Clinical Correlation: Cystic Fibrosis 8/22
1. disease of bronchi: cystic fibrosis
2. complications from failure to diagnose CF: hypochloremia (alkalosis)
hyponatremia (dehydration)
hypoproteinemia (protein calorie malnutrition)
vitamin E deficency (hemolytic anemia)
vitamin K deficiency (bleeding diathesis)
zinc deficiency (acrodermatitis)
3. clinical clues to diagnose CF: meconium ileus
failure to thrive
chronic respiratory and sinus disease
rectal prolapse
polyps
new born screening
4. meconium ileus: In cystic fibrosis, meconium plug obstructs intestine preventing stool passage at birth.
5. clubbing in CF patient: nails are curved back
1/2
1. disease of bronchi: cystic fibrosis
2. complications from failure to diagnose CF: hypochloremia (alkalosis)
hyponatremia (dehydration)
hypoproteinemia (protein calorie malnutrition)
vitamin E deficency (hemolytic anemia)
vitamin K deficiency (bleeding diathesis)
zinc deficiency (acrodermatitis)
3. clinical clues to diagnose CF: meconium ileus
failure to thrive
chronic respiratory and sinus disease
rectal prolapse
polyps
new born screening
4. meconium ileus: In cystic fibrosis, meconium plug obstructs intestine preventing stool passage at birth.
5. clubbing in CF patient: nails are curved back
1/2
