FM EORE Infectious Disease Review | 80+ Questions with Answers | MED315 | Meningitis, Mono, Lyme, HIV, Diarrheal Illnesses

This expert-verified document provides over 80 clinically relevant multiple-choice questions and answers for the Infectious Disease section of the Family Medicine End of Rotation Exam (EORE), aligned with the 2025 academic year curriculum. Tailored for students in MED315 or those completing rotations in family medicine, internal medicine, or infectious disease, this guide is designed to reinforce high-yield topics in microbial diagnosis, transmission, symptomatology, and treatment. Key topics include: Mononucleosis (EBV): clinical signs (posterior cervical lymphadenopathy, splenomegaly, palatal petechiae), heterophile antibody testing, and ampicillin-induced rash Lyme Disease: stages (early, disseminated, late), characteristic target lesion, neurologic/cardiac complications, IgM/IgG serology, and doxycycline treatment Bacterial Meningitis: age-based empiric treatment (ceftriaxone, vancomycin, ampicillin), classic triad (fever, AMS, nuchal rigidity), Brudzinski and Kernig signs, steroid use, and post-exposure prophylaxis Viral vs. Fungal Meningitis: subacute/chronic presentations including Cryptococcus in immunocompromised patients Influenza: systemic symptoms, indications for antivirals (oseltamivir/zanamivir), supportive care timelines Neisseria meningitidis: outbreaks in young patients in communal living spaces, gram-negative diplococci, and rifampin prophylaxis Gastrointestinal Infections: Salmonella: bloody diarrhea, fever, and abdominal cramping; fluid replacement and antibiotics for severe cases Shigella: abrupt onset of tenesmus, bloody mucus stools, diagnosis via stool culture/sigmoidoscopy, TMP-SMX treatment HIV screening and confirmation: initial ELISA followed by Western blot confirmation This resource is particularly beneficial for: Physician Assistant (PA) students preparing for the Infectious Disease EORE Medical students (MD/DO) on family medicine or ID rotations Nurse Practitioner (NP) and Nursing (BSN, RN) students managing infectious conditions in outpatient/inpatient settings International medical graduates preparing for USMLE Step 2 CK or PANCE Structured for rapid recall and clinical scenario-based reasoning, this guide offers critical insight into infection-related emergencies and core primary care protocols. Keywords: infectious disease, EORE, mononucleosis, meningitis, Neisseria meningitidis, Lyme disease, influenza, HIV screening, ELISA, Western blot, bacterial meningitis, Brudzinski sign, Kernig sign, salmonella, shigella, diarrheal disease, doxycycline, oseltamivir, TMP-SMX, ceftriaxone, vancomycin, ampicillin