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Edition Abbas
Abbas: Cellular and Molecular Immunology, 9th Edition
Antibodies and Antigens
Test Bank
Matching
Questions 1-5
Match each of the descriptions in questions 1-5 with the correct lettered antibody isotype
(A-E). (Answers may be used more than once.)
A. IgA
B. IgD
C. IgE
D. IgG
E. IgM
1. The secreted form of this isotype forms pentamers around a J chain
ANS: E. IgM is secreted as a J chain–linked pentamer.
2. The most abundant Ig isotype in the blood
ANS: D. The blood IgG concentration is about 3.5 mg/mL and includes four subtypes
(IgG1 to IgG4).
3. The isotype only found in membrane-bound form on naive B cells
ANS: B. Very little IgD is secreted, and in membrane form is only on the surface of naive
B cells. Its function is not well understood.
4. The isotype found predominantly in mucosal secretions
ANS: A. IgA accounts for almost two thirds of the 3 g of antibody produced each day by
an adult, most of which is produced in the gastrointestinal associated lymphoid tissues
and secreted into the gut lumen.
5. The isotype most closely associated with immediate hypersensitivity (allergic)
disease
ANS: C. Most IgE that is secreted is bound to mast cells, and it plays a role in the
activation of mast cells during allergic reactions.
Questions 6-10
Match each description in questions 6-10 with the appropriate lettered term (A-I).
A. Conformational determinant
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B. Linear determinant Taxonomy: Recall
C. Neoantigenic determinant
D. Hinge region 3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is
E. Immun complex
unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet
F. Fab experienced the negative health consequences of his actions, he cannot be classified as resistant.
G. Fc Ans: False
H. Tail piece Complexity: Moderate
I. Hapten Ahead: Interviewing
Subject: Chapter 1
Title: Interview and History-Taking Strategies
download full chapter
6. A proteolytic fragment of an antibody molecule that contains an intact antigen- Taxonomy: Application
binding site
ANS: F. Fab fragments, derived from enzymatic cleavage of Ig molecules, are composed 4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard
of one intact light chain covalently linked to the N-terminal region of one heavy chain medical terminology for clarity.
and include a single intact antigen-binding site. Ans: False
Complexity: Easy
7. A three-dimensional shape, formed by a portion of a macromolecule, to which an Ahead: Taking a Health History
Subject: Chapter 1
antibody binds Title: Interview and History-Taking Strategies
Taxonomy: Recall
ANS: A. Conformational determinants will usually be destroyed by physicochemical
disruption of macromolecules, such as by denaturation or proteolysis of proteins.
5. True or False? Family history should include both parents and grandparents, if information is known.
8. A small chemical group recognized by an antibody that is attached to a larger Ans: True
macromolecule Complexity: Moderate
Ahead: Taking a Health History
Subject: Chapter 1
ANS: I. Although haptens can be recognized by antibodies, they are not, by themselves, Title: Interview and History-Taking Strategies
able to stimulate an antibody response (i.e., they are not immunogens). Antibody Taxonomy: Application
responses to haptens can be induced when the hapten is attached to a macromolecule,
called a carrier.
6. True or False? Social history includes a detailed diet history, best performed as a record of food and
9. The proteolytic fragment of an antibody molecule that contains the heavy chain
beverage intake by the patient for a typical week, that includes things like use of salt and oil in food
constant region preparation and methods of cooking.
Ans: True
ANS: G. The Fc fragment, generated by proteolytic cleavage of an antibody molecule, is Complexity: Moderate
composed of the C-terminal end of the heavy chain and lacks the antigen-binding region. Ahead: Taking a Health History
Subject: Chapter 1
This region of an intact Ig molecule, which can interact with Ig receptors and Title: Interview and History-Taking Strategies
complement, is called the Fc region. Taxonomy: Application
10. A region of an antibody molecule that permits bivalent binding of antibodies to pairs
of surface epitopes varying in distance from one another
ANS: D. The hinge region, located between the two N-terminal Ig domains of the heavy Essay
chains of most isotypes, is flexible, permitting variations in the distance between the two
antigen-binding sites.
1. What does PQRST stand for?
Ans: Precipitating factors, quality, radiation, severity, and timing
Complexity: Difficult
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Taxonomy: Recall Taxonomy: Recall
3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is 3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is
unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet
experienced the negative health consequences of his actions, he cannot be classified as resistant. experienced the negative health consequences of his actions, he cannot be classified as resistant.
Ans: False Ans: False
Complexity: Moderate Complexity: Moderate
Ahead: Interviewing Ahead: Interviewing
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
download full chapter download full chapter
Taxonomy: Application Taxonomy: Application
4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard 4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard
medical terminology for clarity. medical terminology for clarity.
Ans: False Ans: False
Complexity: Easy Complexity: Easy
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Recall Taxonomy: Recall
5. True or False? Family history should include both parents and grandparents, if information is known. 5. True or False? Family history should include both parents and grandparents, if information is known.
Ans: True Ans: True
Complexity: Moderate Complexity: Moderate
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Application Taxonomy: Application
6. True or False? Social history includes a detailed diet history, best performed as a record of food and 6. True or False? Social history includes a detailed diet history, best performed as a record of food and
beverage intake by the patient for a typical week, that includes things like use of salt and oil in food beverage intake by the patient for a typical week, that includes things like use of salt and oil in food
preparation and methods of cooking. preparation and methods of cooking.
Ans: True Ans: True
Complexity: Moderate Complexity: Moderate
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Application Taxonomy: Application
Essay Essay
1. What does PQRST stand for? 1. What does PQRST stand for?
Ans: Precipitating factors, quality, radiation, severity, and timing Ans: Precipitating factors, quality, radiation, severity, and timing
Complexity: Difficult Complexity: Difficult
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, Advanced Health Assessment and Diagnostic Reasoning, Third Edition Advanced Health Assessment and Diagnostic Reasoning, Third Edition
Test Bank Test Bank
Taxonomy: Recall Taxonomy: Recall
3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is 3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is
unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet
experienced the negative health consequences of his actions, he cannot be classified as resistant. experienced the negative health consequences of his actions, he cannot be classified as resistant.
Ans: False Ans: False
Complexity: Moderate Complexity: Moderate
Ahead: Interviewing Ahead: Interviewing
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
download full chapter download full chapter
Taxonomy: Application Taxonomy: Application
4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard 4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard
medical terminology for clarity. medical terminology for clarity.
Ans: False Ans: False
Complexity: Easy Complexity: Easy
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Recall Taxonomy: Recall
5. True or False? Family history should include both parents and grandparents, if information is known. 5. True or False? Family history should include both parents and grandparents, if information is known.
Ans: True Ans: True
Complexity: Moderate Complexity: Moderate
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Application Taxonomy: Application
6. True or False? Social history includes a detailed diet history, best performed as a record of food and 6. True or False? Social history includes a detailed diet history, best performed as a record of food and
beverage intake by the patient for a typical week, that includes things like use of salt and oil in food beverage intake by the patient for a typical week, that includes things like use of salt and oil in food
preparation and methods of cooking. preparation and methods of cooking.
Ans: True Ans: True
Complexity: Moderate Complexity: Moderate
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Application Taxonomy: Application
Essay Essay
1. What does PQRST stand for? 1. What does PQRST stand for?
Ans: Precipitating factors, quality, radiation, severity, and timing Ans: Precipitating factors, quality, radiation, severity, and timing
Complexity: Difficult Complexity: Difficult
Copyright © 2018 Jones & Bartlett Learning, LLC, as Ascend Learning Company Copyright © 2018 Jones & Bartlett Learning, LLC, as Ascend Learning Company
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Edition Abbas
Abbas: Cellular and Molecular Immunology, 9th Edition
Antibodies and Antigens
Test Bank
Matching
Questions 1-5
Match each of the descriptions in questions 1-5 with the correct lettered antibody isotype
(A-E). (Answers may be used more than once.)
A. IgA
B. IgD
C. IgE
D. IgG
E. IgM
1. The secreted form of this isotype forms pentamers around a J chain
ANS: E. IgM is secreted as a J chain–linked pentamer.
2. The most abundant Ig isotype in the blood
ANS: D. The blood IgG concentration is about 3.5 mg/mL and includes four subtypes
(IgG1 to IgG4).
3. The isotype only found in membrane-bound form on naive B cells
ANS: B. Very little IgD is secreted, and in membrane form is only on the surface of naive
B cells. Its function is not well understood.
4. The isotype found predominantly in mucosal secretions
ANS: A. IgA accounts for almost two thirds of the 3 g of antibody produced each day by
an adult, most of which is produced in the gastrointestinal associated lymphoid tissues
and secreted into the gut lumen.
5. The isotype most closely associated with immediate hypersensitivity (allergic)
disease
ANS: C. Most IgE that is secreted is bound to mast cells, and it plays a role in the
activation of mast cells during allergic reactions.
Questions 6-10
Match each description in questions 6-10 with the appropriate lettered term (A-I).
A. Conformational determinant
Copyright © 2018, Elsevier Inc. All rights reserved.
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Edition Abbas
Test Bank 2 Advanced Health Assessment and Diagnostic Reasoning, Third Edition
Test Bank
B. Linear determinant Taxonomy: Recall
C. Neoantigenic determinant
D. Hinge region 3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is
E. Immun complex
unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet
F. Fab experienced the negative health consequences of his actions, he cannot be classified as resistant.
G. Fc Ans: False
H. Tail piece Complexity: Moderate
I. Hapten Ahead: Interviewing
Subject: Chapter 1
Title: Interview and History-Taking Strategies
download full chapter
6. A proteolytic fragment of an antibody molecule that contains an intact antigen- Taxonomy: Application
binding site
ANS: F. Fab fragments, derived from enzymatic cleavage of Ig molecules, are composed 4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard
of one intact light chain covalently linked to the N-terminal region of one heavy chain medical terminology for clarity.
and include a single intact antigen-binding site. Ans: False
Complexity: Easy
7. A three-dimensional shape, formed by a portion of a macromolecule, to which an Ahead: Taking a Health History
Subject: Chapter 1
antibody binds Title: Interview and History-Taking Strategies
Taxonomy: Recall
ANS: A. Conformational determinants will usually be destroyed by physicochemical
disruption of macromolecules, such as by denaturation or proteolysis of proteins.
5. True or False? Family history should include both parents and grandparents, if information is known.
8. A small chemical group recognized by an antibody that is attached to a larger Ans: True
macromolecule Complexity: Moderate
Ahead: Taking a Health History
Subject: Chapter 1
ANS: I. Although haptens can be recognized by antibodies, they are not, by themselves, Title: Interview and History-Taking Strategies
able to stimulate an antibody response (i.e., they are not immunogens). Antibody Taxonomy: Application
responses to haptens can be induced when the hapten is attached to a macromolecule,
called a carrier.
6. True or False? Social history includes a detailed diet history, best performed as a record of food and
9. The proteolytic fragment of an antibody molecule that contains the heavy chain
beverage intake by the patient for a typical week, that includes things like use of salt and oil in food
constant region preparation and methods of cooking.
Ans: True
ANS: G. The Fc fragment, generated by proteolytic cleavage of an antibody molecule, is Complexity: Moderate
composed of the C-terminal end of the heavy chain and lacks the antigen-binding region. Ahead: Taking a Health History
Subject: Chapter 1
This region of an intact Ig molecule, which can interact with Ig receptors and Title: Interview and History-Taking Strategies
complement, is called the Fc region. Taxonomy: Application
10. A region of an antibody molecule that permits bivalent binding of antibodies to pairs
of surface epitopes varying in distance from one another
ANS: D. The hinge region, located between the two N-terminal Ig domains of the heavy Essay
chains of most isotypes, is flexible, permitting variations in the distance between the two
antigen-binding sites.
1. What does PQRST stand for?
Ans: Precipitating factors, quality, radiation, severity, and timing
Complexity: Difficult
Copyright © 2018, Elsevier Inc. All rights reserved. Copyright © 2018 Jones & Bartlett Learning, LLC, as Ascend Learning Company
mynursytest.store
bundigital.store
,Advanced Health Assessment and Diagnostic Reasoning, Third Edition Advanced Health Assessment and Diagnostic Reasoning, Third Edition
Test Bank Test Bank
Taxonomy: Recall Taxonomy: Recall
3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is 3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is
unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet
experienced the negative health consequences of his actions, he cannot be classified as resistant. experienced the negative health consequences of his actions, he cannot be classified as resistant.
Ans: False Ans: False
Complexity: Moderate Complexity: Moderate
Ahead: Interviewing Ahead: Interviewing
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
download full chapter download full chapter
Taxonomy: Application Taxonomy: Application
4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard 4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard
medical terminology for clarity. medical terminology for clarity.
Ans: False Ans: False
Complexity: Easy Complexity: Easy
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Recall Taxonomy: Recall
5. True or False? Family history should include both parents and grandparents, if information is known. 5. True or False? Family history should include both parents and grandparents, if information is known.
Ans: True Ans: True
Complexity: Moderate Complexity: Moderate
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Application Taxonomy: Application
6. True or False? Social history includes a detailed diet history, best performed as a record of food and 6. True or False? Social history includes a detailed diet history, best performed as a record of food and
beverage intake by the patient for a typical week, that includes things like use of salt and oil in food beverage intake by the patient for a typical week, that includes things like use of salt and oil in food
preparation and methods of cooking. preparation and methods of cooking.
Ans: True Ans: True
Complexity: Moderate Complexity: Moderate
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Application Taxonomy: Application
Essay Essay
1. What does PQRST stand for? 1. What does PQRST stand for?
Ans: Precipitating factors, quality, radiation, severity, and timing Ans: Precipitating factors, quality, radiation, severity, and timing
Complexity: Difficult Complexity: Difficult
Copyright © 2018 Jones & Bartlett Learning, LLC, as Ascend Learning Company Copyright © 2018 Jones & Bartlett Learning, LLC, as Ascend Learning Company
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, Advanced Health Assessment and Diagnostic Reasoning, Third Edition Advanced Health Assessment and Diagnostic Reasoning, Third Edition
Test Bank Test Bank
Taxonomy: Recall Taxonomy: Recall
3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is 3. True or False? A 58-year-old man at risk of diabetes, with a sedentary lifestyle and unhealthy diet, is
unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet unwilling to follow his provider’s recommendations to modify his routine. Because he has not yet
experienced the negative health consequences of his actions, he cannot be classified as resistant. experienced the negative health consequences of his actions, he cannot be classified as resistant.
Ans: False Ans: False
Complexity: Moderate Complexity: Moderate
Ahead: Interviewing Ahead: Interviewing
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
download full chapter download full chapter
Taxonomy: Application Taxonomy: Application
4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard 4. True or False? When taking a patient’s chief complaint, rephrase the stated reason using standard
medical terminology for clarity. medical terminology for clarity.
Ans: False Ans: False
Complexity: Easy Complexity: Easy
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Recall Taxonomy: Recall
5. True or False? Family history should include both parents and grandparents, if information is known. 5. True or False? Family history should include both parents and grandparents, if information is known.
Ans: True Ans: True
Complexity: Moderate Complexity: Moderate
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Application Taxonomy: Application
6. True or False? Social history includes a detailed diet history, best performed as a record of food and 6. True or False? Social history includes a detailed diet history, best performed as a record of food and
beverage intake by the patient for a typical week, that includes things like use of salt and oil in food beverage intake by the patient for a typical week, that includes things like use of salt and oil in food
preparation and methods of cooking. preparation and methods of cooking.
Ans: True Ans: True
Complexity: Moderate Complexity: Moderate
Ahead: Taking a Health History Ahead: Taking a Health History
Subject: Chapter 1 Subject: Chapter 1
Title: Interview and History-Taking Strategies Title: Interview and History-Taking Strategies
Taxonomy: Application Taxonomy: Application
Essay Essay
1. What does PQRST stand for? 1. What does PQRST stand for?
Ans: Precipitating factors, quality, radiation, severity, and timing Ans: Precipitating factors, quality, radiation, severity, and timing
Complexity: Difficult Complexity: Difficult
Copyright © 2018 Jones & Bartlett Learning, LLC, as Ascend Learning Company Copyright © 2018 Jones & Bartlett Learning, LLC, as Ascend Learning Company
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