Evolve HESI Pharmacology Exam 2024
(Latest 2025 Update) – Correct, Detailed
& Verified Answers | 100% Accurate | A
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Drug Classifications (15 Questions)
1. A nurse is administering digoxin 0.25 mg daily. What should the nurse monitor?
A) Blood pressure
B) Apical pulse
C) Temperature
D) Respiratory rate
Answer: B
Rationale: Digoxin slows heart rate, requiring monitoring of the apical pulse for
bradycardia per 2025 HESI guidelines.
2. Which medication is classified as a beta-blocker for hypertension?
A) Lisinopril
B) Atenolol
C) Losartan
D) Amlodipine
Answer: B
Rationale: Atenolol is a beta-blocker that reduces heart rate and blood pressure, unlike
ACE inhibitors (lisinopril), ARBs (losartan), or calcium channel blockers (amlodipine).
3. What is the primary action of metformin in type 2 diabetes management?
A) Stimulates insulin release
B) Decreases hepatic glucose production
C) Increases glucagon secretion
D) Enhances glucose reabsorption
Answer: B
Rationale: Metformin reduces blood glucose by decreasing liver glucose production and
increasing insulin sensitivity.
4. Which medication is a proton pump inhibitor for GERD?
A) Famotidine
B) Omeprazole
C) Ranitidine
D) Sucralfate
Answer: B
Rationale: Omeprazole inhibits the proton pump to reduce gastric acid production, unlike
H2 blockers (famotidine, ranitidine) or mucosal protectants (sucralfate).
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5. NGN: Select-All-That-Apply - Which medications are classified as loop diuretics?
(Select all that apply.)
A) Furosemide
B) Hydrochlorothiazide
C) Bumetanide
D) Spironolactone
Answer: A, C
Rationale: Furosemide and bumetanide are loop diuretics; hydrochlorothiazide is a
thiazide diuretic, and spironolactone is a potassium-sparing diuretic.
6. A patient is prescribed levothyroxine for hypothyroidism. What is its primary
action?
A) Inhibits thyroid hormone production
B) Replaces thyroid hormone
C) Stimulates TSH release
D) Blocks iodine uptake
Answer: B
Rationale: Levothyroxine replaces deficient thyroid hormone in hypothyroidism.
7. Which medication is a short-acting beta agonist for asthma?
A) Albuterol
B) Fluticasone
C) Montelukast
D) Ipratropium
Answer: A
Rationale: Albuterol is a short-acting beta agonist used for acute asthma relief.
8. What is the therapeutic use of warfarin?
A) Pain relief
B) Anticoagulation
C) Blood pressure control
D) Seizure prevention
Answer: B
Rationale: Warfarin prevents thrombus formation by inhibiting vitamin K-dependent
clotting factors.
9. Which medication is a first-line treatment for status epilepticus?
A) Phenytoin
B) Lorazepam
C) Carbamazepine
D) Valproic acid
Answer: B
Rationale: Lorazepam, a benzodiazepine, is first-line for status epilepticus due to its
rapid onset.
10. A patient is prescribed clopidogrel. What is its primary action?
A) Inhibits clotting factors
B) Inhibits platelet aggregation
C) Enhances fibrinolysis
D) Blocks thrombin
Answer: B