NR 546 Midterm and NR 546 Final PRACTICE
EXAMS – NR 546 Advanced Pharmacology –
Psychopharmacology for the PMHNP Exam Practice
Guide – 180 Questions and Correct Answers
Contents
NR 546 Midterm Practice Exam (100 Questions) .....................................................1
NR 546 Final Practice Test (80 Questions..............................................................23
NR 546 Midterm Practice Exam (100 Questions)
prescribed vortioxetine for his depression. What does the PMHNP need to
remember when prescribing this drug?
A. The dosage of the drug will need to be increased
B. The dosage needs to begin at half then increase over a 2-week period
C. The dosage should not exceed ½ of the usual recommended dose
D. An adjunct medication will need to be prescribed until the dosage can be
reduced
C. The dosage should not exceed ½ of the usual recommended dose
Which of the following mechanisms would you associate with an antagonist drug
action?
A. A drug that binds postsynaptic receptors and mimics the effect of the
neurotransmitter.
B. A drug that binds and blocks normal auto receptor function.
C. A drug that increases the enzymatic synthesis of neurotransmitters.
D. A drug that binds postsynaptic receptors and blocks the normal action of the
neurotransmitter.
D. A drug that binds postsynaptic receptors and blocks the normal action of the
neurotransmitter.
pg. 1
,A court order inpatient hospitalization was ordered for a patient who is considered
a danger to themselves and other. Which ethical issue is being addressed?
A. Informed consent
B. Off labeling prescription
C. Compliance
D. Restrictive methods
C. Compliance
A patient who recently started on a first generation antipsychotic reports sexual
dysfunction and nipple discharge. Which of the following actions by the PMHNP
is appropriate?
A. The PMHNP orders blood test to examine the patient's prolactin level.
B. The PMHNP states this is a normal response to treatment and these symptoms
will decrease with time.
C. The PMHNP asks the patient if they are taking any OTC supplements.
D. The PMHNP educated the patient on EPS and informs the patient that they will
have to discontinue their medication.
A. The PMHNP orders blood test to examine the patient's prolactin level.
The PHMNP recognizes which of the following medication as an atypical
antipsychotic?
A. chlorpromazine
B. aripiprazole
C. haloperidol
D. mesoridazine
B. aripiprazole
Which of the following mediation is a first generation antipsychotic?
A. risperidone
B. olanzapine
C. thiothixene
D. cariprazine
C. thiothixene
pg. 2
,Which second-generation antipsychotic requires routine absolute neutrophil count
monitoring?
A. Brexpiprazole
B. Clozapine
C. Risperidone
D. Ziprasidone
B. Clozapine
What is the expected outcome for a patient who is considered a "intermediate
metabolizer"?
A. No need for medication dosage readjustments
B. Increased risk for drug to drug reactions
C. Provider increasing drug dosages
D. Subtherapuetic drug levels
B. Increased risk for drug to drug reactions
Which of the following is true regarding epigenetic changes?
A. Epigenetic changes are reversible.
B. Epigenetic changes, changes the DNA and how the body reacts to the DNA
sequence.
C. Epigenetic changes are not linked to mental health conditions.
D. When combined with genetic risks, epigenetic changes decreased the risk for a
psychiatric disease.
A. Epigenetic changes are reversible.
Which of the following brain structures is involved in voluntary motor
movements?
A. Basal ganglia
B. Prefrontal cortex
C. Amygdala
D. Limbic system
A. Basal ganglia
pg. 3
, Obtaining consent from a guardian of a patient who has limited cognitive
capabilities or are incompetent to make decisions represents which ethical
principle?
A. Informed consent
B. Compliance
C. Off label prescribing
D. Confidentiality
B. Compliance
Lack of medication access and the increasing costs of medication is which type of
factor contributing to medication non adherence?
A. Provider
B. Environmental
C. Structural
D. Client
C. Structural
Which of the following is an enzyme inhibitor?
A. Sulfaurea
B. Smoking
C. Rifampin
D. Sulfamide
D. Sulfamide
A 22-year-old patient recently diagnosed with bipolar disorder and states "I'm not
crazy" and is refusing to take his prescribed medication. Which type of factor is
contributing to this patient's nonadherence?
A. Client factors
B. Clinician factors
C. Structural factors
D. Environmental factors
C. Structural factors
pg. 4
EXAMS – NR 546 Advanced Pharmacology –
Psychopharmacology for the PMHNP Exam Practice
Guide – 180 Questions and Correct Answers
Contents
NR 546 Midterm Practice Exam (100 Questions) .....................................................1
NR 546 Final Practice Test (80 Questions..............................................................23
NR 546 Midterm Practice Exam (100 Questions)
prescribed vortioxetine for his depression. What does the PMHNP need to
remember when prescribing this drug?
A. The dosage of the drug will need to be increased
B. The dosage needs to begin at half then increase over a 2-week period
C. The dosage should not exceed ½ of the usual recommended dose
D. An adjunct medication will need to be prescribed until the dosage can be
reduced
C. The dosage should not exceed ½ of the usual recommended dose
Which of the following mechanisms would you associate with an antagonist drug
action?
A. A drug that binds postsynaptic receptors and mimics the effect of the
neurotransmitter.
B. A drug that binds and blocks normal auto receptor function.
C. A drug that increases the enzymatic synthesis of neurotransmitters.
D. A drug that binds postsynaptic receptors and blocks the normal action of the
neurotransmitter.
D. A drug that binds postsynaptic receptors and blocks the normal action of the
neurotransmitter.
pg. 1
,A court order inpatient hospitalization was ordered for a patient who is considered
a danger to themselves and other. Which ethical issue is being addressed?
A. Informed consent
B. Off labeling prescription
C. Compliance
D. Restrictive methods
C. Compliance
A patient who recently started on a first generation antipsychotic reports sexual
dysfunction and nipple discharge. Which of the following actions by the PMHNP
is appropriate?
A. The PMHNP orders blood test to examine the patient's prolactin level.
B. The PMHNP states this is a normal response to treatment and these symptoms
will decrease with time.
C. The PMHNP asks the patient if they are taking any OTC supplements.
D. The PMHNP educated the patient on EPS and informs the patient that they will
have to discontinue their medication.
A. The PMHNP orders blood test to examine the patient's prolactin level.
The PHMNP recognizes which of the following medication as an atypical
antipsychotic?
A. chlorpromazine
B. aripiprazole
C. haloperidol
D. mesoridazine
B. aripiprazole
Which of the following mediation is a first generation antipsychotic?
A. risperidone
B. olanzapine
C. thiothixene
D. cariprazine
C. thiothixene
pg. 2
,Which second-generation antipsychotic requires routine absolute neutrophil count
monitoring?
A. Brexpiprazole
B. Clozapine
C. Risperidone
D. Ziprasidone
B. Clozapine
What is the expected outcome for a patient who is considered a "intermediate
metabolizer"?
A. No need for medication dosage readjustments
B. Increased risk for drug to drug reactions
C. Provider increasing drug dosages
D. Subtherapuetic drug levels
B. Increased risk for drug to drug reactions
Which of the following is true regarding epigenetic changes?
A. Epigenetic changes are reversible.
B. Epigenetic changes, changes the DNA and how the body reacts to the DNA
sequence.
C. Epigenetic changes are not linked to mental health conditions.
D. When combined with genetic risks, epigenetic changes decreased the risk for a
psychiatric disease.
A. Epigenetic changes are reversible.
Which of the following brain structures is involved in voluntary motor
movements?
A. Basal ganglia
B. Prefrontal cortex
C. Amygdala
D. Limbic system
A. Basal ganglia
pg. 3
, Obtaining consent from a guardian of a patient who has limited cognitive
capabilities or are incompetent to make decisions represents which ethical
principle?
A. Informed consent
B. Compliance
C. Off label prescribing
D. Confidentiality
B. Compliance
Lack of medication access and the increasing costs of medication is which type of
factor contributing to medication non adherence?
A. Provider
B. Environmental
C. Structural
D. Client
C. Structural
Which of the following is an enzyme inhibitor?
A. Sulfaurea
B. Smoking
C. Rifampin
D. Sulfamide
D. Sulfamide
A 22-year-old patient recently diagnosed with bipolar disorder and states "I'm not
crazy" and is refusing to take his prescribed medication. Which type of factor is
contributing to this patient's nonadherence?
A. Client factors
B. Clinician factors
C. Structural factors
D. Environmental factors
C. Structural factors
pg. 4
