NR566 / NR 566 Final Exam Study Guide Advanced
Pharmacology for Care of the Family Expected Questions and
Verified Answers
1. What are the two main hormones responsible for female
maturation and regulation of female reproductive organ
activity?
Ans>> Estrogen and progestogens
2. What is the principle Endogenous estrogen
Ans>> estradiol
3. What is the principal Endogenous pro gestational hormone?
Ans>> Progesterone
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,4. Name the two menstrual cycle phases
Ans>> Follicular phase(1-14) Luteal phase (15-28)
5. During the follicular phase of the menstrual cycle estrogen's are
synthe- sized by what
Ans>> Ovarian follicles
6. During the luteal phase estrogens are synthesized by
Ans>> Corpus luteum
7. True or False Estrogen acts through receptors in the cell
Ans>> True
8. Estrogen receptor alpha is highly expressed where
Ans>> In the vagina uterus ovaries mammary glands vascular
epithelium and hypothalamus
9. Estrogen receptor beta is expressed where
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11
,Ans>> Ovary and prostate Les extent in the lungs brain bones and blood
vessels
10.How does estrogen affect bone loss
Ans>> Without estrogen bone resorption Ac- celerates leading to loss of bone
density shortly after menopause
11.Adverse effects of estrogen therapy
Ans>> Endometrial hyperplasia endometrial cancer breast cancer cardiovascular
thromboembolic events
12.Use of estrogen during menopause can
Ans>> Produce or uncover gallbladder dis- ease cause jaundice in women with
pre-existing liver dysfunction nausea headache
13.Contraindications of using estrogens
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11
,Ans>> Patients with a history of DVTPE stroke myocardial infarction secondary to a
thromboembolic event women who are preg- nant or have vagina bleeding without
a known cause history of liver disease estrogen dependent tumors or breast
cancer
14.When can progesterone be used
Ans>> To reduce chances of endometrial hyperpla- sia and endometrial cancer
when using estrogen
15.How would inducers or inhibitors interact with estrogens
Ans>> Inducers lower estrogen
levels Inhibitors raise estrogen
levels
16.Patient teaching for transdermal patch
Ans>> 1 Apply to an area of clean dry and intact skin on the abdomen or some
other region of the trunk but not the breast or waist line by pressing the patch
firmly in place for 10 seconds
4/
11
Pharmacology for Care of the Family Expected Questions and
Verified Answers
1. What are the two main hormones responsible for female
maturation and regulation of female reproductive organ
activity?
Ans>> Estrogen and progestogens
2. What is the principle Endogenous estrogen
Ans>> estradiol
3. What is the principal Endogenous pro gestational hormone?
Ans>> Progesterone
1/
11
,4. Name the two menstrual cycle phases
Ans>> Follicular phase(1-14) Luteal phase (15-28)
5. During the follicular phase of the menstrual cycle estrogen's are
synthe- sized by what
Ans>> Ovarian follicles
6. During the luteal phase estrogens are synthesized by
Ans>> Corpus luteum
7. True or False Estrogen acts through receptors in the cell
Ans>> True
8. Estrogen receptor alpha is highly expressed where
Ans>> In the vagina uterus ovaries mammary glands vascular
epithelium and hypothalamus
9. Estrogen receptor beta is expressed where
2/
11
,Ans>> Ovary and prostate Les extent in the lungs brain bones and blood
vessels
10.How does estrogen affect bone loss
Ans>> Without estrogen bone resorption Ac- celerates leading to loss of bone
density shortly after menopause
11.Adverse effects of estrogen therapy
Ans>> Endometrial hyperplasia endometrial cancer breast cancer cardiovascular
thromboembolic events
12.Use of estrogen during menopause can
Ans>> Produce or uncover gallbladder dis- ease cause jaundice in women with
pre-existing liver dysfunction nausea headache
13.Contraindications of using estrogens
3/
11
,Ans>> Patients with a history of DVTPE stroke myocardial infarction secondary to a
thromboembolic event women who are preg- nant or have vagina bleeding without
a known cause history of liver disease estrogen dependent tumors or breast
cancer
14.When can progesterone be used
Ans>> To reduce chances of endometrial hyperpla- sia and endometrial cancer
when using estrogen
15.How would inducers or inhibitors interact with estrogens
Ans>> Inducers lower estrogen
levels Inhibitors raise estrogen
levels
16.Patient teaching for transdermal patch
Ans>> 1 Apply to an area of clean dry and intact skin on the abdomen or some
other region of the trunk but not the breast or waist line by pressing the patch
firmly in place for 10 seconds
4/
11
