ABRAMS’ CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE,
12TH EDITION (FRANDSEN, 2021), ALL CHAPTERS 1 – 61 COVERED
GRADED A+ 100% VERIFIED.
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, Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive disorder has been
prescribed oralparoxetine hydrochloride. What is the expected effect
for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS >> B
Rationale: Drugs that produce systemic effects are taken into the body,
circulated through the bloodstream to their sites of action in various body
tissues, and eventually eliminated from the body. Curative agents are given to
cure a disease process. In this case, paroxetine hydrochloride will control the
symptoms but not cure the disorder. Drugs with local effects,such as sunscreen
and local anesthetics, act mainly at the site of application. Paroxetine
hydrochloride is not administered parenterally. Parenteral agents are
administered subcutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
TherapiesTOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been cheGmRicAalDlyEm
SoBdOifOied.
S TWhaOt M
.C is another name for this
type of medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS >> B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring
substances that have been chemically modified. Synthetic drugs are more
standardized in their chemicalcharacteristics, more consistent in their effects,
and less likely to produce allergic reactions. Biotechnology drugs involve
manipulating DNA and RNA and recombining genes into hybrid molecules that
can be inserted into living organisms. Prototype drugs are the first drug of a
particular group to be developed.