Test Bank for Modern Blood Banking & Transfusion Practices 7th Edition Author: Denise M. Harmening| 9780803668881| All Chapters 1-29| LATEST VERSION

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, Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple ChoiceXt


Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
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a. Pentose phosphate shunt c. Glycolysis Xt Xt


b. Luebering-Rapoport shunt d. Methemoglobin reductase Xt X t Xt




2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed.
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The unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most
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accurate?
a. The unit of blood should be discarded immediately.
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b. The unit of blood can be returned to inventory.
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c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
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d. The unit of blood must be transfused with 24 hours.
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3. What is the average diameter of a platelet?
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a. 5 to 10 µm Xt Xt Xt c. 1 to 2 µm Xt Xt Xt


b. 2 to 4 µm Xt Xt Xt d. 4 to 6 µm
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4. In the normal hemoglobin-
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oxygen dissociation curve, what percentage of oxygen is released to the tissues when PO2 averages
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40 mm Hg? Xt Xt


a. 75% c. 100%
b. 25% d. 50% X t




5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet countXt Xt


b. Initial pH d. All of the above
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6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a r
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esult of loss of RBC membrane?
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a. Spherocytes c. Burr cells Xt


b. Target cells d. Schistocytes
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7. What does the term autologous transfusion refer to?
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a. A parent donating blood for his or her child
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b. An individual donating blood for a friend
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c. An individual donating blood for a relative
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d. An individual donating blood for his or her own transfusion
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8. What is the primary function of hemoglobin?
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a. Iron metabolism c. Oxygen transport
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b. Porphyrin synthesis d. Signal transduction Xt X t Xt




9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment.
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b. RBC membrane. d. Hemoglobin structure.
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, X t 10. What is the correct biochemical composition of the RBC membrane?
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a. 52% protein, 40% lipid, 8% carbohydrate
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b. 40% protein, 8% lipid, 52% carbohydrate
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c. 8% protein, 52% lipid, 40% carbohydrate
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d. 8% lipid, 40% carbohydrate, 52% protein
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X t 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
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except:
a. Decreased pH. c. Increased ATP level.
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b. Loss of red blood cell function. Xt d. Decreased glucose consumption.
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Xt 12. Which red blood cell preservative has a storage time of 35 days?
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a. ACD c. AS-1
b. CPDA-1 d. CPD X t X t




Xt 13. The RBC membrane is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. X t




Xt 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released fro
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m the bone marrow?
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a. 30% c. 10%
b. 50% d. 25% X t X t




Xt 15. What is the major biochemical consideration in platelet storage?
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a. Glucose metabolism c. Production of carbon dioxide
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b. Oxygen supply d. Regulation of pH
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Xt 16. What would the hemoglobin-
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oxygen dissociation curve depict in a patient exhibiting clinical signs of alkalosis?
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a. Normal c. Shift to the right Xt Xt Xt


b. Shift to the left Xt d. None of the above
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X t 17. Name the main lipid components of a red blood cell membrane.
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a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A X t Xt




X t 18.X t The ABO blood groups were discovered in 1901 by whom?
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a. Charles Drew c. Loutit and Mollison
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b. Karl Landsteiner Xt d. Edward Lindeman X t Xt




X t 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in
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the corner of the department until discovered 36 hours later. What would the appropriate action be for th
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e blood banker?
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a. If the temperature in the box was 22 +/-
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2°C and the platelet swirl seemed OK, it would be OK to accept the unit into invento
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ry.
b. The platelets have fallen outside the supplier’s quality assurance. The unit should be
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discarded because the pH has probably dropped too low and platelet activation has b
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een compromised. Xt


c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
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