WGU D116 UNIT 2 QUESTIONS & ANSWERS
Pharmacokinetics (4) - Answers -study of drug movement throughout the body
. absorption
. distribution
. metabolism
. excretion
Pharmacodynamics (4) - Answers -what the drug does to the body
. dose-response relationships
. drug-receptor interactions
. drug responses that do not involve receptors
. the therapeutic index
Drug interactions - Answers -The effects that may occur when the drug is given along
with another drug, food, or substance
Absorption - Answers -the drugs movement from its site of admin to the blood
Distribution - Answers -drugs movement from the blood to the interstitial space of
tissues and from there into cells
Metabolism (biotransformation) - Answers -the process by which the body chemically
changes drugs into a form that can be excreted
. most drug metabolism takes place in the liver
Excretion - Answers -the movement of drugs and their metabolites out of the body
- kidneys (major organs of drug excretion)
elimination - Answers -combination of metabolism and excretion
what determines the concentration of a drug at its sites of action? - Answers -the four
pharmacokinetic processes
ways to cross a cell membrane (3) - Answers -. passage through channels or pores
. passage with the aid of a transport system
. direct penetration of the membrane itself (most common)
channels and pores - Answers -very few drugs cross this way, only smallest
compounds
ex: K+ and Na+ (only if the channel is the right one)
transport system - Answers -carriers that can move drugs from one side of the cell
membrane to the other side
Pharmacokinetics (4) - Answers -study of drug movement throughout the body
. absorption
. distribution
. metabolism
. excretion
Pharmacodynamics (4) - Answers -what the drug does to the body
. dose-response relationships
. drug-receptor interactions
. drug responses that do not involve receptors
. the therapeutic index
Drug interactions - Answers -The effects that may occur when the drug is given along
with another drug, food, or substance
Absorption - Answers -the drugs movement from its site of admin to the blood
Distribution - Answers -drugs movement from the blood to the interstitial space of
tissues and from there into cells
Metabolism (biotransformation) - Answers -the process by which the body chemically
changes drugs into a form that can be excreted
. most drug metabolism takes place in the liver
Excretion - Answers -the movement of drugs and their metabolites out of the body
- kidneys (major organs of drug excretion)
elimination - Answers -combination of metabolism and excretion
what determines the concentration of a drug at its sites of action? - Answers -the four
pharmacokinetic processes
ways to cross a cell membrane (3) - Answers -. passage through channels or pores
. passage with the aid of a transport system
. direct penetration of the membrane itself (most common)
channels and pores - Answers -very few drugs cross this way, only smallest
compounds
ex: K+ and Na+ (only if the channel is the right one)
transport system - Answers -carriers that can move drugs from one side of the cell
membrane to the other side
