Page | 1
Psychopharmacology 552 Exam 3 Questions
with Detailed Verified Answers
Naloxone (Narcan) Ans: opiate antagonist, reverses opioid induced respiratory
depression
Treatment of choice for all patients with opioid use disorder
Very short half-life
What is Methadone also known as? Ans: Dolophine
What type of opioid receptor agonist is Methadone? Ans: Long-acting full agonist at
the mu receptor
How often is Methadone dosed? Ans: Once daily
In what type of programs is Methadone use restricted? Ans: Federally licensed
substance abuse treatment programs
What should be monitored when using Methadone? Ans: QTC prolongation
What is Buprenorphine (Buprenex, Sublocade)? Ans: Partial Opioid receptor agonist
, Page | 2
What is the function of Buprenorphine/Naloxone (Suboxone)? Ans: Opioid
antagonist
What effect does Buprenorphine have on cravings? Ans: Decreases cravings
What precaution is needed when using Suboxone in outpatient settings? Ans:
Waiver needed to prescribe in outpatient settings
What can happen if Buprenorphine is used too soon after a full opioid agonist? Ans:
Can precipitate withdrawal
How does Suboxone interact with residual opioids from mu receptors? Ans: It will
displace any residual opioids from the mu receptors
What is the route of administration for Suboxone? Ans: Sublingual preparation
In what situation can Suboxone be used in managing pain? Ans: Opioid Use disorder
w/ comorbid pain
What type of antagonist is Naltrexone? Ans: Competitive opioid antagonist
What can happen if Naltrexone is used within 7 days of heroin use? Ans: Precipitate
withdrawal
How is Naltrexone available for use? Ans: Orally or monthly depot injection
When is Naltrexone considered the treatment of choice? Ans: For highly motivated
patients
, Page | 3
What is a potential risk associated with Naltrexone use? Ans: Risk for LFT elevation
Naltrexone Ans: Available PO (Revia) Available IM (Vivitrol)
Buprenorphine (Buprenex, Sublocade) Buprenorphine/Naloxone (Suboxone) Ans:
Suboxone= available Buccal film, sublingual film, sublingual tab Buprenorphine=
Available sublingual tab; subdermal implant, SQ injection
What are the common symptoms of opioid overdose? Ans: Miosis, Hypotension,
Bradycardia, Low RR, Unconsciousness
How is opioid overdose managed? Ans: Naloxone
What are the symptoms of opioid withdrawal? Ans: Anxiety, Lacrimation, Muscle
aches, Abdominal cramps, Diarrhea, Seizures
What medications are used for opioid withdrawal management? Ans:
Buprenorphine/naloxone, Clonidine, Bentyl
In opioid detoxification, which medication is more effective at suppressing withdrawal
symptoms towards the end of the taper? Ans: Buprenorphine (compared to
methadone)
What are some symptoms of cocaine use? Ans: Auditory hallucinations, agitation,
violent behavior, muscle twitching, hypertension, tachycardia
How is lorazepam used in the treatment of cocaine use disorder? Ans: It is used to
treat agitation and muscle twitching associated with cocaine use
Psychopharmacology 552 Exam 3 Questions
with Detailed Verified Answers
Naloxone (Narcan) Ans: opiate antagonist, reverses opioid induced respiratory
depression
Treatment of choice for all patients with opioid use disorder
Very short half-life
What is Methadone also known as? Ans: Dolophine
What type of opioid receptor agonist is Methadone? Ans: Long-acting full agonist at
the mu receptor
How often is Methadone dosed? Ans: Once daily
In what type of programs is Methadone use restricted? Ans: Federally licensed
substance abuse treatment programs
What should be monitored when using Methadone? Ans: QTC prolongation
What is Buprenorphine (Buprenex, Sublocade)? Ans: Partial Opioid receptor agonist
, Page | 2
What is the function of Buprenorphine/Naloxone (Suboxone)? Ans: Opioid
antagonist
What effect does Buprenorphine have on cravings? Ans: Decreases cravings
What precaution is needed when using Suboxone in outpatient settings? Ans:
Waiver needed to prescribe in outpatient settings
What can happen if Buprenorphine is used too soon after a full opioid agonist? Ans:
Can precipitate withdrawal
How does Suboxone interact with residual opioids from mu receptors? Ans: It will
displace any residual opioids from the mu receptors
What is the route of administration for Suboxone? Ans: Sublingual preparation
In what situation can Suboxone be used in managing pain? Ans: Opioid Use disorder
w/ comorbid pain
What type of antagonist is Naltrexone? Ans: Competitive opioid antagonist
What can happen if Naltrexone is used within 7 days of heroin use? Ans: Precipitate
withdrawal
How is Naltrexone available for use? Ans: Orally or monthly depot injection
When is Naltrexone considered the treatment of choice? Ans: For highly motivated
patients
, Page | 3
What is a potential risk associated with Naltrexone use? Ans: Risk for LFT elevation
Naltrexone Ans: Available PO (Revia) Available IM (Vivitrol)
Buprenorphine (Buprenex, Sublocade) Buprenorphine/Naloxone (Suboxone) Ans:
Suboxone= available Buccal film, sublingual film, sublingual tab Buprenorphine=
Available sublingual tab; subdermal implant, SQ injection
What are the common symptoms of opioid overdose? Ans: Miosis, Hypotension,
Bradycardia, Low RR, Unconsciousness
How is opioid overdose managed? Ans: Naloxone
What are the symptoms of opioid withdrawal? Ans: Anxiety, Lacrimation, Muscle
aches, Abdominal cramps, Diarrhea, Seizures
What medications are used for opioid withdrawal management? Ans:
Buprenorphine/naloxone, Clonidine, Bentyl
In opioid detoxification, which medication is more effective at suppressing withdrawal
symptoms towards the end of the taper? Ans: Buprenorphine (compared to
methadone)
What are some symptoms of cocaine use? Ans: Auditory hallucinations, agitation,
violent behavior, muscle twitching, hypertension, tachycardia
How is lorazepam used in the treatment of cocaine use disorder? Ans: It is used to
treat agitation and muscle twitching associated with cocaine use
