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Where are H4 receptors located? -nursing predominantly found on eosinophils,
neutrophils, and T cells.
In the stomach, histamine is released by: -nursing enterochromaffin-like (ECL) cells
Toxic effect of first-generation antihistamines -nursing cardiac arrhythmias
Anaphylaxis and Antihistamine -nursing Steroids may be added as adjunct therapy
Central nervous system side effect of antihistamines that elderly patients should be
aware of -nursing fatigue
Indication of H2 antihistamines used -nursing used to inhibit the secretion of gastric acid
in patients with gastrointestinal (GI) disorders
Which of the following is a second-generation antihistamine that cannot be removed by
hemodialysis? -nursing Cetirizine (Zyrtec)
Initial selection of antimicrobial therapy is: -nursing Initial selection of antimicrobial
therapy is typically empiric, meaning before the causative pathogen has been identified
Food-drug or drug-drug interactions with antibacterial medications are usually
addressed by: -nursing This interaction is usually addressed by separating the
administration times or avoiding the combination
Multiple drug combination treatment for tuberculosis -nursing It has decreased risk of
resistance
Know about description of IFN-B -nursing FN-β products have antiviral properties but
are used for multiple sclerosis, not infections
Side effect of first-generation antihistamines related to their anticholinergic activity? -
nursing dry mouth, dry eyes, urinary retention, constipation, and cognitive disturbances.
Anticholinergic side effects can be further exacerbated by other anticholinergic
medications, such as tricyclic antidepressants (TCAs). Because monoamine oxidase
inhibitors (MAOIs) can also exacerbate anticholinergic side effects, first-generation
, antihistamines should not be used during treatment or within 2 weeks of MAOI
discontinuation
How is enterobiasis diagnosed? -nursing Pinworm can be diagnosed by perianal swab
using adhesive tape that is examined microscopically for eggs
Know tuberculosis treatment. -nursing Directly observed therapy (DOT) is a strategy to
ensure adherence to the drug regimen and is an especially critical element to regimens
with any frequency less than daily dosing.
Because these agents are highly susceptible to drug-drug interactions, any exaggerated
side effects or inadequate therapeutic responses when using isoniazid and rifamin
should be considered in light of potential drug interactions with other medications the
patient is taking concurrently.
According to the universal prescribing alerts for aminoglycosides, extended use
increases risk for infection by which of the following pathogens? -nursing Can cause C.
difficile-associated diarrhea and pseudomembranous colitis with extended use
Systemic chemotherapy that is given prior to surgery or radiation serves to: -nursing
The use of systemic treatment to eliminate micrometastatic disease after surgery or
radiation is called adjuvant therapy. When it is administered, the goal is to prevent
recurrence of the cancer and improve survival. Systemic therapy can also be given prior
to surgery or radiation; in this case, it is called neoadjuvant therapy. The purpose of
neoadjuvant therapy is to reduce the tumor burden and to increase the effectiveness of
the local treatment.
How is tumor lysis syndrome managed in leukemia patients? -nursing IV hydration
Acrolein is a toxic metabolite of cyclophosphamide and ifosfamide that can cause: -
nursing hemorrhagic cystitis
Which category of antineoplastic drugs offers an alternative when traditional treatments
fail? -nursing Immunosupressant antineoplastic agents
Topoisomerase inhibitors target enzymes that control changes in DNA -nursing
structure
Which method is used to administer dactinomycin? -nursing only by the intravenous
route
FDA-approved indication for methotrexate? -nursing Meningeal leukemia
Trophoblastic neoplasms
Breast cancer
Folate antimetabolites are eliminated primarily through the: -nursing kidneys