m m m m m m m m
hapters 2024/2025 m
Table of Contents
m m
UNITmImThemCell
1 CellularmBiology
2 Altered mCellularmand mTissuemBiology:mEnvironmentalmAgents
3 ThemCellularmEnvironment:mFluidsmand mElectrolytes,mAcidsmand mBases
UNITmIImGenesmandmGene-EnvironmentmInteraction
4 Genesmand mGeneticmDiseases
5 Genes,mEnvironment-Lifestyle,mand mCommonmDiseases
6 Epigeneticsmand mDisease
UNITmIIImMechanismsmof mSelf-Defense
7 InnatemImmunity:mInflammationmand mWound mHealing
8 AdaptivemImmunity
9 AlterationsminmImmunity
10 Infection
11 Stressmand mDisease
UNITmIV mCellularmProliferation:mCancer
12 CancermBiology
13 CancermEpidemiology
14 CancerminmChildrenmand mAdolescents
UNITmV mThemNeurologicmSystem
15 Structuremand mFunctionmof mthemNeurologicmSystem
16 Pain,mTemperaturemRegulation,mSleep,mand mSensorymFunction
17AlterationsminmCognitivemSystems,mCerebralmHemodynamics,mand mMotormFunction
18 Alterationsmof mthemBrain,mSpinalmCord,mand mPeripheralmNerves
19 Neurobiologymof mSchizophrenia,mMood mDisorders,mAnxietymDisorders,mPosttraumaticmStre
ssmDisorder,mand mobsessive-compulsivemdisorder
20 Alterationsmof mNeurologicmFunctionminmChildren
UNITmVImThemEndocrinemSystem
21 Mechanismsmof mHormonalmRegulation
22 Alterationsmof mHormonalmRegulation
23 Obesity,mStarvation,mand mAnorexiamof mAging
UNITmVIImThemReproductivemSystems
24 Structuremand mFunctionmof mthemReproductivemSystems
25 Alterationsmof mthemFemalemReproductivemSystem
26 Alterationsmof mthemMalemReproductivemSystem
27 SexuallymTransmitted mInfections
UNITmVIIImThemHematologicmSystem
28 Structuremand mFunctionmof mthemHematologicmSystem
29 Alterationsmof mHematologicmFunction
30 Alterationsmof mHematologicmFunctionminmChildren
UNITmIX mThemCardiovascularmandmLymphaticmSystems
,31 Structuremand mFunctionmof mthemCardiovascularmand mLymphaticmSystems
32 Alterationsmof mCardiovascularmFunction
33 Alterationsmof mCardiovascularmFunctionminmChildren
,UNITmX mThemPulmonarymSystem
34 Structuremand mFunctionmof mthemPulmonarymSystem
35 Alterationsmof mPulmonarymFunction
36 Alterationsmof mPulmonarymFunctionminmChildren
UNITmXImThemRenalmandmUrologicmSystems
37 Structuremand mFunctionmof mthemRenalmand mUrologicmSystems
38 Alterationsmof mRenalmand mUrinarymTract mFunction
39 Alterationsmof mRenalmand mUrinarymTract mFunctionminmChildren
UNITmXIImThemDigestivemSystem
40 Structuremand mFunctionmof mthemDigestivemSystem,m1285
41 Alterationsmof mDigestivemFunction
42 Alterationsmof mDigestivemFunctionminmChildren
UNITmXIIImThemMusculoskeletalmSystem
43 Structuremand mFunctionmof mthemMusculoskeletalmSystem
44 Alterationsmof mMusculoskeletalmFunction
45 Alterationsmof mMusculoskeletalmFunctionminmChildren
UNITmXIV mThemIntegumentarymSystem
46 Structure,mFunction,mand mDisordersmof mthemIntegument
47 Alterationsmof mthemIntegument minmChildren
UNITmXV mMultiplemInteractingmSystems
48 Shock,mMultiplemOrganmDysfunctionmSyndrome,mand mBurnsminmAdults
49 Shock,mMultiplemOrganmChapterm1:mCellularmBiology
MULTIPLEmCHOICE
1. Whichmstatement mbest mdescribesmthemcellularmfunctionmof mmetabolicmabsorption?
a. Cellsmcanmproducemproteins. c. Cellsmcanmtakeminmand musemnutrients.
b. Cellsmcanmsecretemdigestivemenzymes. d.m Cellsmcanmsynthesizemfats.
ANS:m C
Inmmetabolicmabsorption,mallmcellsmtakeminmand musemnutrientsmand mothermsubstancesmfrommthei
rmsurroundings.mThemremainingmoptionsmare mnot minclusivem inmtheirmdescriptionsmof mcellular m
metabolicmabsorption.
PTS:m m 1 REF:m Pagem2
2. Most mof mamcell’smgeneticminformation,mincludingmRNA mand mDNA,mismcontained minmthe:
a. Mitochondria c. Nucleolus
b. Ribosome d.m m Lysosome
ANS:m C
Themnucleusmcontainsmthemnucleolus,mamsmallmdensemstructuremcomposed mlargelymof mRNA,m
most mof mthemcellularmDNA,mand mthemDNA-
bindingmproteins,msuchmasmthemhistones,mwhichmregulatemitsmactivity.mThemothermoptionsmdomn
ot mcontainmmost mof mamcell’smgeneticminformation.
PTS:m m 1 REF:m Pagem2
3. Whichmcomponentmofmthemcellmp rodNuUc eRsS mIhNy Gd Tr oB g. mCe nO mMpmeroxidem (H2O2)mbymusingmoxyge
nmtomremovemhydrogenmatomsmfrommspecificmsubstratesminmanmoxidativemreaction?
a. Lysosomes c. Ribosomes
b. Peroxisomes d.m Oxyhydrosomes
ANS:m B
, Peroxisomesmaremsomnamed mbecausemtheymusuallymcontainmenzymes mthat musemoxygenmtomre
movemhydrogenmatomsmfrommspecificmsubstratesminmanmoxidativemreactionmthat mproducesmH2
O 2 ,mwhichmismampowerfulmoxidant mand mpotentiallymdestructivemif mit maccumulatesmormescapesm
frommperoxisomes.mRibosomesmaremRNA-
proteinmcomplexesm(nucleoproteins)mthat maremsynthesized minmthemnucleolusmand msecreted mint
omthemcytoplasmmthroughmporesminmthemnuclearmenvelopemcalled mnuclearmporemcomplexes. mL
ysosomesmaremsaclikemstructuresmthat moriginatemfrommthemGolgimcomplex mand mcontainmmore
mthanm40mdigestivemenzymesmcalled mhydrolases,mwhichmcatalyzembondsminmproteins,mlipids,mn
ucleicmacids,mand mcarbohydrates.mOxyhydrosomesmareminvolved minmenzymemproduction.
PTS:m m 1 REF:m Pagem8
4. Whichmcellmcomponent mismcapablemof mcellularmautodigestionmwhenmit mis mreleased mduringmc
ellminjury?
a. Ribosome c. Smoothmendoplasmicmreticulum
b. Golgimcomplex d.m Lysosomes
ANS:m D