lOMoAR cPSD| 21007614
Pharmacotherapeutics for Advanced Practice- A
PracticalApproach 5th Edition Arcangelo Test Bank
, lOMoAR cPSD| 21007614
Chapter 1 Issues for the Practitioner in Drug Therapy
nj nj nj nj nj nj nj nj
MULTIPLE CHOICE nj
1. Nurse practitioner prescriptive authority is regulated by:
nj nj nj nj nj nj
A. The National Council of State Boards of Nursing
nj nj nj nj nj nj nj
B. The U.S. Drug Enforcement Administration
nj nj nj nj
C. The State Board of Nursing for each state
nj nj nj nj nj nj nj
D. The State Board of Pharmacy
nj nj nj nj
ANS: n j C PTS: n j 1
2. Physician Assistant (PA) prescriptive authority is regulated by:
nj nj nj nj nj nj nj
A. The National Council of State Boards of Nursing
nj nj nj nj nj nj nj
B. The U.S. Drug Enforcement Administration
nj nj nj nj
C. The State Board of Nursing
nj nj nj nj
D. The State Board of Medical Examiners
nj nj nj nj nj
ANS: n j D PTS: n j 1
3. Clinical judgment in prescribing includes:
nj nj nj nj
A. Factoring in the cost to the patient of the medication prescribed
nj nj nj nj nj nj nj nj nj nj
B. Always prescribing the newest medication available for the disease process
nj nj nj nj nj nj nj nj nj
C. Handing out drug samples to poor patients nj nj nj nj nj nj
D. Prescribing all generic medications to cut costs nj nj nj nj nj nj
ANS: n j A PTS: n j 1
4. Criteria for choosing an effective drug for a disorder include:
nj nj nj nj nj nj nj nj nj
A. Asking the patient what drug they think would work best for them
nj nj nj nj nj nj nj nj nj nj nj
B. Consulting nationally recognized guidelines for disease managementnj nj nj nj nj nj
C. Prescribing medications that are available as samples before writing a prescription
nj nj nj nj nj nj nj nj nj nj
D. Following U.S. Drug Enforcement Administration (DEA) guidelines
nj nj nj nj nj nj
nj forprescribing
nj
ANS: n j B PTS: n j 1
5. Nurse practitioner practice may thrive under health-care reform due to:
nj nj nj nj nj nj nj nj nj
A. The demonstrated ability of nurse practitioners to control costs and improve
nj nj nj nj nj nj nj nj nj nj
nj patientoutcomes nj
B. The fact that nurse practitioners will be able to practice independently
nj nj nj nj nj nj nj nj nj nj
C. The fact that nurse practitioners will have full reimbursement under health-
nj nj nj nj nj nj nj nj nj nj
carereform nj
D. The ability to shift accountability for Medicaid to the state level
nj nj nj nj nj nj nj nj nj nj
ANS: n j A PTS: n j 1
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()
nj
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Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
nj nj nj nj nj nj
MULTIPLE CHOICE nj
1. A patient's nutritional intake and lab work reflects hypoalbuminemia. This is critical
nj nj nj nj nj nj nj nj nj nj nj
toprescribing because:
nj nj nj
A. Distribution of drugs to target tissue may be affected nj nj nj nj nj nj nj nj
B. The solubility of the drug will not match the site of absorption
nj nj nj nj nj nj nj nj nj nj nj
C. There will be less free drug available to generate an effect
nj nj nj nj nj nj nj nj nj nj
D. Drugs bound to albumin are readily excreted by the kidney
nj nj nj nj nj nj nj nj nj
ANS: n j A PTS: n j 1
2. Drugs that have a significant first-pass effect:
nj nj nj nj nj nj
A. Must be given by the enteral (oral) route only
nj nj nj nj nj nj nj nj
B. Bypass the hepatic circulation nj nj nj
C. Are rapidly metabolized by the liver and may have little if any desired action
nj nj nj nj nj nj nj nj nj nj nj nj nj
D. Are converted by the liver to more active and fat-soluble forms
nj nj nj nj nj nj nj nj nj nj
ANS: n j C PTS: n j 1
3. The route of excretion of a volatile drug will likely be:
nj nj nj nj nj nj nj nj nj nj
A. The kidneys nj
B. The lungs nj
C. The bile and feces nj nj nj
D. The skin nj
ANS: n j B PTS: n j 1
4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of nj nj nj nj nj nj nj nj nj nj nj
thedrug. Storage reservoirs:
nj nj nj nj
A. Assure that the drug will reach its intended target tissue
nj nj nj nj nj nj nj nj nj
B. Are the reason for giving loading doses
nj nj nj nj nj nj
C. Increase the length of time a drug is available and active nj nj nj nj nj nj nj nj nj nj
D. Are most common in collagen tissues
nj nj nj nj nj
ANS: n j C PTS: n j 1
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
nj nj nj nj nj nj nj nj nj nj nj nj nj nj
A. Propensity to go to the target receptor nj nj nj nj nj nj
B. Biological half-life nj
C. Pharmacodynamics
D. Safety and side effects nj nj nj
ANS: n j B PTS: n j 1
6. Azithromycin dosing requires the first day's dose be twice those of the other 4 days of
nj nj nj nj nj nj nj nj nj nj nj nj nj nj nj
theprescription. This is considered a loading dose. A loading dose:
nj nj nj nj nj nj nj nj nj nj nj
A. Rapidly achieves drug levels in the therapeutic range nj nj nj nj nj nj nj
B. Requires four to five half-lives to attain nj nj nj nj nj nj
C. Is influenced by renal function
nj nj nj nj
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nj
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D. Is directly related to the drug circulating to the target tissues
nj nj nj nj nj nj nj nj nj nj
ANS: n j A PTS: nj nj n j 1
7. The point in time on the drug concentration curve that indicates the first sign of a
nj nj nj nj nj nj nj nj nj nj nj nj nj nj nj
therapeuticeffect is the:
nj nj nj nj
A. Minimum adverse effect level nj nj nj
B. Peak of action nj nj
C. Onset of action nj nj
D. Therapeutic range nj
ANS: n j C PTS: n j 1
8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
nj nj nj nj nj nj nj nj nj nj nj nj
A. When the drug has a wide therapeutic range nj nj nj nj nj nj nj
B. When the drug will be administered for a short time only
nj nj nj nj nj nj nj nj nj nj
C. When there is a high correlation between the dose and saturation of receptor sites
nj nj nj nj nj nj nj nj nj nj nj nj nj
D. To determine if a drug is in the therapeutic range
nj nj nj nj nj nj nj nj nj
ANS: n j D PTS: n j 1
9. A laboratory result indicates the peak level for a drug is above the minimum
nj nj nj nj nj nj nj nj nj nj nj nj nj
toxicconcentration. This means that the:
nj nj nj nj nj nj
A. Concentration will produce therapeutic effects nj nj nj nj
B. Concentration will produce an adverse response nj nj nj nj nj
C. Time between doses must be shortened nj nj nj nj nj
D. Duration of action of the drug is too long nj nj nj nj nj nj nj nj
ANS: n j B PTS: n j 1
10. Drugs that are receptor agonists may demonstrate what property?
nj nj nj nj nj nj nj nj
A. Irreversible binding to the drug receptor site nj nj nj nj nj nj
B. Up-regulation with chronic use nj nj nj
C. Desensitization or down-regulation with continuous use nj nj nj nj nj
D. Inverse relationship between drug concentration and drug action
nj nj nj nj nj nj nj
ANS: n j C PTS: n j 1
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
nj nj nj nj nj nj nj nj nj nj
A. Down-regulation of the drug receptor nj nj nj nj
B. An exaggerated response if abruptly discontinued
nj nj nj nj nj
C. Partial blockade of the effects of agonist drugs nj nj nj nj nj nj nj
D. An exaggerated response to competitive drug agonists
nj nj nj nj nj nj
ANS: n j B PTS: n j 1
12. Factors that affect gastric drug absorption include:
nj nj nj nj nj nj
A. Liver enzyme activity nj nj
B. Protein-binding properties of the drug molecule nj nj nj nj nj
C. Lipid solubility of the drug nj nj nj nj
D. Ability to chew and swallow nj nj nj nj
ANS: n j C PTS: n j 1
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Downloaded by Patrick Liquete nj nj nj
()
nj
Pharmacotherapeutics for Advanced Practice- A
PracticalApproach 5th Edition Arcangelo Test Bank
, lOMoAR cPSD| 21007614
Chapter 1 Issues for the Practitioner in Drug Therapy
nj nj nj nj nj nj nj nj
MULTIPLE CHOICE nj
1. Nurse practitioner prescriptive authority is regulated by:
nj nj nj nj nj nj
A. The National Council of State Boards of Nursing
nj nj nj nj nj nj nj
B. The U.S. Drug Enforcement Administration
nj nj nj nj
C. The State Board of Nursing for each state
nj nj nj nj nj nj nj
D. The State Board of Pharmacy
nj nj nj nj
ANS: n j C PTS: n j 1
2. Physician Assistant (PA) prescriptive authority is regulated by:
nj nj nj nj nj nj nj
A. The National Council of State Boards of Nursing
nj nj nj nj nj nj nj
B. The U.S. Drug Enforcement Administration
nj nj nj nj
C. The State Board of Nursing
nj nj nj nj
D. The State Board of Medical Examiners
nj nj nj nj nj
ANS: n j D PTS: n j 1
3. Clinical judgment in prescribing includes:
nj nj nj nj
A. Factoring in the cost to the patient of the medication prescribed
nj nj nj nj nj nj nj nj nj nj
B. Always prescribing the newest medication available for the disease process
nj nj nj nj nj nj nj nj nj
C. Handing out drug samples to poor patients nj nj nj nj nj nj
D. Prescribing all generic medications to cut costs nj nj nj nj nj nj
ANS: n j A PTS: n j 1
4. Criteria for choosing an effective drug for a disorder include:
nj nj nj nj nj nj nj nj nj
A. Asking the patient what drug they think would work best for them
nj nj nj nj nj nj nj nj nj nj nj
B. Consulting nationally recognized guidelines for disease managementnj nj nj nj nj nj
C. Prescribing medications that are available as samples before writing a prescription
nj nj nj nj nj nj nj nj nj nj
D. Following U.S. Drug Enforcement Administration (DEA) guidelines
nj nj nj nj nj nj
nj forprescribing
nj
ANS: n j B PTS: n j 1
5. Nurse practitioner practice may thrive under health-care reform due to:
nj nj nj nj nj nj nj nj nj
A. The demonstrated ability of nurse practitioners to control costs and improve
nj nj nj nj nj nj nj nj nj nj
nj patientoutcomes nj
B. The fact that nurse practitioners will be able to practice independently
nj nj nj nj nj nj nj nj nj nj
C. The fact that nurse practitioners will have full reimbursement under health-
nj nj nj nj nj nj nj nj nj nj
carereform nj
D. The ability to shift accountability for Medicaid to the state level
nj nj nj nj nj nj nj nj nj nj
ANS: n j A PTS: n j 1
WWW.TEGTBANKTANK.COM
Downloaded by Patrick Liquete nj nj nj
()
nj
, lOMoAR cPSD| 21007614
Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
nj nj nj nj nj nj
MULTIPLE CHOICE nj
1. A patient's nutritional intake and lab work reflects hypoalbuminemia. This is critical
nj nj nj nj nj nj nj nj nj nj nj
toprescribing because:
nj nj nj
A. Distribution of drugs to target tissue may be affected nj nj nj nj nj nj nj nj
B. The solubility of the drug will not match the site of absorption
nj nj nj nj nj nj nj nj nj nj nj
C. There will be less free drug available to generate an effect
nj nj nj nj nj nj nj nj nj nj
D. Drugs bound to albumin are readily excreted by the kidney
nj nj nj nj nj nj nj nj nj
ANS: n j A PTS: n j 1
2. Drugs that have a significant first-pass effect:
nj nj nj nj nj nj
A. Must be given by the enteral (oral) route only
nj nj nj nj nj nj nj nj
B. Bypass the hepatic circulation nj nj nj
C. Are rapidly metabolized by the liver and may have little if any desired action
nj nj nj nj nj nj nj nj nj nj nj nj nj
D. Are converted by the liver to more active and fat-soluble forms
nj nj nj nj nj nj nj nj nj nj
ANS: n j C PTS: n j 1
3. The route of excretion of a volatile drug will likely be:
nj nj nj nj nj nj nj nj nj nj
A. The kidneys nj
B. The lungs nj
C. The bile and feces nj nj nj
D. The skin nj
ANS: n j B PTS: n j 1
4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of nj nj nj nj nj nj nj nj nj nj nj
thedrug. Storage reservoirs:
nj nj nj nj
A. Assure that the drug will reach its intended target tissue
nj nj nj nj nj nj nj nj nj
B. Are the reason for giving loading doses
nj nj nj nj nj nj
C. Increase the length of time a drug is available and active nj nj nj nj nj nj nj nj nj nj
D. Are most common in collagen tissues
nj nj nj nj nj
ANS: n j C PTS: n j 1
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
nj nj nj nj nj nj nj nj nj nj nj nj nj nj
A. Propensity to go to the target receptor nj nj nj nj nj nj
B. Biological half-life nj
C. Pharmacodynamics
D. Safety and side effects nj nj nj
ANS: n j B PTS: n j 1
6. Azithromycin dosing requires the first day's dose be twice those of the other 4 days of
nj nj nj nj nj nj nj nj nj nj nj nj nj nj nj
theprescription. This is considered a loading dose. A loading dose:
nj nj nj nj nj nj nj nj nj nj nj
A. Rapidly achieves drug levels in the therapeutic range nj nj nj nj nj nj nj
B. Requires four to five half-lives to attain nj nj nj nj nj nj
C. Is influenced by renal function
nj nj nj nj
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()
nj
, lOMoAR cPSD| 21007614
D. Is directly related to the drug circulating to the target tissues
nj nj nj nj nj nj nj nj nj nj
ANS: n j A PTS: nj nj n j 1
7. The point in time on the drug concentration curve that indicates the first sign of a
nj nj nj nj nj nj nj nj nj nj nj nj nj nj nj
therapeuticeffect is the:
nj nj nj nj
A. Minimum adverse effect level nj nj nj
B. Peak of action nj nj
C. Onset of action nj nj
D. Therapeutic range nj
ANS: n j C PTS: n j 1
8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
nj nj nj nj nj nj nj nj nj nj nj nj
A. When the drug has a wide therapeutic range nj nj nj nj nj nj nj
B. When the drug will be administered for a short time only
nj nj nj nj nj nj nj nj nj nj
C. When there is a high correlation between the dose and saturation of receptor sites
nj nj nj nj nj nj nj nj nj nj nj nj nj
D. To determine if a drug is in the therapeutic range
nj nj nj nj nj nj nj nj nj
ANS: n j D PTS: n j 1
9. A laboratory result indicates the peak level for a drug is above the minimum
nj nj nj nj nj nj nj nj nj nj nj nj nj
toxicconcentration. This means that the:
nj nj nj nj nj nj
A. Concentration will produce therapeutic effects nj nj nj nj
B. Concentration will produce an adverse response nj nj nj nj nj
C. Time between doses must be shortened nj nj nj nj nj
D. Duration of action of the drug is too long nj nj nj nj nj nj nj nj
ANS: n j B PTS: n j 1
10. Drugs that are receptor agonists may demonstrate what property?
nj nj nj nj nj nj nj nj
A. Irreversible binding to the drug receptor site nj nj nj nj nj nj
B. Up-regulation with chronic use nj nj nj
C. Desensitization or down-regulation with continuous use nj nj nj nj nj
D. Inverse relationship between drug concentration and drug action
nj nj nj nj nj nj nj
ANS: n j C PTS: n j 1
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
nj nj nj nj nj nj nj nj nj nj
A. Down-regulation of the drug receptor nj nj nj nj
B. An exaggerated response if abruptly discontinued
nj nj nj nj nj
C. Partial blockade of the effects of agonist drugs nj nj nj nj nj nj nj
D. An exaggerated response to competitive drug agonists
nj nj nj nj nj nj
ANS: n j B PTS: n j 1
12. Factors that affect gastric drug absorption include:
nj nj nj nj nj nj
A. Liver enzyme activity nj nj
B. Protein-binding properties of the drug molecule nj nj nj nj nj
C. Lipid solubility of the drug nj nj nj nj
D. Ability to chew and swallow nj nj nj nj
ANS: n j C PTS: n j 1
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()
nj
