Chapter 6 practice questions metabolism and toxicology.

1. Which of the following statements regarding axons and/or axonal transport is
FALSE?
- A majority of the ATP in nerve cells is used for axonal transport.
2. Which of the following statements is not characteristic of Schwann cells in
Wallerian degeneration?
- Schwann cells increase synthesis of myelin lipids in response to axonal
damage.
3. Prenatal exposure to ethanol can result in mental retardation and hearing
deficits in the newborn. What is the cellular basis of the neurotoxicity?
- microcephaly.
4. Which of the following characteristics is LEAST likely to place a neuron at risk
of toxic damage?
- ability to release neurotransmitters.
5. The use of meperidine contaminated with MPTP will result in a Parkinson’s
disease-like neurotoxicity. Where is the most likely site in the brain that MPTP
exerts its toxic effects?
- substantia nigra.
6. Which of the following statements regarding the PNS and the CNS is TRUE?
- PNS axons can regenerate, whereas CNS axons cannot.
7. Platinum (cisplatin) results in which of the following neurologic problems?
- peripheral neuropathy.
8. Which of the following is NOT characteristic of axonopathies?
- A majority of axonal toxicants cause motor deficits.
9. All of the following statements regarding lead exposure are true EXCEPT:
- Lead causes the transection of peripheral axons.
10. Regarding excitatory amino acids, which of the following statements is
FALSE?
- An ionotropic glutamate receptor is coupled to a G protein.