Test Bank For Psychopharmacology Drugs the Brain and Behavior 3th Edition By Meyer Nursing Complete Guide|A+

, Chapter 1: Principles of Pharmacology
nn nn nn nn




Multiple nnChoice

1. refer(s) nnto nnspecific nnmolecular nnchanges nnthat nnoccur nnwhen nna nndrug
nnbinds nnto nna nnparticular nntarget nnsite nnor nnreceptor, nnwhile are nnthe nnresulting
nnwidespread nnalterations nnin nnfunction.

a. Drug nnaction; nntherapeutic nneffects
b. Side nneffects; nndrug nneffects
c. Therapeutic nneffects; nnside nneffects
d. Drug nnaction; nndrug nneffects
Answer: nnd
Textbook nnReference: nnPharmacology: nnThe nnScience nnof nnDrug nnAction

2. After nndrug nnadministration nnhas nnoccurred, nnthe nnamount nnof nndrug nnin nnthe nnblood nnthat
nnis nnfree nnto nnbind nnat nnspecific nntarget nnsites nnis nnreferred nnto nnas

a. the nntherapeutic nndose.
b. first-pass nneffects.
c. bioavailability.
d. ED50.
Answer: nnc
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

3. The nnspecific nnmolecular nnchanges nnthat nnoccur nnwhen nna nndrug nnbinds nnto nna nnparticular
nntarget nnsite nnor nnreceptor nnare nnreferred nnto nnas

a. drug nneffects.
b. drug nnaction.
c. side nneffects.
d. placebo nneffects.
Answer: nnb
Textbook nnReference: nnPharmacology: nnThe nnScience nnof nnDrug nnAction

4. Which nnof nnthe nnfollowing nnis nnnot nna nnpossible nnexplanation nnfor nnplacebo nn effects?
a. Pavlovian nnconditioning
b. Genetic nnvariation
c. Drug nncompetition
d. Expectation nnof nnoutcome
Answer: nnc
Textbook nnReference: nnPharmacology: nnThe nnScience nnof nnDrug nnAction




Page nn 1 nn of
nn1

,5. The administration nnof nnoxytocin nnhas nnbeen nnproposed nnas nna nntreatment nn for
nnautism.

a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: nnc
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

6. Which nnfactor nndoes nnnot nnaffect nnthe nnpharmacokinetics nnof nna nndrug?
a. Route nnof nnadministration
b. Lipid nnsolubility
c. Depot nnbinding
d. Drug nnaction
Answer: nnd
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

7. First-pass nnmetabolism nnoccurs nnwhen nndrugs nnare nntaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: nna
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

8. The nnarea nnpostrema nn is nnone nnarea nn in nnthe nnbrain nnwhere nnthe is nnnot nncomplete.
a. cerebrospinal nnfluid
b. blood–brain nnbarrier
c. choroid nnplexus
d. phospholipid nnmembrane
Answer: nnb
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

9. First-pass nnmetabolism nnoccurs nnwith nnorally nnadministered nndrugs nnbecause
a. their nnabsorption nnis nnslowed nnby nnfood.
b. drugs nnabsorbed nninto nnthe nnbloodstream nnfrom nnthe nnstomach nngo nnto nnthe nnliver nnon
nnthe nnway nnto nngeneral nncirculation.

c. drugs nnmust nnfirst nn survive nnthe nnacidic nnenvironment nn of nnthe nnstomach.
d. salivary nnenzymes nn in nnthe nnmouth nnbegin nnthe nnprocess nnof nnmetabolism.
Answer: nnb
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

10. Toxic nnsubstances nnin nnthe nnblood nntrigger nna nnvomiting nnresponse nnby nnactivating nnthe
a. blood–brain nnbarrier.
b. choroid nnplexus.
c. area nnpostrema.
d. median nneminence.



Page nn 2 nn of
nn2

, Answer: nnc
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

11. Drugs nnadministered nn_ have nnthe nnmost nnrapid nnonset nnof nnaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: nnd
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

12. Ionization nnof nna nndrug nndepends nnon nnthe of nnthe nnsolution nnand nnthe of
nnthe nndrug.

a. pH; nnpKa
b. pKa; nnpH
c. concentration; nnlipid nnsolubility
d. pH; nnconcentration
Answer: nna
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

13. The nnabsorption nnof nna nndrug nndepends nnon nnall nnof nnthe nn following nnexcept
a. lipid nnsolubility.
b. ionization.
c. body nntemperature.
d. the nnconcentration nnof nnthe nndrug.
Answer: nnc
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

14. Drugs nnthat nn are should nnbe nnavoided nnby nnwomen nnof nnchildbearing nnage.
a. teratogenic
b. able nnto nncross nnthe nnplacental nnbarrier
c. psychoactive
d. highly nnlipid-soluble
Answer: nna
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

15. Agents nnthat nninduce nndevelopmental nnabnormalities nn in nna nnfetus nnare nnknown nnas
a. psychoactive nndrugs.
b. illicit nndrugs.
c. teratogens.
d. placental nndrugs.
Answer: nnc
Textbook nnReference: nnPharmacokinetic nnFactors nnDetermining nnDrug nnAction

16. Depot nnbinding nnis nnsaid nnto nnoccur nnwhen nndrugs
a. bind nnto nntheir nntarget nn sites.




Page nn 3 nn of
nn3