NBME CBSE Real Exam 200 Questions with 100% Correct Answers Latest 2025–2026 Active Forms (25–31) | Scored A+ / 260–280+ Predictor Real Retired + High-Yield Predictive Questions | Updated November 2025

The NBME CBSE Real Exam 200 Questions with 100% Correct Answers 2025–2026 is the single most powerful, underground resource for any medical student who needs to crush the NBME Comprehensive Basic Science Examination (CBSE), CCSE, or predict a 260–280+ on USMLE Step 1. This is NOT a recall or approximation. These are 200 real, retired questions pulled directly from the active 2025–2026 NBME pool (Forms 25, 26, 27, 28, 29, 30, and 31) that are currently being administered at every U.S. MD and DO school. Every question has been verified by at least three students who sat for the exact form within the last 90 days. Every answer is 100% correct with detailed, step-by-step explanations that include First Aid 2025 page references, UWorld ID numbers, Pathoma chapter, and Sketchy/Pixorize topic. Students who master these exact 200 questions routinely score in the 90th–99th percentile on their actual CBSE and predict 260–280+ on Step 1. Why These Exact 200 Questions Are All You Need The NBME reuses high-yield stems and concepts across all current forms. These 200 questions represent the highest-yield, most frequently repeated vignettes and images from Forms 25–31 — the only forms in active rotation as of November 2025. Key advantages: 100% real retired questions — no fakes, no recalls, no approximations 100% correct answers with full explanations (average 180–250 words each) Exact form and block number tagged on every question Includes the hardest, most-discussed images (electron micrographs, histology, gross pathology, biostats graphs) Anki-ready .apkg deck included (pre-made cloze + image occlusion cards) Discipline Breakdown (mirrors current NBME weighting) Pathology & Pathophysiology – 38% (76 questions) Physiology – 16% (32 questions) Pharmacology – 14% (28 questions) Microbiology & Immunology – 12% (24 questions) Biochemistry & Genetics – 10% (20 questions) Biostatistics & Ethics – 6% (12 questions) Anatomy & Embryology – 4% (8 questions) Sample Real 2025–2026 Questions (Direct from Active Forms) (Form 30, Block 3) 58-year-old man with fatigue, splenomegaly, and tear-drop cells on peripheral smear → Diagnosis? Answer: Primary myelofibrosis (JAK2 V617F positive) (Form 31, Block 2) Arrow pointing to area of pancreas with loss of islets and lymphocytic infiltrate → Diagnosis? Answer: Type 1 diabetes mellitus (autoimmune destruction) (Form 29, Block 4) Child with recurrent sinopulmonary infections, absent tonsils, low IgG, normal T cells → Most likely genetic defect? Answer: X-linked agammaglobulinemia (BTK mutation) (Form 30, Block 1) 45-year-old woman with weight gain, easy bruising, purple striae → Lab shows elevated late-night salivary cortisol → Next best test? Answer: 1-mg overnight dexamethasone suppression test (Form 31, Block 4) Biostats: New screening test has sensitivity 95%, specificity 90%. Prevalence 1 in 1,000. Positive predictive value ≈ ? Answer: ~9.5% (full calculation provided) (Form 28, Block 2) Classic electron micrograph of kidney with subepithelial humps → Diagnosis? Answer: Post-streptococcal glomerulonephritis 2025–2026 Content Updates Already Included New monoclonal antibodies (teplizumab, lecanemab, RSV mAbs) Updated immunology (CAR-T, bispecific antibodies) New microbiology (C. auris, mpox, XDR-TB) Updated ethics (AI in diagnosis, gene editing, physician burnout) New biostats (diagnostic accuracy, N-of-1 trials, Bayesian reasoning) Student-Friendly Features Clean, bookmarked PDF with clickable index by form/block Every explanation includes First Aid 2025 page, UWorld QID, and Sketchy topic “Appeared on 4+ Forms” tag on 47 ultra-high-yield repeats Full-color images for every histology, pathology, and EM question Anki deck pre-tagged with #NBME-Real-200 and subtopic Score conversion chart (your % correct → predicted Step 1 score) Real Documented 2025–2026 Results “Scored 272 on Step 1. Had 61 of these exact 200 on my CBSE and 28 on test day.” – J.L., Class of 2026 “Form 31 was 73 questions identical or one word different. Predicted 268 → actual 274.” – S.R., DO student “My school uses these forms for shelf exams too. This PDF carried my entire preclinical.” – M.P., Caribbean IMG Ideal For U.S. MD/DO students taking CBSE, CCSE, or school-specific NBME exams Students required to hit a minimum CBSE score for Step 1 eligibility IMGs and repeat test-takers aiming for 250+ Anyone supplementing UWorld, First Aid, Pathoma, Sketchy, Anki The NBME completely retired Forms 18–24 in 2024 and introduced a new writing committee for Forms 25–31. Every other “200 NBME questions” PDF online is obsolete and will hurt your score. This is the only file with the real, current 200 questions you will actually see in 2025–2026. Download today and lock in your A+ / 260–280+ before your next CBSE.