NR546 NR 546 Psychopharmacology for the Psychiatric-Menta
Health Nurse Practitioner
1.Drug metabolism is influenced by client factors sterm-42uch as
Answer age, smok- ing, caffeine intake, or other medications.
2.Glutamate
Answer Most abundant, principle excitatory neurotransmitter in the
brain, constituting 60% of all neurotransmitters
3.Glutamate plays a major role in &
Answer leaning & memory in the CNS
4.Main on switch, excitatory
Answer Glutamate
5.Non-essential amino acid that does not cross the brain barrier
Answer Glu- tamate
6.Decussation happens in glutamate pathway 2. describe decussation
Answer cross- ing to the other side of the body. causing muscles to
contract. Due to decussation, a stroke on one side of the cortex will will
cause weakness on the opposite side of the body.
1/
12
, 7.The vental statium has glutamate input from the ,
,&
Answer prefrontal cortex, hippocampus, and the amygdala which
are all critical components of the reward circuitry
8.Too much glutamate causes
Answer Parkinsons disease, Alzheimers Disease, & Hunt- ingtons Disease
9.Cerebellum controls
Answer motor coordination
10.Name the 3 types of ionotropic glutamate receptors
Answer 1.alpha amino 3 hy- droxy 5 methyl 4 isoxazolepropionic
(AMPA)
2.Kainate
3.N-methyl-D-asparate (NMDA)
11.(AMPA) & Kainate are very simular and are considered as one
Answer true
12. When glutamate binds to the AMPA/Kainate receptor it opens a
Ligand-gat- ed ion channel Na+ & K+ are exchanged
Answer the exchange of the Na+ and K+ leads to the opening of
voltage gated Na+ channels, triggering an action potential.
2/
12
Health Nurse Practitioner
1.Drug metabolism is influenced by client factors sterm-42uch as
Answer age, smok- ing, caffeine intake, or other medications.
2.Glutamate
Answer Most abundant, principle excitatory neurotransmitter in the
brain, constituting 60% of all neurotransmitters
3.Glutamate plays a major role in &
Answer leaning & memory in the CNS
4.Main on switch, excitatory
Answer Glutamate
5.Non-essential amino acid that does not cross the brain barrier
Answer Glu- tamate
6.Decussation happens in glutamate pathway 2. describe decussation
Answer cross- ing to the other side of the body. causing muscles to
contract. Due to decussation, a stroke on one side of the cortex will will
cause weakness on the opposite side of the body.
1/
12
, 7.The vental statium has glutamate input from the ,
,&
Answer prefrontal cortex, hippocampus, and the amygdala which
are all critical components of the reward circuitry
8.Too much glutamate causes
Answer Parkinsons disease, Alzheimers Disease, & Hunt- ingtons Disease
9.Cerebellum controls
Answer motor coordination
10.Name the 3 types of ionotropic glutamate receptors
Answer 1.alpha amino 3 hy- droxy 5 methyl 4 isoxazolepropionic
(AMPA)
2.Kainate
3.N-methyl-D-asparate (NMDA)
11.(AMPA) & Kainate are very simular and are considered as one
Answer true
12. When glutamate binds to the AMPA/Kainate receptor it opens a
Ligand-gat- ed ion channel Na+ & K+ are exchanged
Answer the exchange of the Na+ and K+ leads to the opening of
voltage gated Na+ channels, triggering an action potential.
2/
12
