6/26/25, 5:43 PM PMHNP Board
PMHNP Board\NEWEST VERSION
\COMPLETE QUESTIONS AND ACCURATE DETAILED
ANSWERS \VERIFIED SOLUTIONS ALREADY GRADED
A+|LATEST UPDATE 2025
CYP1A2, When an individual is tx with clozapine and
Which cytochrome (CYP)
decreases tobacco (smoking only not patches or gum)
enzyme is implicated as a
use, the clozapine level will increase, as the tobacco is
tobacco inducer when an
an inducer to the clozapine, and the patent no
individual is treated on
longer needs the higher dose of clozapine.
clozapine?
The risk of bleeding on SSRI, Pharmacodynamics
NSAIDS, or aspirin, is an
example of?
Pharmacokinetics (PK) what the body does to the drug
What is Pharmacokinetics
(absorption, distribution, metabolism, and excretion.
verses
Pharmacodynamics (PD) is how the drug affects the
Pharmacodynamics?
body.
What are benztropine Anticholinergic mediation used for extrapyramidal side effects
(Cogentin) and (EPS).
trihexyphenidyl (Artane)?
What direct-acting bromocriptine (Parlodel) is recommended as a direct
dopamine receptor agonist acting dopamine receptor agonist to help decrease
is recommended to be used the dopamine blockade. And Dantrolene , a muscle
in the tx of neuroleptic relaxant.
malignant syndrome
(NMS) to help lower the
dopamine receptor
blockade?
What is dantrolene (Dantrium) A muscle relaxant
?
A mood stabilizer most lamotrigine (Lamictal)
associated with Stevens-
Johnson syndrome (a
https://quizlet.com/1053069249/pmhnp-board-flash-cards/?funnelUUID=6ae0a719-8288-4016-bb2f-bd131e7f6bcc 1/52
,6/26/25, 5:43 PM PMHNP Board
potentially life-threatening
rash red or purple rash that
spreads and forms blisters
leading to skin eventually
dies and peels off)?
Gamma-Aminobutyric Acid GABA is a inhibitory neurotransmitter. GABA decreases
(GABA) works by? brain activity. Increasing GABA decreases anxiety and
can induce a drowsy or calming effect.
https://quizlet.com/1053069249/pmhnp-board-flash-cards/?funnelUUID=6ae0a719-8288-4016-bb2f-bd131e7f6bcc 2/52
,6/26/25, 5:43 PM PMHNP Board
Increasing levels of Increasing anxiety, by activating the
Corticotropin-releasing Adrenocorticotropic hormone (ACTH) from the pituitary
factor (CRF) in the gland. CRF effects our response to stress, addiction,
amygdala, hippocampus and and depression.
locus ceruleus affects the
body by?
What part of the brain is Prefrontal Cortex
implicated in modulate pain
due to loss of gray matter?
What therapy can decrease Transcranial magnetic stimulation.
pain in the prefrontal
cortex?
Which serotonin receptor The mechanism of action that makes an antipsychotic
antagonism makes an medication "atypical" is related to the 5HT2A receptor
antipsychotic "atypical"? antagonism and D2 receptor antagonism.
5HT4A, 5HT3A, 5HT2A, 5HT1A
What is a first sign of unilateral ringing in ear
acoustic neuroma when a
patient complains of
tinnitus?
DC Abilify start Benztropine Mesylates 1 mg po BID for 5
days and return to provider for bipolar management.
22 y.o. male Bipolar c/0 of Aripiprazole (Abilify) is a third generation atypical
Oculogyric Crisis (acute antipsychotic and a dopamine serotonin system
dystonia) on 15 mg of Abilify stabilizer (DSS) that is effective against positive and
Q4 days ago what do you and negative symptoms of schizophrenia. It has a low
do? propensity for extrapyramidal side effects, causes
minimal weight gain, sedation, produces no elevation
in serum prolactin levels and no cause of
prolongation of QTc intervals.
A gray opaque band seen around the cornea separated
Arcus Senilis is? When
from the limbus by a narrow clear zone. When seen in
seen in clients before the
clients before the age of 40 is is associated with
age of 40 is associated with
Hyperlipidemia.
?
https://quizlet.com/1053069249/pmhnp-board-flash-cards/?funnelUUID=6ae0a719-8288-4016-bb2f-bd131e7f6bcc 3/52
, 6/26/25, 5:43 PM PMHNP Board
Antidepressants Citalopram (Celexa) and a Atypical second generation
associated with dose- antipsychotic Ziprasidone (Geodon) prolongs QT
related cardiovascular interval)
adverse effects ? An a
typical second generation
antipsychotic associated
with OT prolonged
intervals?
Extrapyramidal Side Effects
abruptly stopping can cause cholinergic rebound,
Anticholinergic withdrawal
syndrome symptoms of which include nausea, sweating, and
urinary urgency.
Neuroleptic Malignant acute mental status changes, fever, rigidity.
Syndrome
antidepressants, Prescribing and SSRI with a MAOI
(increase serotonin, norepinephrine, and dopamine),
Serotonin Syndrome is caused
by? placing patient on more than one SSRI, SSRI and St.
Johns Wart will increase Serotonin. Imitrex, some
retroviral drugs, Benzos, progesterone.
Negative symptoms are related to DA deficit in the
Dopamine pathways of
cerebral cortex. Positive symptoms are related to DA
negative and positive
excess in the nucleus accumbent and mesolimbic
symptoms of schizophrenia?
systems.
Hematologic changes Leukocytosis (WBC increase therefore order CBC during therapy
associated with lithium? to monitor tx)
Serious side effect of Priapism
trazodone (Desyrel)?
An inverse agonist has the True, an inverse agonist does the opposite of an agonist
opposite affect of an by causing the receptor to close the ion channel.
agonist?
60 y.o. female with Bipolar a manic episode, Corticosteroids have been known to
I disorder on valproate be a pharmacologic cause of mania.
and risperidone is
prescribed
corticosteroids you
concern is?
https://quizlet.com/1053069249/pmhnp-board-flash-cards/?funnelUUID=6ae0a719-8288-4016-bb2f-bd131e7f6bcc 4/52
PMHNP Board\NEWEST VERSION
\COMPLETE QUESTIONS AND ACCURATE DETAILED
ANSWERS \VERIFIED SOLUTIONS ALREADY GRADED
A+|LATEST UPDATE 2025
CYP1A2, When an individual is tx with clozapine and
Which cytochrome (CYP)
decreases tobacco (smoking only not patches or gum)
enzyme is implicated as a
use, the clozapine level will increase, as the tobacco is
tobacco inducer when an
an inducer to the clozapine, and the patent no
individual is treated on
longer needs the higher dose of clozapine.
clozapine?
The risk of bleeding on SSRI, Pharmacodynamics
NSAIDS, or aspirin, is an
example of?
Pharmacokinetics (PK) what the body does to the drug
What is Pharmacokinetics
(absorption, distribution, metabolism, and excretion.
verses
Pharmacodynamics (PD) is how the drug affects the
Pharmacodynamics?
body.
What are benztropine Anticholinergic mediation used for extrapyramidal side effects
(Cogentin) and (EPS).
trihexyphenidyl (Artane)?
What direct-acting bromocriptine (Parlodel) is recommended as a direct
dopamine receptor agonist acting dopamine receptor agonist to help decrease
is recommended to be used the dopamine blockade. And Dantrolene , a muscle
in the tx of neuroleptic relaxant.
malignant syndrome
(NMS) to help lower the
dopamine receptor
blockade?
What is dantrolene (Dantrium) A muscle relaxant
?
A mood stabilizer most lamotrigine (Lamictal)
associated with Stevens-
Johnson syndrome (a
https://quizlet.com/1053069249/pmhnp-board-flash-cards/?funnelUUID=6ae0a719-8288-4016-bb2f-bd131e7f6bcc 1/52
,6/26/25, 5:43 PM PMHNP Board
potentially life-threatening
rash red or purple rash that
spreads and forms blisters
leading to skin eventually
dies and peels off)?
Gamma-Aminobutyric Acid GABA is a inhibitory neurotransmitter. GABA decreases
(GABA) works by? brain activity. Increasing GABA decreases anxiety and
can induce a drowsy or calming effect.
https://quizlet.com/1053069249/pmhnp-board-flash-cards/?funnelUUID=6ae0a719-8288-4016-bb2f-bd131e7f6bcc 2/52
,6/26/25, 5:43 PM PMHNP Board
Increasing levels of Increasing anxiety, by activating the
Corticotropin-releasing Adrenocorticotropic hormone (ACTH) from the pituitary
factor (CRF) in the gland. CRF effects our response to stress, addiction,
amygdala, hippocampus and and depression.
locus ceruleus affects the
body by?
What part of the brain is Prefrontal Cortex
implicated in modulate pain
due to loss of gray matter?
What therapy can decrease Transcranial magnetic stimulation.
pain in the prefrontal
cortex?
Which serotonin receptor The mechanism of action that makes an antipsychotic
antagonism makes an medication "atypical" is related to the 5HT2A receptor
antipsychotic "atypical"? antagonism and D2 receptor antagonism.
5HT4A, 5HT3A, 5HT2A, 5HT1A
What is a first sign of unilateral ringing in ear
acoustic neuroma when a
patient complains of
tinnitus?
DC Abilify start Benztropine Mesylates 1 mg po BID for 5
days and return to provider for bipolar management.
22 y.o. male Bipolar c/0 of Aripiprazole (Abilify) is a third generation atypical
Oculogyric Crisis (acute antipsychotic and a dopamine serotonin system
dystonia) on 15 mg of Abilify stabilizer (DSS) that is effective against positive and
Q4 days ago what do you and negative symptoms of schizophrenia. It has a low
do? propensity for extrapyramidal side effects, causes
minimal weight gain, sedation, produces no elevation
in serum prolactin levels and no cause of
prolongation of QTc intervals.
A gray opaque band seen around the cornea separated
Arcus Senilis is? When
from the limbus by a narrow clear zone. When seen in
seen in clients before the
clients before the age of 40 is is associated with
age of 40 is associated with
Hyperlipidemia.
?
https://quizlet.com/1053069249/pmhnp-board-flash-cards/?funnelUUID=6ae0a719-8288-4016-bb2f-bd131e7f6bcc 3/52
, 6/26/25, 5:43 PM PMHNP Board
Antidepressants Citalopram (Celexa) and a Atypical second generation
associated with dose- antipsychotic Ziprasidone (Geodon) prolongs QT
related cardiovascular interval)
adverse effects ? An a
typical second generation
antipsychotic associated
with OT prolonged
intervals?
Extrapyramidal Side Effects
abruptly stopping can cause cholinergic rebound,
Anticholinergic withdrawal
syndrome symptoms of which include nausea, sweating, and
urinary urgency.
Neuroleptic Malignant acute mental status changes, fever, rigidity.
Syndrome
antidepressants, Prescribing and SSRI with a MAOI
(increase serotonin, norepinephrine, and dopamine),
Serotonin Syndrome is caused
by? placing patient on more than one SSRI, SSRI and St.
Johns Wart will increase Serotonin. Imitrex, some
retroviral drugs, Benzos, progesterone.
Negative symptoms are related to DA deficit in the
Dopamine pathways of
cerebral cortex. Positive symptoms are related to DA
negative and positive
excess in the nucleus accumbent and mesolimbic
symptoms of schizophrenia?
systems.
Hematologic changes Leukocytosis (WBC increase therefore order CBC during therapy
associated with lithium? to monitor tx)
Serious side effect of Priapism
trazodone (Desyrel)?
An inverse agonist has the True, an inverse agonist does the opposite of an agonist
opposite affect of an by causing the receptor to close the ion channel.
agonist?
60 y.o. female with Bipolar a manic episode, Corticosteroids have been known to
I disorder on valproate be a pharmacologic cause of mania.
and risperidone is
prescribed
corticosteroids you
concern is?
https://quizlet.com/1053069249/pmhnp-board-flash-cards/?funnelUUID=6ae0a719-8288-4016-bb2f-bd131e7f6bcc 4/52
