HIGH YIELD DRUGS FOR USMLE AND
COMLEX QUESTIONS AND ANSWERS
WITH SOLUTIONS 2024
Hypertension in pregnancy - ANSWER Hydralazine, methyldopa, labetalol, nifedipine
Patient has heparin induced thrombocytopenia - ANSWER STOP the heparin and give a direct thrombin
inhibitor (agatroban)
Patient needs NSAID but has gastric ulcers - ANSWER celecoxib (COX-2 inhibitor)
patient needs furosemide but has a sulfa allergy - ANSWER ethacrynic acid
gynecomastia - ANSWER spironolactone & ketaconazole
switch to eplerenone
diuretics - ANSWER HYPERcalcemia - caused by thiazides
HYPOcalcemia - caused by loops (loops lose)
Thiazide diuretics - ANSWER woresen gout and cause hyperuricemia
loop diuretics - ANSWER causes ototoxicity
Ototoxicity - ANSWER caused by aminoglycosides, loop diuretics, cisplatin, ASA (aspirin)
Nephrotoxicity - ANSWER caused by aminoglycosides and amophotercin B
Dilated cardiomyopathy - ANSWER caused by alcohol, doxorubin / danorubicin (aka chemotherapy)
COMLEX QUESTIONS AND ANSWERS
WITH SOLUTIONS 2024
Hypertension in pregnancy - ANSWER Hydralazine, methyldopa, labetalol, nifedipine
Patient has heparin induced thrombocytopenia - ANSWER STOP the heparin and give a direct thrombin
inhibitor (agatroban)
Patient needs NSAID but has gastric ulcers - ANSWER celecoxib (COX-2 inhibitor)
patient needs furosemide but has a sulfa allergy - ANSWER ethacrynic acid
gynecomastia - ANSWER spironolactone & ketaconazole
switch to eplerenone
diuretics - ANSWER HYPERcalcemia - caused by thiazides
HYPOcalcemia - caused by loops (loops lose)
Thiazide diuretics - ANSWER woresen gout and cause hyperuricemia
loop diuretics - ANSWER causes ototoxicity
Ototoxicity - ANSWER caused by aminoglycosides, loop diuretics, cisplatin, ASA (aspirin)
Nephrotoxicity - ANSWER caused by aminoglycosides and amophotercin B
Dilated cardiomyopathy - ANSWER caused by alcohol, doxorubin / danorubicin (aka chemotherapy)
