Created By: A Solution
TEST BANK FOR Evolutionary Analysis 5th Edition
by Herron Jon; Freeman Scott ISBN 9780321998378
Chapter 1-20 A+
Chapter 1 A Case for Evolutionary Thinking: Understanding HIV
1) In which of the following regions has AIDS killed the largest number of individuals?
A) India
B) Sub-Saharan Africa
C) United States
D) China
E) United Kingdom Answer: B Section: 1.1
Skill: Knowledge/Comprehension
2) The HIV virus contains all of the following components except .
A) integrase
B) double-stranded RNA
C) single-stranded RNA
D) reverse transcriptase
E) protease Answer: B Section: 1.1
Skill: Knowledge/Comprehension
3) The acronym HIV stands for which of the following?
A) human intercellular virus
B) human immune virus
C) human immunodeficiency virus
D) human immunity virus
E) human immunodeficiency vector Answer: C
Section: 1.1
Skill: Knowledge/Comprehension
4) Which of the following enzymes is responsible for transcribing viral RNA into DNA?
A+ Page 1
,Created By: A Solution
A) RNA polymerase
B) reverse transcriptase
C) DNA polymerase
D) reverse integrase
E) RNA duplicase Answer: B Section: 1.1
Skill: Knowledge/Comprehension
5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5. On
what type of cells are these proteins typically observed?
A) plasma cells
B) dendritic cells
C) effector helper T cells
D) memory helper T cells
E) both C and D Answer: E Section: 1.1
Skill: Knowledge/Comprehension
6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the
blood drops below what concentration?
A) 2,000 cells per cubic millimeter
B) 1,000 cells per cubic millimeter
C) 500 cells per cubic millimeter
D) 200 cells per cubic millimeter
E) No CD4 T cells are observed. Answer: D
Section: 1.1
Skill: Knowledge/Comprehension
7) Which of the following drug categories are used to treat HIV infections?
A) integrase inhibitors
B) protease inhibitors
C) reverse transcriptase inhibitors
D) DNAse inhibitors
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,Created By: A Solution
E) fusion inhibitors Answer: D Section: 1.2
Skill: Knowledge/Comprehension
8) Coreceptor inhibitors block HIV infection by preventing which of the following?
A) binding of the HIV virion onto the plasma membrane
B) binding of the HIV virion onto the CCR5 receptor
C) binding of the HIV virion onto the gp120 protein
D) degrading the coreceptor so the virion cannot attach
E) binding of the HIV virion onto the CD4 receptor Answer: B
Section: 1.2
Skill: Application/Analysis
9) What is the effect of the ∆32 allele of CCR5 on HIV binding?
A) appears on the surface of CD4 T cells, but the HIV virion is unable to infect the host cell
B) does not appear on the surface of CD4 T cells
C) appears on the surface of the CD4 T cells and inactivates the virion upon binding
D) interferes with binding of the virion to the CD4 receptor protein
E) appears on the surface of the CD4 T cells and causes the virion to lyse upon binding
Answer: B
Section: 1.3
Skill: Application/Analysis
10) The ∆32 allele of CCR5 is found at the highest frequency in which of the following
populations?
A) Africans
B) Japanese
C) North Americans
D) Europeans
E) South Americans Answer: D Section: 1.3
Skill: Knowledge/Comprehension
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11) HIV-1 is believed to have been transmitted to humans from which of the following
organisms?
A) gorillas
B) sooty mangabeys
C) African green monkeys
D) chimpanzees
E) baboons Answer: D Section: 1.4
Skill: Knowledge/Comprehension
12) HIV-1 Group M is responsible for 95% of human infections. When is it estimated that
HIV-1 Group M was transferred to humans?
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer: C Section: 1.4
Skill: Knowledge/Comprehension
13) Antibodies and killer T cells recognize HIV or HIV-infected cells by binding to short
pieces of viral proteins displayed on the virus or the infected host cell. These short pieces of viral
proteins are called .
A) coat proteins
B) virosomes
C) proteosomes
D) epitopes
E) episomes Answer: D
Section: 1.5
Skill: Knowledge/Comprehension
14) Tetherin is an important protein produced by the host. What is the function of tetherin in
protecting a host cell from HIV?
A+ Page 4
TEST BANK FOR Evolutionary Analysis 5th Edition
by Herron Jon; Freeman Scott ISBN 9780321998378
Chapter 1-20 A+
Chapter 1 A Case for Evolutionary Thinking: Understanding HIV
1) In which of the following regions has AIDS killed the largest number of individuals?
A) India
B) Sub-Saharan Africa
C) United States
D) China
E) United Kingdom Answer: B Section: 1.1
Skill: Knowledge/Comprehension
2) The HIV virus contains all of the following components except .
A) integrase
B) double-stranded RNA
C) single-stranded RNA
D) reverse transcriptase
E) protease Answer: B Section: 1.1
Skill: Knowledge/Comprehension
3) The acronym HIV stands for which of the following?
A) human intercellular virus
B) human immune virus
C) human immunodeficiency virus
D) human immunity virus
E) human immunodeficiency vector Answer: C
Section: 1.1
Skill: Knowledge/Comprehension
4) Which of the following enzymes is responsible for transcribing viral RNA into DNA?
A+ Page 1
,Created By: A Solution
A) RNA polymerase
B) reverse transcriptase
C) DNA polymerase
D) reverse integrase
E) RNA duplicase Answer: B Section: 1.1
Skill: Knowledge/Comprehension
5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5. On
what type of cells are these proteins typically observed?
A) plasma cells
B) dendritic cells
C) effector helper T cells
D) memory helper T cells
E) both C and D Answer: E Section: 1.1
Skill: Knowledge/Comprehension
6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the
blood drops below what concentration?
A) 2,000 cells per cubic millimeter
B) 1,000 cells per cubic millimeter
C) 500 cells per cubic millimeter
D) 200 cells per cubic millimeter
E) No CD4 T cells are observed. Answer: D
Section: 1.1
Skill: Knowledge/Comprehension
7) Which of the following drug categories are used to treat HIV infections?
A) integrase inhibitors
B) protease inhibitors
C) reverse transcriptase inhibitors
D) DNAse inhibitors
A+ Page 2
,Created By: A Solution
E) fusion inhibitors Answer: D Section: 1.2
Skill: Knowledge/Comprehension
8) Coreceptor inhibitors block HIV infection by preventing which of the following?
A) binding of the HIV virion onto the plasma membrane
B) binding of the HIV virion onto the CCR5 receptor
C) binding of the HIV virion onto the gp120 protein
D) degrading the coreceptor so the virion cannot attach
E) binding of the HIV virion onto the CD4 receptor Answer: B
Section: 1.2
Skill: Application/Analysis
9) What is the effect of the ∆32 allele of CCR5 on HIV binding?
A) appears on the surface of CD4 T cells, but the HIV virion is unable to infect the host cell
B) does not appear on the surface of CD4 T cells
C) appears on the surface of the CD4 T cells and inactivates the virion upon binding
D) interferes with binding of the virion to the CD4 receptor protein
E) appears on the surface of the CD4 T cells and causes the virion to lyse upon binding
Answer: B
Section: 1.3
Skill: Application/Analysis
10) The ∆32 allele of CCR5 is found at the highest frequency in which of the following
populations?
A) Africans
B) Japanese
C) North Americans
D) Europeans
E) South Americans Answer: D Section: 1.3
Skill: Knowledge/Comprehension
A+ Page 3
, Created By: A Solution
11) HIV-1 is believed to have been transmitted to humans from which of the following
organisms?
A) gorillas
B) sooty mangabeys
C) African green monkeys
D) chimpanzees
E) baboons Answer: D Section: 1.4
Skill: Knowledge/Comprehension
12) HIV-1 Group M is responsible for 95% of human infections. When is it estimated that
HIV-1 Group M was transferred to humans?
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer: C Section: 1.4
Skill: Knowledge/Comprehension
13) Antibodies and killer T cells recognize HIV or HIV-infected cells by binding to short
pieces of viral proteins displayed on the virus or the infected host cell. These short pieces of viral
proteins are called .
A) coat proteins
B) virosomes
C) proteosomes
D) epitopes
E) episomes Answer: D
Section: 1.5
Skill: Knowledge/Comprehension
14) Tetherin is an important protein produced by the host. What is the function of tetherin in
protecting a host cell from HIV?
A+ Page 4
