NUR2474 Pharmacology Module 8 Quiz Review
Questions and Answers with 100% Complete Solutions
UPDATED!!!
Tips: There will be a number of negatively worded questions.
Please be mindful of that.
Topics review:
1. Physical dependence vs addiction with opiate use
a. Tolerance
i. Increased doses needed to obtain the same
response
ii. Develops with analgesia, euphoria, sedation,
and respiratory depression
iii. Cross-tolerance to other opioid agonists iv. No
tolerance to miosis or constipation develops
b. Physical dependence
i. Abstinence syndrome with abrupt
discontinuation
ii. About 10 hours after last dose, the initial
reaction occurs and includes yawning,
rhinorrhea, and sweating
iii. Progresses to violent sneezing, weakness,
nausea, vomiting, diarrhea, abdominal cramps,
, lOMoAR cPSD| 47061011
bone and muscle pain, muscle spasms, and
kicking movements
iv. Lasts 7 to 10 days if untreated
v. Withdrawal is unpleasant but not lethal, as it
may be with CNS depressants
vi. Patients dependence does not mean addiction
vii. Short-term use does not lead to dependence
viii. If used as prescribed, it does not lead to
dependence.
1.Wean patient of medication slowly, and they
will be fine.
c. It is not common for patients to abuse opioids
2. PCA pump patient family education
a. Educate family members not to operate the PCA
pump, even if patient seems to be in pain.
b. ONLY PATIENT USES PUMP!
3. Antidote for opiates
a.Naloxone
i.Reversal of opioid overdose
1. Drug of choice with pure opioid agonist
overdose
2. Titrated cautiously with physical
dependence ii. Reversal of postoperative
opioid effects