Family Nurse Practitioner Certification
Exam Practice Test Questions And
Correct Answers (Verified Answers) Plus
Rationales 2026 Q&A | Instant
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1. A 32-year-old female presents with dysuria, frequency, and urgency.
Which organism is most commonly responsible for uncomplicated urinary
tract infections?
A. Staphylococcus aureus
B. Escherichia coli
C. Pseudomonas aeruginosa
D. Enterococcus faecalis
Rationale: Escherichia coli is the most frequent cause of uncomplicated
urinary tract infections due to its uropathogenic virulence factors that
allow adherence to uroepithelial cells._
,2. A 45-year-old male with hypertension presents for a follow-up. Which
antihypertensive drug is preferred as first-line therapy in the absence of
comorbidities?
A. Beta-blocker
B. Alpha-blocker
C. Thiazide diuretic
D. Loop diuretic
Rationale: Thiazide diuretics are recommended as first-line
antihypertensive agents for most patients with uncomplicated
hypertension according to JNC 8 guidelines._
3. A 68-year-old with COPD has increased sputum production and
purulence. Which antibiotic is most appropriate?
A. Azithromycin
B. Amoxicillin-clavulanate
C. Ciprofloxacin
D. Cephalexin
Rationale: Amoxicillin-clavulanate covers common COPD exacerbation
pathogens, including H. influenzae, M. catarrhalis, and S. pneumoniae._
4. Which vaccine is contraindicated in pregnancy?
A. Tdap
B. MMR
,C. Influenza (inactivated)
D. Hepatitis B
Rationale: MMR is a live vaccine and is contraindicated in pregnancy due
to potential teratogenicity._
5. A 15-year-old presents with sore throat, fever, and anterior cervical
adenopathy. Which test confirms the diagnosis of Group A streptococcal
pharyngitis?
A. Throat culture
B. Rapid antigen detection test
C. CBC
D. Monospot
Rationale: Rapid antigen detection testing (RADT) provides quick
confirmation of Group A Streptococcus infection._
6. A 54-year-old woman presents with fatigue, constipation, and dry skin.
TSH is elevated, and free T4 is low. What is the diagnosis?
A. Hyperthyroidism
B. Primary hypothyroidism
C. Secondary hypothyroidism
D. Subclinical hypothyroidism
Rationale: Elevated TSH with low free T4 indicates primary hypothyroidism
due to thyroid gland failure._
, 7. A 7-year-old child has a bark-like cough, inspiratory stridor, and
hoarseness. What is the most likely diagnosis?
A. Epiglottitis
B. Bronchiolitis
C. Croup (laryngotracheobronchitis)
D. Asthma
Rationale: Croup presents with a barking cough and inspiratory stridor,
typically caused by parainfluenza virus._
8. The most appropriate screening test for colorectal cancer in average-risk
adults starting at age 45 is:
A. Abdominal CT scan
B. Colonoscopy every 10 years
C. Stool culture
D. Flexible sigmoidoscopy every 3 years
Rationale: Colonoscopy every 10 years remains the gold standard for
colorectal cancer screening._
9. A 26-year-old presents with lower abdominal pain, cervical motion
tenderness, and mucopurulent discharge. What is the recommended
treatment?
Exam Practice Test Questions And
Correct Answers (Verified Answers) Plus
Rationales 2026 Q&A | Instant
Download Pdf
1. A 32-year-old female presents with dysuria, frequency, and urgency.
Which organism is most commonly responsible for uncomplicated urinary
tract infections?
A. Staphylococcus aureus
B. Escherichia coli
C. Pseudomonas aeruginosa
D. Enterococcus faecalis
Rationale: Escherichia coli is the most frequent cause of uncomplicated
urinary tract infections due to its uropathogenic virulence factors that
allow adherence to uroepithelial cells._
,2. A 45-year-old male with hypertension presents for a follow-up. Which
antihypertensive drug is preferred as first-line therapy in the absence of
comorbidities?
A. Beta-blocker
B. Alpha-blocker
C. Thiazide diuretic
D. Loop diuretic
Rationale: Thiazide diuretics are recommended as first-line
antihypertensive agents for most patients with uncomplicated
hypertension according to JNC 8 guidelines._
3. A 68-year-old with COPD has increased sputum production and
purulence. Which antibiotic is most appropriate?
A. Azithromycin
B. Amoxicillin-clavulanate
C. Ciprofloxacin
D. Cephalexin
Rationale: Amoxicillin-clavulanate covers common COPD exacerbation
pathogens, including H. influenzae, M. catarrhalis, and S. pneumoniae._
4. Which vaccine is contraindicated in pregnancy?
A. Tdap
B. MMR
,C. Influenza (inactivated)
D. Hepatitis B
Rationale: MMR is a live vaccine and is contraindicated in pregnancy due
to potential teratogenicity._
5. A 15-year-old presents with sore throat, fever, and anterior cervical
adenopathy. Which test confirms the diagnosis of Group A streptococcal
pharyngitis?
A. Throat culture
B. Rapid antigen detection test
C. CBC
D. Monospot
Rationale: Rapid antigen detection testing (RADT) provides quick
confirmation of Group A Streptococcus infection._
6. A 54-year-old woman presents with fatigue, constipation, and dry skin.
TSH is elevated, and free T4 is low. What is the diagnosis?
A. Hyperthyroidism
B. Primary hypothyroidism
C. Secondary hypothyroidism
D. Subclinical hypothyroidism
Rationale: Elevated TSH with low free T4 indicates primary hypothyroidism
due to thyroid gland failure._
, 7. A 7-year-old child has a bark-like cough, inspiratory stridor, and
hoarseness. What is the most likely diagnosis?
A. Epiglottitis
B. Bronchiolitis
C. Croup (laryngotracheobronchitis)
D. Asthma
Rationale: Croup presents with a barking cough and inspiratory stridor,
typically caused by parainfluenza virus._
8. The most appropriate screening test for colorectal cancer in average-risk
adults starting at age 45 is:
A. Abdominal CT scan
B. Colonoscopy every 10 years
C. Stool culture
D. Flexible sigmoidoscopy every 3 years
Rationale: Colonoscopy every 10 years remains the gold standard for
colorectal cancer screening._
9. A 26-year-old presents with lower abdominal pain, cervical motion
tenderness, and mucopurulent discharge. What is the recommended
treatment?
