Pharmacokinetics Summary via powerpoint
Lecture 1:
→ for first pass loss
, → relationship - dose effect
→ takes time to get effect after drug use
→ every patient has some variability
, → factors of variability
→ patients don’t use drug as prescribed by doctor
ADME used to predict plasma time curve
Lecture 2:
, → intravenous bolus dose
→ Vd= dose/ C0
→first order-elimination
This formula eventually becomes→
- Where line declines is elimination rate constant
Lecture 1:
→ for first pass loss
, → relationship - dose effect
→ takes time to get effect after drug use
→ every patient has some variability
, → factors of variability
→ patients don’t use drug as prescribed by doctor
ADME used to predict plasma time curve
Lecture 2:
, → intravenous bolus dose
→ Vd= dose/ C0
→first order-elimination
This formula eventually becomes→
- Where line declines is elimination rate constant
