NR 566 ADVANCED PHARMACOLOGY FOR THE
CARE OF THE FAMILY- WEEK 1 ANTIFUNGAL
AGENTS EXAM QUESTIONS & ANSWERS
PASSED ALREADY GRADED A+
1. Amphotericin B is a
polyene
antibiotic is it well absorbed in no; poorly absorbed.
the GI tract? PO therapy won't
work. must be given
IV!
undergoes binding
to sterol-containing
mem- branes of
tissues
2. Amphotericin B must be given IV
3. Amphotericin B should be used in
life threatening infections
impairment occurs in all pts Renal
4. when it comes to _, kidney damage = total amphotericin B
dose in tx
5. if Amphotericin B dose > _ g, permanent highly
damage is likely to occur, can be decreased
by infusing 1 L of saline nephrotoxic 4
6. if plasma creatinine is > , decrease dose 3.5
7. high levels of Itraconazole can cause fatal if taking
and
1/
21
,NR 566 ADVANCED PHARMACOLOGY FOR THE
CARE OF THE FAMILY- WEEK 1 ANTIFUNGAL
AGENTS EXAM QUESTIONS & ANSWERS
PASSED ALREADY GRADED A+
: monitor levels!
ventricular dysrhythmias
8. if taking Itraconazole with : PT time
should be monitored! can be by azoles digoxin,
if taking Itraconazole with : check
blood cyclosporine
warfarin; increased
sulfonylureas;
increased
2/
21
, NR 566 ADVANCED PHARMACOLOGY FOR THE
CARE OF THE FAMILY- WEEK 1 ANTIFUNGAL
AGENTS EXAM QUESTIONS & ANSWERS
PASSED ALREADY GRADED A+
sugar can be by azoles, causing severe
hy- poglocemia
9. itraconazole is a spectrum broad
antifungal
Azoles are often used as alternatives to
_ for most systemic fungal infections, Amphotericin B
systemic and superficial mycoses
10. old people have higher risk for , decreasing achlorhydria (no
gastric
ability to absorb antifungal meds. -peritonitis
- pleural
11. Do not take Itraconazole with meds that raise space
gastric pH: , , - intraabdom
inal
abscesses
12. Caspofungin is a
often used in form
13. Caspofungin can be used to treat:
-invasive aspergillosis (fungal lung infection)
-systemic infections
-Candidemia
-Candida-related
3/
21
CARE OF THE FAMILY- WEEK 1 ANTIFUNGAL
AGENTS EXAM QUESTIONS & ANSWERS
PASSED ALREADY GRADED A+
1. Amphotericin B is a
polyene
antibiotic is it well absorbed in no; poorly absorbed.
the GI tract? PO therapy won't
work. must be given
IV!
undergoes binding
to sterol-containing
mem- branes of
tissues
2. Amphotericin B must be given IV
3. Amphotericin B should be used in
life threatening infections
impairment occurs in all pts Renal
4. when it comes to _, kidney damage = total amphotericin B
dose in tx
5. if Amphotericin B dose > _ g, permanent highly
damage is likely to occur, can be decreased
by infusing 1 L of saline nephrotoxic 4
6. if plasma creatinine is > , decrease dose 3.5
7. high levels of Itraconazole can cause fatal if taking
and
1/
21
,NR 566 ADVANCED PHARMACOLOGY FOR THE
CARE OF THE FAMILY- WEEK 1 ANTIFUNGAL
AGENTS EXAM QUESTIONS & ANSWERS
PASSED ALREADY GRADED A+
: monitor levels!
ventricular dysrhythmias
8. if taking Itraconazole with : PT time
should be monitored! can be by azoles digoxin,
if taking Itraconazole with : check
blood cyclosporine
warfarin; increased
sulfonylureas;
increased
2/
21
, NR 566 ADVANCED PHARMACOLOGY FOR THE
CARE OF THE FAMILY- WEEK 1 ANTIFUNGAL
AGENTS EXAM QUESTIONS & ANSWERS
PASSED ALREADY GRADED A+
sugar can be by azoles, causing severe
hy- poglocemia
9. itraconazole is a spectrum broad
antifungal
Azoles are often used as alternatives to
_ for most systemic fungal infections, Amphotericin B
systemic and superficial mycoses
10. old people have higher risk for , decreasing achlorhydria (no
gastric
ability to absorb antifungal meds. -peritonitis
- pleural
11. Do not take Itraconazole with meds that raise space
gastric pH: , , - intraabdom
inal
abscesses
12. Caspofungin is a
often used in form
13. Caspofungin can be used to treat:
-invasive aspergillosis (fungal lung infection)
-systemic infections
-Candidemia
-Candida-related
3/
21
