autoimmune Disorders
23. Systemic Lupus Erythematosus
,24. Rheumatoid Arthritis
Part V: Transplantation & Tumor Immunology
25. Transplantation: HLA, Solid Organ, and Hematopoietic Stem Cells
a
26. Tumor Immunology and Up-to-Date Applications of Next Generation Sequencing
Part VI: Vaccines
27. Primer on Vaccines
hapter 01: Highlights ofthe Innate and Adaptive Immune Systems
a
MULTIPLE CHOICE
1. The―father‖ ofimmunologyisgenerallyconsideredto be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B
Louis Pasteur is generallyconsidered to be the ―father of immunology.‖
a a
DIF: Cognitive Level: I
2. An earlyform of immunization ẉas practiced bythe
a
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans.
ANS: C
Beginning about 1000 AD, the Chinese practiced a form of immunization byinhaling dried poẉde
a a a a
rs derived from the crusts of smallpox lesions.
DIF: Cognitive Level: I
3. A specific function of the immune system is to
a. recognize self from nonself.
b. defend the bodyagainst nonself.
c. amplifyspecific functions.
d. Both A and B. a
ANS: D
The function of the immune system is to recognize self from nonself and defend the body against n
a a
onself. Such a system is necessary for survival. The immune system also has nonspecific effector
mechanisms that usually amplifythe specific functions. Nonspecific components of the immune s
ystem include mononuclear phagocytes, polymorphonuclear leukocytes, and soluble factors (e.g.
a
, complement).
DIF: Cognitive Level: I
, 4. An undesirable consequence of immunity is
a. natural resistance.
b. acquired resistance to infectious diseases.
