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immunohematology - CORRECT ANSWER-the study of the immune aspects of
hematology to provide safe therapeutic blood products to patients
accuracy in blood banking - CORRECT ANSWER-100% accurate to avoid severe
transfusion reactions due to incompatibility
Accuracy w/ recording - CORRECT ANSWER-Donated blood units need to be
typed properly to ensure they are given to the right patient
Accuracy w/ Interpreting - CORRECT ANSWER-typed properly to ensure they
receive the correct units of blood
antigen (Ag) - CORRECT ANSWER-a substance that is recognized by the body as
being foreign, which causes an immune response
,antibody (Ab) - CORRECT ANSWER-a protein substance that is secreted by
plasma cells in response to an antigen
hemolysis - CORRECT ANSWER-the disruption of the RBC membrane, causing
release of hemoglobin into the plasma
agglutination - CORRECT ANSWER-the clumping of RBCs (or other particulate)
due to interaction of antibodies with their corresponding antigen
blood test at donor collection facility - CORRECT ANSWER--ABO and Rh typing
-infectious disease testing: syphillis, hepatitis B & C, AIDS/HIV, HTLV I & II, west
nile virus, Chagas disease (T. cruzi)
-ABO and Rh types reconfirmed
blood test at transfusion center - CORRECT ANSWER--reconfirmation of ABO
type (make sure it matches the label)
-pre-transfusion testing on patient: ABO, Rh type, antibody screen, crossmatch
Food and Drug Administration (FDA) - CORRECT ANSWER-regulates all blood
component manufacturers, distributors and medical laboratories in the US
,-provides licensure and approves all methods and products used for blood
collection
-center for biological evaluation and research (CBER)
-control blood collection and manufacturing of pharmaceuticals
AABB - CORRECT ANSWER--Standards for blood collection centers and
transfusion centers
-voluntary accreditation of either people or facilities
-writes technical manuals
-ensures that standards for CMS (Medicare and Medicaid) are met
College of American pathologists (CAP) - CORRECT ANSWER--voluntary
accreditation of clinical laboratories
-administer proficiency testing for clinical laboratories
Past blood banking issues - CORRECT ANSWER-Multiple blood groups
Circulatory overload
Blood storage and expiration
, Multiple blood groups - CORRECT ANSWER-Even with knowing about ABO
there were still transfusion reactions going on that lead to discovery of other
blood groups
Circulatory overload - CORRECT ANSWER-People who only needed 1
component of blood were given whole blood that gave an overload of cells and
volume, leading to production of apheresed products
Blood storage and expiration - CORRECT ANSWER-Blood that was collected
would expire really quickly so research was need to figure out what would extend
the shelf life
RBC membrane - CORRECT ANSWER-Phospholipid bilayer
Semipermeable
Integral proteins
Peripheral proteins
Protein cytoskeleton
Spectrin
(RBC Membrane) Phospholipid Bilayer - CORRECT ANSWER-Containing
glycolipids and immunoproteins