Radiation Therapy Chapter 1 Questions with
Verified Solutions| Latest Update
1. Which classification of chemotherapy agents was the first to be identified as having
anticancer activities?
a. Alkylating agents
b. Antimetabolites
c. Antibiotics
d. Hormonal agents
e. Nitrosoureas
f. Vinca alkaloids A
The first chemotherapy agent was nitrous mustard, an alkylating agent.
p. 12
2. Which of the following are not cell cycles specific?
I. Alkylating agents
II. Antimetabolites
III. Antibiotics
IV. Hormonal agents
V. Nitrosoureas
VI. Vinca alkaloids
a. I and II
b. I and III
c. I, III, and V
d. II, IV, and VI
e. II, III, and VI C
,Alkylating agents are not cell cycle specific. Neither are anticancer antibiotics (although they are
more effective during certain phases) nor nitrosoureas.
p. 12
3. Which classification of chemotherapy agents is derived from the periwinkle plant?
a. Alkylating agents
b. Antimetabolites
c. Antibiotics
d. Hormonal agents
e. Nitrosoureas
f. Vinca alkaloids F
Periwinkle plants are part of the genus Vinca and are sometimes called vinca. It is from these
plants that vinca alkaloids are derived.
p. 12
4. In which classification are the chemotherapy agent's lipids soluble and capable of crossing
the blood-brain barrier?
a. Alkylating agents
b. Antimetabolites
c. Antibiotics
d. Hormonal agents
e. Nitrosoureas
f. Vinca alkaloids E
Nitrosoureas are the only classification of chemotherapy agents that are both lipid soluble and
capable of passing through the blood-brain barrier.
, p. 12
5. Which of the following is a radiosensitizing chemotherapy agent?
a. Cyclophosphamide
b. 5-Fluorouracil
c. Doxorubicin
d. Cisplatin C
Doxorubicin, also known as Adriamycin, acts a radiosensitizer. Cyclophosphamide, 5-
fluorouracil, and cisplatin are not known to enhance the effects of radiation.
p. 14
6. Which of the following acts as a radioprotector?
a. Amifostine
b. Actinomycin D
c. Adriamycin
d. Etoposide A
Amifostine acts to protect normal tissue against the effects of radiation and is, therefore,
considered a radioprotector. Adriamycin is a radiosensitizer. Actinomycin and etoposide are not
known to be radioprotectors.
p. 14
37. Injecting monoclonal antibodies is an example of which type of treatment?
a. Surgery
b. Radiation therapy
c. Chemotherapy
d. Immunotherapy D
Verified Solutions| Latest Update
1. Which classification of chemotherapy agents was the first to be identified as having
anticancer activities?
a. Alkylating agents
b. Antimetabolites
c. Antibiotics
d. Hormonal agents
e. Nitrosoureas
f. Vinca alkaloids A
The first chemotherapy agent was nitrous mustard, an alkylating agent.
p. 12
2. Which of the following are not cell cycles specific?
I. Alkylating agents
II. Antimetabolites
III. Antibiotics
IV. Hormonal agents
V. Nitrosoureas
VI. Vinca alkaloids
a. I and II
b. I and III
c. I, III, and V
d. II, IV, and VI
e. II, III, and VI C
,Alkylating agents are not cell cycle specific. Neither are anticancer antibiotics (although they are
more effective during certain phases) nor nitrosoureas.
p. 12
3. Which classification of chemotherapy agents is derived from the periwinkle plant?
a. Alkylating agents
b. Antimetabolites
c. Antibiotics
d. Hormonal agents
e. Nitrosoureas
f. Vinca alkaloids F
Periwinkle plants are part of the genus Vinca and are sometimes called vinca. It is from these
plants that vinca alkaloids are derived.
p. 12
4. In which classification are the chemotherapy agent's lipids soluble and capable of crossing
the blood-brain barrier?
a. Alkylating agents
b. Antimetabolites
c. Antibiotics
d. Hormonal agents
e. Nitrosoureas
f. Vinca alkaloids E
Nitrosoureas are the only classification of chemotherapy agents that are both lipid soluble and
capable of passing through the blood-brain barrier.
, p. 12
5. Which of the following is a radiosensitizing chemotherapy agent?
a. Cyclophosphamide
b. 5-Fluorouracil
c. Doxorubicin
d. Cisplatin C
Doxorubicin, also known as Adriamycin, acts a radiosensitizer. Cyclophosphamide, 5-
fluorouracil, and cisplatin are not known to enhance the effects of radiation.
p. 14
6. Which of the following acts as a radioprotector?
a. Amifostine
b. Actinomycin D
c. Adriamycin
d. Etoposide A
Amifostine acts to protect normal tissue against the effects of radiation and is, therefore,
considered a radioprotector. Adriamycin is a radiosensitizer. Actinomycin and etoposide are not
known to be radioprotectors.
p. 14
37. Injecting monoclonal antibodies is an example of which type of treatment?
a. Surgery
b. Radiation therapy
c. Chemotherapy
d. Immunotherapy D
