Oxford Cambridge and RSA
Examinations Foundation
GCSECombined Science B Twenty First
Century ScienceJ260/04: Combined
science (Foundation Tier) General
Certificate of Secondary Education( with
marking scheme)
, Oxford Cambridge and RSA
Friday 9 June 2023 – Afternoon
GCSE (9–1) Combined Science B
(Twenty First Century Science)
J260/04 Combined Science (Foundation Tier)
Time allowed: 1 hour 45 minutes
F
* 9 9 3 0 6 8 6 3 4 9 *
You must have:
• a ruler (cm/mm)
• the Data and Equation Sheet for GCSE (9-1)
Combined Science B (inside this document)
You can use:
• an HB pencil
• a scientific or graphical calculator
* J 2 6 0 0 4 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 75.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 24 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2023 [601/8690/2] OCR is an exempt Charity
DC (PQ/SG) 329610/4 Turn over
, 2
1 Pathogens can cause diseases in humans.
Draw lines to connect each defence mechanism with the explanation of how it functions.
Defence mechanism Explanation
Clots the blood to prevent
Stomach acid
pathogens from entering cuts
Produces antibodies, or ingests
Skin
and digests pathogens
Barrier that prevents pathogens
Platelet
from entering the body
Can kill pathogens and stop
White blood cell
them from reproducing
[3]
© OCR 2023
, 3
2 (a) The plant genome is inside the nucleus of each cell.
(i) What is a genome?
...........................................................................................................................................
...................................................................................................................................... [1]
(ii) What is the function of the nucleus in a plant cell?
Tick (✓) one box.
It controls what goes into and out of the cell.
It controls how organisms develop and function.
It maintains the shape of the cell.
[1]
(b) Plants make small organic molecules including sugars, fatty acids, glycerol and amino acids.
Why is it important for plants to be able to make their own amino acids?
...................................................................................................................................................
.............................................................................................................................................. [1]
(c) Scientists can genetically engineer crop plants.
Complete the description of genetic engineering.
Use words from the list.
copied DNA modified protein removed desirable
Genetic engineering is a process in which the genome is ................................. so the crop
plant has ................................. characteristics.
[2]
© OCR 2023 Turn over
Examinations Foundation
GCSECombined Science B Twenty First
Century ScienceJ260/04: Combined
science (Foundation Tier) General
Certificate of Secondary Education( with
marking scheme)
, Oxford Cambridge and RSA
Friday 9 June 2023 – Afternoon
GCSE (9–1) Combined Science B
(Twenty First Century Science)
J260/04 Combined Science (Foundation Tier)
Time allowed: 1 hour 45 minutes
F
* 9 9 3 0 6 8 6 3 4 9 *
You must have:
• a ruler (cm/mm)
• the Data and Equation Sheet for GCSE (9-1)
Combined Science B (inside this document)
You can use:
• an HB pencil
• a scientific or graphical calculator
* J 2 6 0 0 4 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 75.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 24 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2023 [601/8690/2] OCR is an exempt Charity
DC (PQ/SG) 329610/4 Turn over
, 2
1 Pathogens can cause diseases in humans.
Draw lines to connect each defence mechanism with the explanation of how it functions.
Defence mechanism Explanation
Clots the blood to prevent
Stomach acid
pathogens from entering cuts
Produces antibodies, or ingests
Skin
and digests pathogens
Barrier that prevents pathogens
Platelet
from entering the body
Can kill pathogens and stop
White blood cell
them from reproducing
[3]
© OCR 2023
, 3
2 (a) The plant genome is inside the nucleus of each cell.
(i) What is a genome?
...........................................................................................................................................
...................................................................................................................................... [1]
(ii) What is the function of the nucleus in a plant cell?
Tick (✓) one box.
It controls what goes into and out of the cell.
It controls how organisms develop and function.
It maintains the shape of the cell.
[1]
(b) Plants make small organic molecules including sugars, fatty acids, glycerol and amino acids.
Why is it important for plants to be able to make their own amino acids?
...................................................................................................................................................
.............................................................................................................................................. [1]
(c) Scientists can genetically engineer crop plants.
Complete the description of genetic engineering.
Use words from the list.
copied DNA modified protein removed desirable
Genetic engineering is a process in which the genome is ................................. so the crop
plant has ................................. characteristics.
[2]
© OCR 2023 Turn over
