Test Bank For Abrams’ Clinical Drug Therapy R
xt xt xt xt xt xt xt
tionales for Nursing Practice 12th Edition (Versio
xt xt xt xt xt xt
n 2023/2024) Geralyn Frandsen ISBN/ISSN 9781
xt xt xt xt xt
975136130.
, GRADESBOOST.COM
Chapter 1, The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
1. A woman diagnosed with obsessive–
xt xt xt xt
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is t
xt xt xt xt xt xt xt xt xt xt
he expected effect for this prescription?
xt xt xt xt xt
A. Curative effect on symptoms xt xt xt
B. Systemic effect on symptoms xt xt xt
C. Local effect on symptoms xt xt xt
D. Parenteral effect on symptoms xt xt xt
ANS: B x t
Rationale: Drugs that produce systemic effects are taken into the body, circulated through t
xt xt xt xt xt xt xt xt xt xt xt xt xt
he bloodstream to their sites of action in various body tissues, and eventually eliminated fro
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
m the body. Curative agents are given to cure a disease process. In this case, paroxetine hyd
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
rochloride will control the symptoms but not cure the disorder. Drugs with local effects, such
xt xt xt xt xt xt xt xt xt xt xt xt xt xt x
as sunscreen and local anesthetics, act mainly at the site of application. Paroxetine hydrochl
t xt xt xt xt xt xt xt xt xt xt xt xt xt
oride is not administered parenterally. Parenteral agents are administered subcutaneously, in
xt xt xt xt xt xt xt xt xt xt
tramuscularly, or intravenously. xt xt
PTS: 1 REF: p. 3, Introduction OBJ: 1 xt xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
GRADESBOOST.COM
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt
t xt xt xt xt xt xt xt xt
KEY: Integrated Process: Nursing Process
xt
x t xt xt xt
BLM: Cognitive Level: Understand NOT: Multiple Choice
xt
x t xt xt x t xt
xt
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
xt
xt xt xt xt xt xt xt xt xt xt xt xt
substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOt Mi s another name for this type of
xt
xt
.C xt xt xt xt xt xt xt xt xt xt xt
medication?
xt
A. Synthetic drug
xt
xt
xt
B. Semisynthetic drug xt
xt
C. Biotechnology drug xt
xt
D. Prototype drug xt
xt
ANS: B
xt
x t
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances t
xt
xt xt xt xt xt xt xt xt xt xt
hat have been chemically modified. Synthetic drugs are more standardized in their chemical
xt xt xt xt xt xt xt xt xt xt xt xt xt
characteristics, more consistent in their effects, and less likely to produce allergic reactions.
xt xt xt xt xt xt xt xt xt xt xt xt x
Biotechnology drugs involve manipulating DNA and RNA and recombining genes into hyb
t xt xt xt xt xt xt xt xt xt xt xt
rid molecules that can be inserted into living organisms. Prototype drugs are the first drug o
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
f a particular group to be developed.
xt xt xt xt xt xt
PTS: 1 REF: p. 3, Drug Sources OBJ: 1 xt xt xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
TOP:
t Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
KEY: x t Integrated Process: Nursing Process xt xt xt
BLM: x t Cognitive Level: Understand NOT: Multiple Choice xt xt x t xt
3. Which classification applies to morphine?
xt xt xt xt
A. Central nervous system depressant xt xt xt
B. Central nervous system stimulant xt xt xt
GRADESBOOST.COM #1 TEST BANKS WEBSITE xt xt xt xt
, GRADESBOOST.COM
C. Anti-inflammatory
D. Antihypertensive
ANS: A x t
Rationale: Drugs are classified according to their effects on particular body systems, their t
xt xt xt xt xt xt xt xt xt xt xt xt xt
herapeutic uses, and their chemical characteristics. Morphine is classified as a central nervo
xt xt xt xt xt xt xt xt xt xt xt xt
us system depressant and will produce this effect in the client. A central nervous system sti
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
mulant increases attention and raises mood. An anti-
xt xt xt xt xt xt xt
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An a
xt xt xt xt xt xt xt xt xt xt xt xt xt
ntihypertensive agent reduces blood pressure. xt xt xt xt
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ:
xt xt xt 1 xt xt xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
TOP:
t Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
KEY: x t Integrated Process: Nursing Process xt xt xt
BLM: x t Cognitive Level: Remember NOT: Multiple Choice
xt xt x t xt
4. A client is administered amoxicillin. The generic name of this medication belongs to which
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
drug group? xt
A. Selective serotonin reuptake inhibitors xt xt xt
B. Diuretics
GRADESBOOST.COM
xt
C. Penicillins
xt
D. ACE inhibitors xt
xt
ANS: C
xt
x t
Rationale: The generic name often indicates the drug group (e.g., drugs with generic names
GRADESBOOST.COM
xt
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medications th
xt
xt xt xt xt xt xt xt xt xt xt xt
at have antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics ar
xt
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
xt
e medications that increase urine output; diuretic is a broad classification, not a generic nam
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
xt
e. ACE inhibitor is the broad classification for the angiotensin receptor blockers, not the gen
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
xt
eric name. xt
xt
xt
PTS: 1 REF: p. 3, Drug Names OBJ: 2 xt xt xt
xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
xt
TOP:
t Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
KEY: x t Integrated Process: Nursing Process xt xt xt
BLM: x t Cognitive Level: Understand NOT: Multiple Choice
xt xt x t xt
5. The administration of diphenhydramine is regulated by which U.S. government agency?
xt xt xt xt xt xt xt xt xt xt
A. Public Health Service xt xt
B. Federal Trade Commission xt xt
C. Occupational Safety and Health Administration xt xt xt xt
D. Food and Drug Administration xt xt xt xt
ANS: D x t
GRADESBOOST.COM #1 TEST BANKS WEBSITE xt xt xt xt
, GRADESBOOST.COM
Rationale: The Food and Drug Administration approves drugs for over-the-
xt xt xt xt xt xt xt xt xt
counter availability, including the transfer of drugs from prescription to OTC status, and m
xt xt xt xt xt xt xt xt xt xt xt xt xt
ay require clinical trials to determine the safety and effectiveness of OTC use. The Public
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
Health Service is regulated by the state to maintain the health of individual citizens of the s
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
tate. The Federal Trade Commission regulates imports and exports throughout the nation. T
xt xt xt xt xt xt xt xt xt xt xt xt
he Occupational Safety and Health Administration regulates safety within the workplace.
xt xt xt xt xt xt xt xt xt xt
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
xt xt xt xt xt xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
TOP:
t Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
KEY: x t Integrated Process: Nursing Process xt xt xt
BLM: x t Cognitive Level: Understand NOT: Multiple Choice xt xt x t xt
6. In the U.S., the administration of anabolic steroids is regulated by which law?
xt xt xt xt xt xt xt xt xt xt xt xt
A. The Food, Drug, and Cosmetic Act of 1938
xt xt xt xt xt xt xt
B. The Comprehensive Drug Abuse Prevention and Control Act
xt xt xt xt xt xt xt
C. The Harrison Narcotic Act xt xt xt
D. The Sherley Amendment xt xt
ANS: B x t
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the manu
GRADESBOOST.COM
xt xt xt xt xt xt xt xt xt xt xt
xt
facture and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic st
xt xt xt xt xt xt xt xt xt xt
xt
eroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and
xt xt xt xt xt xt xt xt xt xt xt xt xt xt x
xt
responsibilities, giving the FDA control over drug safety. The Harrison Narcotic Act restrict
t xt xt xt xt xt xt xt xt xt xt xt xt
xt
ed the importation, manufacture, sale, and use of opium, cocaine, marijuana, and other drugs
xt xt xt xt xt xt xt xt xt xt xt xt xt x
xt
that the act d e f i Gn eRd Aa Ds E
t xt xt naSrcBoO
tiO
csSTh.eCSOhM
.Txt erley Amendment of 1912 prohibited fraudulent cl xt xt xt xt xt xt xt xt
xt
aims of drug effectiveness.
xt xt xt
xt
xt
PTS: 1 REF:
xt
p. 4, Prescription and Nonprescription Drugs OBJ: 3
xt xt xt xt xt xt
xt
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt
x t xt xt xt xt xt xt xt x
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt
t xt xt xt xt xt xt xt xt
KEY: Integrated Process: Nursing Process
xt
x t xt xt xt
BLM: Cognitive Level: Remember NOT: Multiple Choice
xt
x t xt xt x t xt
7. A nurse is responsible for maintaining an accurate count and record of the controlled su
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
bstances on the nursing division. This nursing action is regulated by which U.S. law or ag
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
ency?
A. The Food, Drug, and Cosmetic Act of 1938
xt xt xt xt xt xt xt
B. The Public Health Service xt xt xt
C. The Drug Enforcement Administration
xt xt xt
D. The Sherley Amendment xt xt x
tANS: C x t
GRADESBOOST.COM #1 TEST BANKS WEBSITE xt xt xt xt
xt xt xt xt xt xt xt
tionales for Nursing Practice 12th Edition (Versio
xt xt xt xt xt xt
n 2023/2024) Geralyn Frandsen ISBN/ISSN 9781
xt xt xt xt xt
975136130.
, GRADESBOOST.COM
Chapter 1, The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
1. A woman diagnosed with obsessive–
xt xt xt xt
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is t
xt xt xt xt xt xt xt xt xt xt
he expected effect for this prescription?
xt xt xt xt xt
A. Curative effect on symptoms xt xt xt
B. Systemic effect on symptoms xt xt xt
C. Local effect on symptoms xt xt xt
D. Parenteral effect on symptoms xt xt xt
ANS: B x t
Rationale: Drugs that produce systemic effects are taken into the body, circulated through t
xt xt xt xt xt xt xt xt xt xt xt xt xt
he bloodstream to their sites of action in various body tissues, and eventually eliminated fro
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
m the body. Curative agents are given to cure a disease process. In this case, paroxetine hyd
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
rochloride will control the symptoms but not cure the disorder. Drugs with local effects, such
xt xt xt xt xt xt xt xt xt xt xt xt xt xt x
as sunscreen and local anesthetics, act mainly at the site of application. Paroxetine hydrochl
t xt xt xt xt xt xt xt xt xt xt xt xt xt
oride is not administered parenterally. Parenteral agents are administered subcutaneously, in
xt xt xt xt xt xt xt xt xt xt
tramuscularly, or intravenously. xt xt
PTS: 1 REF: p. 3, Introduction OBJ: 1 xt xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
GRADESBOOST.COM
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt
t xt xt xt xt xt xt xt xt
KEY: Integrated Process: Nursing Process
xt
x t xt xt xt
BLM: Cognitive Level: Understand NOT: Multiple Choice
xt
x t xt xt x t xt
xt
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
xt
xt xt xt xt xt xt xt xt xt xt xt xt
substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOt Mi s another name for this type of
xt
xt
.C xt xt xt xt xt xt xt xt xt xt xt
medication?
xt
A. Synthetic drug
xt
xt
xt
B. Semisynthetic drug xt
xt
C. Biotechnology drug xt
xt
D. Prototype drug xt
xt
ANS: B
xt
x t
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances t
xt
xt xt xt xt xt xt xt xt xt xt
hat have been chemically modified. Synthetic drugs are more standardized in their chemical
xt xt xt xt xt xt xt xt xt xt xt xt xt
characteristics, more consistent in their effects, and less likely to produce allergic reactions.
xt xt xt xt xt xt xt xt xt xt xt xt x
Biotechnology drugs involve manipulating DNA and RNA and recombining genes into hyb
t xt xt xt xt xt xt xt xt xt xt xt
rid molecules that can be inserted into living organisms. Prototype drugs are the first drug o
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
f a particular group to be developed.
xt xt xt xt xt xt
PTS: 1 REF: p. 3, Drug Sources OBJ: 1 xt xt xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
TOP:
t Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
KEY: x t Integrated Process: Nursing Process xt xt xt
BLM: x t Cognitive Level: Understand NOT: Multiple Choice xt xt x t xt
3. Which classification applies to morphine?
xt xt xt xt
A. Central nervous system depressant xt xt xt
B. Central nervous system stimulant xt xt xt
GRADESBOOST.COM #1 TEST BANKS WEBSITE xt xt xt xt
, GRADESBOOST.COM
C. Anti-inflammatory
D. Antihypertensive
ANS: A x t
Rationale: Drugs are classified according to their effects on particular body systems, their t
xt xt xt xt xt xt xt xt xt xt xt xt xt
herapeutic uses, and their chemical characteristics. Morphine is classified as a central nervo
xt xt xt xt xt xt xt xt xt xt xt xt
us system depressant and will produce this effect in the client. A central nervous system sti
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
mulant increases attention and raises mood. An anti-
xt xt xt xt xt xt xt
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An a
xt xt xt xt xt xt xt xt xt xt xt xt xt
ntihypertensive agent reduces blood pressure. xt xt xt xt
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ:
xt xt xt 1 xt xt xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
TOP:
t Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
KEY: x t Integrated Process: Nursing Process xt xt xt
BLM: x t Cognitive Level: Remember NOT: Multiple Choice
xt xt x t xt
4. A client is administered amoxicillin. The generic name of this medication belongs to which
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
drug group? xt
A. Selective serotonin reuptake inhibitors xt xt xt
B. Diuretics
GRADESBOOST.COM
xt
C. Penicillins
xt
D. ACE inhibitors xt
xt
ANS: C
xt
x t
Rationale: The generic name often indicates the drug group (e.g., drugs with generic names
GRADESBOOST.COM
xt
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medications th
xt
xt xt xt xt xt xt xt xt xt xt xt
at have antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics ar
xt
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
xt
e medications that increase urine output; diuretic is a broad classification, not a generic nam
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
xt
e. ACE inhibitor is the broad classification for the angiotensin receptor blockers, not the gen
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
xt
eric name. xt
xt
xt
PTS: 1 REF: p. 3, Drug Names OBJ: 2 xt xt xt
xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
xt
TOP:
t Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
KEY: x t Integrated Process: Nursing Process xt xt xt
BLM: x t Cognitive Level: Understand NOT: Multiple Choice
xt xt x t xt
5. The administration of diphenhydramine is regulated by which U.S. government agency?
xt xt xt xt xt xt xt xt xt xt
A. Public Health Service xt xt
B. Federal Trade Commission xt xt
C. Occupational Safety and Health Administration xt xt xt xt
D. Food and Drug Administration xt xt xt xt
ANS: D x t
GRADESBOOST.COM #1 TEST BANKS WEBSITE xt xt xt xt
, GRADESBOOST.COM
Rationale: The Food and Drug Administration approves drugs for over-the-
xt xt xt xt xt xt xt xt xt
counter availability, including the transfer of drugs from prescription to OTC status, and m
xt xt xt xt xt xt xt xt xt xt xt xt xt
ay require clinical trials to determine the safety and effectiveness of OTC use. The Public
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
Health Service is regulated by the state to maintain the health of individual citizens of the s
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
tate. The Federal Trade Commission regulates imports and exports throughout the nation. T
xt xt xt xt xt xt xt xt xt xt xt xt
he Occupational Safety and Health Administration regulates safety within the workplace.
xt xt xt xt xt xt xt xt xt xt
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
xt xt xt xt xt xt
NAT: x t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt xt xt xt xt xt xt x
TOP:
t Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt xt xt xt xt xt xt xt
KEY: x t Integrated Process: Nursing Process xt xt xt
BLM: x t Cognitive Level: Understand NOT: Multiple Choice xt xt x t xt
6. In the U.S., the administration of anabolic steroids is regulated by which law?
xt xt xt xt xt xt xt xt xt xt xt xt
A. The Food, Drug, and Cosmetic Act of 1938
xt xt xt xt xt xt xt
B. The Comprehensive Drug Abuse Prevention and Control Act
xt xt xt xt xt xt xt
C. The Harrison Narcotic Act xt xt xt
D. The Sherley Amendment xt xt
ANS: B x t
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the manu
GRADESBOOST.COM
xt xt xt xt xt xt xt xt xt xt xt
xt
facture and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic st
xt xt xt xt xt xt xt xt xt xt
xt
eroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and
xt xt xt xt xt xt xt xt xt xt xt xt xt xt x
xt
responsibilities, giving the FDA control over drug safety. The Harrison Narcotic Act restrict
t xt xt xt xt xt xt xt xt xt xt xt xt
xt
ed the importation, manufacture, sale, and use of opium, cocaine, marijuana, and other drugs
xt xt xt xt xt xt xt xt xt xt xt xt xt x
xt
that the act d e f i Gn eRd Aa Ds E
t xt xt naSrcBoO
tiO
csSTh.eCSOhM
.Txt erley Amendment of 1912 prohibited fraudulent cl xt xt xt xt xt xt xt xt
xt
aims of drug effectiveness.
xt xt xt
xt
xt
PTS: 1 REF:
xt
p. 4, Prescription and Nonprescription Drugs OBJ: 3
xt xt xt xt xt xt
xt
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
xt
x t xt xt xt xt xt xt xt x
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
xt
t xt xt xt xt xt xt xt xt
KEY: Integrated Process: Nursing Process
xt
x t xt xt xt
BLM: Cognitive Level: Remember NOT: Multiple Choice
xt
x t xt xt x t xt
7. A nurse is responsible for maintaining an accurate count and record of the controlled su
xt xt xt xt xt xt xt xt xt xt xt xt xt xt
bstances on the nursing division. This nursing action is regulated by which U.S. law or ag
xt xt xt xt xt xt xt xt xt xt xt xt xt xt xt
ency?
A. The Food, Drug, and Cosmetic Act of 1938
xt xt xt xt xt xt xt
B. The Public Health Service xt xt xt
C. The Drug Enforcement Administration
xt xt xt
D. The Sherley Amendment xt xt x
tANS: C x t
GRADESBOOST.COM #1 TEST BANKS WEBSITE xt xt xt xt
