Human Development Lecture 3 – Female reproduction system
Female reproductive system;
• Produces sex hormone and functional gametes
• Protects and supports developing embryo
• Nourished (voeden) newborn infant
Organs of the female reproductive system;
• Ovaries (eierstokken)
• Uterine tubues (eileiders)
• Uterus (baarmoeder)
• Vagina
• Accessory glands; urethral glands,
greater vestibular gland
• External genitalia; clitoris, labia major
and labia minora
Ovaries, uterine tubes and uterus are enclosed by broad
ligament.
Functions ovaries;
• Production of immature female gametes (oocytes)
• Secretion of female sex hormones; estrogen and
progestins
o Feedback control uttering cycle
• Secretion inhibin
o Feedback control pituitary FSH
Oocytes are produced in the cortex of ovary and follicle (a group of cells)
Oogenesis (ovum production); Begins before birth, accelerate at puberty (menarch),
ends at menopause.
Gonad formation; primordial germ cells migrate to genital ridge in the developing
embryo.
Oogenesis (ovum production);
Primordial germ cell migrates to genital ridge in developing embryo
(4-6 weeks)
Develop into oogonia by mitosis (6 weeks-3 months)
All mitotic divisions are completed before birth.
Primary oocyte arises (3 months). 7 million are formed.
Prophase-resting primary oocyte may last very long.
Remaining primary oocyte begin meiosis I, proceed as far as
prophase I. Remain in that state until puberty begins. (diplotene
stage)
Puberty begins? Primordial follicle undergo maturation
Finished prophase I, producing secondary oocyte.
Polar bodies are formed also. (asymmetric cytokinesis)
Female reproductive system;
• Produces sex hormone and functional gametes
• Protects and supports developing embryo
• Nourished (voeden) newborn infant
Organs of the female reproductive system;
• Ovaries (eierstokken)
• Uterine tubues (eileiders)
• Uterus (baarmoeder)
• Vagina
• Accessory glands; urethral glands,
greater vestibular gland
• External genitalia; clitoris, labia major
and labia minora
Ovaries, uterine tubes and uterus are enclosed by broad
ligament.
Functions ovaries;
• Production of immature female gametes (oocytes)
• Secretion of female sex hormones; estrogen and
progestins
o Feedback control uttering cycle
• Secretion inhibin
o Feedback control pituitary FSH
Oocytes are produced in the cortex of ovary and follicle (a group of cells)
Oogenesis (ovum production); Begins before birth, accelerate at puberty (menarch),
ends at menopause.
Gonad formation; primordial germ cells migrate to genital ridge in the developing
embryo.
Oogenesis (ovum production);
Primordial germ cell migrates to genital ridge in developing embryo
(4-6 weeks)
Develop into oogonia by mitosis (6 weeks-3 months)
All mitotic divisions are completed before birth.
Primary oocyte arises (3 months). 7 million are formed.
Prophase-resting primary oocyte may last very long.
Remaining primary oocyte begin meiosis I, proceed as far as
prophase I. Remain in that state until puberty begins. (diplotene
stage)
Puberty begins? Primordial follicle undergo maturation
Finished prophase I, producing secondary oocyte.
Polar bodies are formed also. (asymmetric cytokinesis)
