According to the dopamine hypothesis of schizoprhenia, dopamine levels in
schizophrenics are too: - ANSWER-High
After a year of chronic drinking, John has developed higher levels of enzymes involved
in alcohol metabolism in his stomach. This causes less of the drug to reach his
bloodstream after administration and is an example of: - ANSWER-pharmacokinetic
tolerance
Amphetamine primarily increases the intracellular concentration of dopamine by: -
ANSWER-Inhibiting VMAT-2
Anhedonia generally refers to: - ANSWER-Difficulty experiencing pleasure from things
in life other than drugs
Anhedonia is a term used to describe: - ANSWER-an inability to experience pleasure
Based on our discussion of hypofrontality, you would expect that a methamphetamine
addict: - ANSWER-would have a lower level of activity in her frontal lobes
Cocaine achieves its psychological effects primarily by: - ANSWER-blocking the
reuptake of dopamine, norepinephrine, and serotonin
Cocaine's mechanism involves blocking the _________ of dopamine, norepinephrine,
and serotonin. - ANSWER-reuptake
In a chronic alcohol drinker, levels of stomach enzymes that metabolize alcohol begin to
increase, causing more alcohol to be metabolized before it reaches the bloodstream.
What kind of tolerance is this and how will it affect the amount of alcohol they need to
drink to produce the effects they desire? - ANSWER-Pharmacokinetic, they will have to
drink more alcohol to produce the effect they desire
In addition to serotonin, duloxetine inhibits the reuptake of what other neurotransmitter?
- ANSWER-norepinephrine
Most antipsychotic drugs share this mechanism as part of their pharmacodynamics: -
ANSWER-Antagonism of dopamine receptors
Naltrexone acts as a/an: - ANSWER-opioid antagonist
Out of cocaine, amphetamine, and methamphetamine, which drug has the shortest half-
life? - ANSWER-cocaine
Patients who take this type of drug must be vigilant about their diet to make sure they
don't consume foods high in tyramine: - ANSWER-MAO-I