Immunology Exam 1 Practice Questions
with Verified Solutions
A young newly-married woman, JT, goes to her physician with concerns about a
"hereditary problem" described to her by her mother that was associated with her own
birth in 1968. Her family was poor and her mother received no medical prenatal care
before JT was born "blue" and covered with " splotches" and "bruises". Although an
earlier sibling had been born apparently normal , JT required multiple transfusions
before her condition stabilized, and two further pregnancies of her mother ended in
stillbirths. JT is concerned about the potential for development of similar problems in her
own pregnancies. Blood tests ordered by the physician confirm his suspicions. He
advises his patient: - ANSWER-She is RhD+, there is no risk to a fetus (Only a problem
if Mom is RhD-)
Allergies result from the production of ____________ directed against an antigen. -
ANSWER-IgE
Antibody proteins are also known as - ANSWER-Immunoglobulins
CD8 is associated with? - ANSWER-Cytotoxic T Cells
Each of the following statements concerning the variable regions of heavy chains and
the variable regions of light chains in a given antibody molecule is correct *EXCEPT*
A- They have the same amino acid sequence
B- They define the specificity for antigen
C- They are encoded on different chromosomes
D- They contain hypervariable regions - ANSWER-A- They have the same amino acid
sequence
Eosinophils do *NOT*
A- Stain with basic dyes
B- Contain a major basic protein
C- Contain peroxidase
D- Stain with the acid dye eosin red/pink - ANSWER-A - Stain with basic dyes
Basophil = Basic, Blue
Eosinophil = Acid, Red
IgE has a special propensity to become attached to what? - ANSWER-Basophils
, Immediately following a break in the skin, phagocytes engulf bacteria near the wound.
This is an example of an ___________________ immune response which is
__________________.
A- Adaptive, specific
B- Innate, specific
C- Innate, nonspecific
D- Adaptive, nonspecific - ANSWER-C- Innate, nonspecific
Immunological memory is a characteristic of both of these cells. - ANSWER-T and B
cells
Leukocytes expressing CD-4 receptors are - ANSWER-T-Helper Cells
Name the process a cell such as a neutrophil or a macrophage uses to ingest its prey? -
ANSWER-Phagocytosis
Neutrophils and macrophages can move together through the tissues via what? -
ANSWER-Ameboid Motion
Neutrophils and monocytes can squeeze through the pores of the blood capillaries by? -
ANSWER-Diapedesis
Polymorphonuclear (PMN) neutrophils attack bacteria by - ANSWER-Phagocytosis
Presence of D antigen in the blood means? - ANSWER-Rh+
Presence of no D antigen in the blood means? - ANSWER-Rh-
Reaction to poison ivy or poison oak is - ANSWER-A cell mediated response
Selective IgA deficiency is most commonly associated with which of the following?
A- Asthma
B- Recurrent sinopulmonary infections
C- Systemic lupus erythematosus
D- Myasthenia Gravis - ANSWER-B- Recurrent sinopulmonary infections
The cell that is considered to be one of the basic cells of the innate immune response is
what? - ANSWER-Macrophage
The cells that produce and secrete antibodies are - ANSWER-Plasma Cells
The class of immunoglobulin present in highest concentration in the blood of a human
newborn is? - ANSWER-IgG
with Verified Solutions
A young newly-married woman, JT, goes to her physician with concerns about a
"hereditary problem" described to her by her mother that was associated with her own
birth in 1968. Her family was poor and her mother received no medical prenatal care
before JT was born "blue" and covered with " splotches" and "bruises". Although an
earlier sibling had been born apparently normal , JT required multiple transfusions
before her condition stabilized, and two further pregnancies of her mother ended in
stillbirths. JT is concerned about the potential for development of similar problems in her
own pregnancies. Blood tests ordered by the physician confirm his suspicions. He
advises his patient: - ANSWER-She is RhD+, there is no risk to a fetus (Only a problem
if Mom is RhD-)
Allergies result from the production of ____________ directed against an antigen. -
ANSWER-IgE
Antibody proteins are also known as - ANSWER-Immunoglobulins
CD8 is associated with? - ANSWER-Cytotoxic T Cells
Each of the following statements concerning the variable regions of heavy chains and
the variable regions of light chains in a given antibody molecule is correct *EXCEPT*
A- They have the same amino acid sequence
B- They define the specificity for antigen
C- They are encoded on different chromosomes
D- They contain hypervariable regions - ANSWER-A- They have the same amino acid
sequence
Eosinophils do *NOT*
A- Stain with basic dyes
B- Contain a major basic protein
C- Contain peroxidase
D- Stain with the acid dye eosin red/pink - ANSWER-A - Stain with basic dyes
Basophil = Basic, Blue
Eosinophil = Acid, Red
IgE has a special propensity to become attached to what? - ANSWER-Basophils
, Immediately following a break in the skin, phagocytes engulf bacteria near the wound.
This is an example of an ___________________ immune response which is
__________________.
A- Adaptive, specific
B- Innate, specific
C- Innate, nonspecific
D- Adaptive, nonspecific - ANSWER-C- Innate, nonspecific
Immunological memory is a characteristic of both of these cells. - ANSWER-T and B
cells
Leukocytes expressing CD-4 receptors are - ANSWER-T-Helper Cells
Name the process a cell such as a neutrophil or a macrophage uses to ingest its prey? -
ANSWER-Phagocytosis
Neutrophils and macrophages can move together through the tissues via what? -
ANSWER-Ameboid Motion
Neutrophils and monocytes can squeeze through the pores of the blood capillaries by? -
ANSWER-Diapedesis
Polymorphonuclear (PMN) neutrophils attack bacteria by - ANSWER-Phagocytosis
Presence of D antigen in the blood means? - ANSWER-Rh+
Presence of no D antigen in the blood means? - ANSWER-Rh-
Reaction to poison ivy or poison oak is - ANSWER-A cell mediated response
Selective IgA deficiency is most commonly associated with which of the following?
A- Asthma
B- Recurrent sinopulmonary infections
C- Systemic lupus erythematosus
D- Myasthenia Gravis - ANSWER-B- Recurrent sinopulmonary infections
The cell that is considered to be one of the basic cells of the innate immune response is
what? - ANSWER-Macrophage
The cells that produce and secrete antibodies are - ANSWER-Plasma Cells
The class of immunoglobulin present in highest concentration in the blood of a human
newborn is? - ANSWER-IgG