IMMUNOLOGY EXAM 5 WEIGEL| Questions and Answers 100% Verified| Newest !

IMMUNOLOGY EXAM 5 WEIGEL| Questions and Answers 100% Verified| Newest ! What different cells can become plasma cells. activated B cells ; isotype switched, somatically hypermutated centrocytes ; memory B cells What are the components of the B cell co-receptor CR2 ; CD19 ; CD81 = TAPA-1 What does CR1 do for the co-receptor? Helps ________ to cleave __________ ; Binding of _____ (On the B-cell) to ______ (on the pathogen) makes it susceptible to cleavage to ______. _______ (part of the B-cell co-receptor) can then bind to the ______. The signal is sent through ________. factor I ; C3b>C3d ; CR1 ; C4b ; C4d ; CR2 ; C3d ; CD19 CR1 binds to ________ C4B TI stands for _____________ ; TD stands for _______________ Thymus independent ; Thymus dependent Describe B cell activation, CD40 ligand, CD40, NFkB, ICAM-1 and IL-4 secretion by T cells. For B cell activation the ______ must meet its appropriate antigen, and the co- receptor, CD40 must meet _________ on a T cell. The CD40:CD40L interaction causes the B cell to activate transcription factor _______, NFkB regulates ___________ and once NFkB is activated ________ is up regulated and expressed on the B cell surface. ICAM-1 on the B cell surface then binds to ________ on the T cell surface. Once these receptors have been connected the T cell begins to secrete _______ onto the B cell surface. IL-4 is very important cytokine that drives __________________. BCR ; CD40L ; NFkB ; ICAM-1 ; ICAM-1 ; LFA-1 ; IL-4 ; B cell proliferation Define: follicular dendritic cells (dark zone/light zone) Characteristic ________________ cells of follicles in ________________ lymphoid tissues. They have _________ branching processes that make intimate contact with _____________ and have