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T1DM - 🧠 ANSWER ✔✔- Destruction of beta cells (antibodies)
- Adolescents
- Fatigue, polydipsia, polyuria
- Requires insulin
- Basal long acting insulin (glargine or determir)
- Pre-meal rapid acting insulin (lisper or aspart)
- DKA (BS <1000, hypokalemic)
T2DM - 🧠 ANSWER ✔✔-- Insulin resistance related to obesity
- Fatigue, polydipsia, polyuria
, - Diet, exercise, wt loss
- Metformin, sulfonylurea
- Insulin if HbA1c >9%
- HHS (BS >1000, hypokalemic)
Diagnosing diabetes - 🧠 ANSWER ✔✔- 2 FBGs >126
- 1 glucose level >200 w/ symptoms
- HA1c >6.5%
- Positive 2 hr oral GTT
Adrenal insufficiency - 🧠 ANSWER ✔✔- 1°: Addison disease
- *Hypocortisiolism*
- Weakness, fatigue, anorexia, weight loss
- Hyperpigmentation (1° disease)
- *Hyponatremia and hyperkalemia* (1° disease)
- ↑ ACTH = 1° disease
- ↓ ACTH = 2° disease
- Hydrocortisone