MLS HEMATOLOGY EXAM 2023-2024 ACTUAL EXAM 400 QUESTIONS AND CORRECT DETAILED ANSWERS
What is the first type of cell produced by the developing embryo? - (answer) Erythrocyte
What percentage of tissue located in the bone marrow cavities of adults is fat? - (answer) 50%
Which of the following is not characteristic of pluripotent hematopoietic stem cells? - (answer) Express
the stem marker CD13
In an adult, what are the two best areas for obtaining active bone marrow by aspiration? - (answer)
Posterior iliac crest, sternum
What is the normal ratio of myeloid to erythroid precursors in bone marrow (M:E ratio)? - (answer) 4:1
Which of the following does not accurately describe hematopoietic growth factors? - (answer) Action
of majority is lineage restricted
In the third month of gestation, what is the primary site of hematopoiesis? - (answer) Liver
The mechanism that relays information about tissue oxygen levels to erythropoietin-producing sites is
located in the: - (answer) Kidney
Antigen-independent lymphopoiesis occurs in primary lymphoid tissue located in the: - (answer)
Thymus and bone marrow
Programmed cell death is called: - (answer) Apoptosis
In what area of the bone marrow does hematopoiesis take place? - (answer) Cords
Bone marrow cellularity refers to the ration of: - (answer) Hematopoietic tissue to adipose tissue
,MLS HEMATOLOGY EXAM 2023-2024 ACTUAL EXAM 400 QUESTIONS AND CORRECT DETAILED ANSWERS
Interleukins and colony stimulating factors are cytokines produced by: - (answer) Monocytes and T
lymphocytes
What is the approximate total blood volume in an adult? - (answer) 6 L
The myeloid progenitor cell can produce cells committed to: - (answer) Granulocytic, erythrocytic,
monocytic, or megakaryocytic lineages
The largest hematopoietic cells in normal bone marrow are: - (answer) Megakaryocytes
When evaluating a bone marrow aspirate smear, which finding is considered abnormal? - (answer) The
presence of 10% myeloblasts on the cell differential count
As most blood cell lines mature, which of the following is characteristic? - (answer) Nucleus to
cytoplasm ratio (N:C) decreases
Which of the following describes thrombopoietin (TPO)? - (answer) Hormone produced by the liver
that stimulates megakaryopoiesis
When the hepatic phase of fetal life is reactivated in an adult, hematopoiesis can be termed: - (answer)
Myeloid metaplasia or extramedullary
What is the average life span of a normal red blood cell? - (answer) 120 days
The Na+-K+ cation pump is an important mechanism in keeping the red blood cell intact. Its function is
to maintain a high level of: - (answer) Intracellular K+
Which of the following depicts the structure of the hemoglobin molecule? - (answer) Four heme
groups, four globin chains
, MLS HEMATOLOGY EXAM 2023-2024 ACTUAL EXAM 400 QUESTIONS AND CORRECT DETAILED ANSWERS
Which of the following describes the process known as culling? - (answer) Removal of abnormal red
cells by spleen
Hemoglobin forms that are incapable of oxygen transport include: - (answer) Carboxyhemoglobin and
methemoglobin
The majority of iron found in an adult is a constituent of: - (answer) Hemoglobin
A senescent red blood cell is one that has: - (answer) Lived its life span
What red cell morphologic abnormality is described by the term "poikilocytosis"? - (answer)
Deviations from normal shape
Howell-Jolly bodies are composed of: - (answer) DNA
When spherocytes are reported, what is observed on the peripheral blood smear? - (answer) Red cells
without a central pallor
The red cells found in lead poisoning characteristically exhibit coarse granules composed of __________
that are reported as _________. - (answer) Aggregated ribosomes; basophilic stippling
Rouleaux of red blood cells when seen in the monolayer of a blood smear is characteristic of: -
(answer) Multiple myeloma
Which of the following is most frequently associated with the inclusion bodies seen in Color Plate 1? -
(answer) Post-splenectomy
Which of the following statements about iron absorption is true? - (answer) Absorption increases
when erythropoietic activity increases
What is the first type of cell produced by the developing embryo? - (answer) Erythrocyte
What percentage of tissue located in the bone marrow cavities of adults is fat? - (answer) 50%
Which of the following is not characteristic of pluripotent hematopoietic stem cells? - (answer) Express
the stem marker CD13
In an adult, what are the two best areas for obtaining active bone marrow by aspiration? - (answer)
Posterior iliac crest, sternum
What is the normal ratio of myeloid to erythroid precursors in bone marrow (M:E ratio)? - (answer) 4:1
Which of the following does not accurately describe hematopoietic growth factors? - (answer) Action
of majority is lineage restricted
In the third month of gestation, what is the primary site of hematopoiesis? - (answer) Liver
The mechanism that relays information about tissue oxygen levels to erythropoietin-producing sites is
located in the: - (answer) Kidney
Antigen-independent lymphopoiesis occurs in primary lymphoid tissue located in the: - (answer)
Thymus and bone marrow
Programmed cell death is called: - (answer) Apoptosis
In what area of the bone marrow does hematopoiesis take place? - (answer) Cords
Bone marrow cellularity refers to the ration of: - (answer) Hematopoietic tissue to adipose tissue
,MLS HEMATOLOGY EXAM 2023-2024 ACTUAL EXAM 400 QUESTIONS AND CORRECT DETAILED ANSWERS
Interleukins and colony stimulating factors are cytokines produced by: - (answer) Monocytes and T
lymphocytes
What is the approximate total blood volume in an adult? - (answer) 6 L
The myeloid progenitor cell can produce cells committed to: - (answer) Granulocytic, erythrocytic,
monocytic, or megakaryocytic lineages
The largest hematopoietic cells in normal bone marrow are: - (answer) Megakaryocytes
When evaluating a bone marrow aspirate smear, which finding is considered abnormal? - (answer) The
presence of 10% myeloblasts on the cell differential count
As most blood cell lines mature, which of the following is characteristic? - (answer) Nucleus to
cytoplasm ratio (N:C) decreases
Which of the following describes thrombopoietin (TPO)? - (answer) Hormone produced by the liver
that stimulates megakaryopoiesis
When the hepatic phase of fetal life is reactivated in an adult, hematopoiesis can be termed: - (answer)
Myeloid metaplasia or extramedullary
What is the average life span of a normal red blood cell? - (answer) 120 days
The Na+-K+ cation pump is an important mechanism in keeping the red blood cell intact. Its function is
to maintain a high level of: - (answer) Intracellular K+
Which of the following depicts the structure of the hemoglobin molecule? - (answer) Four heme
groups, four globin chains
, MLS HEMATOLOGY EXAM 2023-2024 ACTUAL EXAM 400 QUESTIONS AND CORRECT DETAILED ANSWERS
Which of the following describes the process known as culling? - (answer) Removal of abnormal red
cells by spleen
Hemoglobin forms that are incapable of oxygen transport include: - (answer) Carboxyhemoglobin and
methemoglobin
The majority of iron found in an adult is a constituent of: - (answer) Hemoglobin
A senescent red blood cell is one that has: - (answer) Lived its life span
What red cell morphologic abnormality is described by the term "poikilocytosis"? - (answer)
Deviations from normal shape
Howell-Jolly bodies are composed of: - (answer) DNA
When spherocytes are reported, what is observed on the peripheral blood smear? - (answer) Red cells
without a central pallor
The red cells found in lead poisoning characteristically exhibit coarse granules composed of __________
that are reported as _________. - (answer) Aggregated ribosomes; basophilic stippling
Rouleaux of red blood cells when seen in the monolayer of a blood smear is characteristic of: -
(answer) Multiple myeloma
Which of the following is most frequently associated with the inclusion bodies seen in Color Plate 1? -
(answer) Post-splenectomy
Which of the following statements about iron absorption is true? - (answer) Absorption increases
when erythropoietic activity increases
