Final Exam: NR546 / NR 546 (Latest
Update ) Advanced
Pharmacology: Psychopharmacology
for the Psychiatric-Mental Health
Nurse Practitioner | Questions and
Answers | Grade A | 100% Correct –
Chamberlain
Question:
Lurasidone (Latuda) should be taken with:
Answer:
food, at least 350 calories, for maximum absorption
Question:
Lithium carbonate (Lithobid) starting dose is reduced by at least 50% in
clients with ______________
Answer:
renal impairment
,Question:
Lithium levels can be increased by ___________and_____________ and
decreased by ___________ and __________.
Answer:
NSAIDs, ACE inhibitors,
caffeine, mania
Question:
lab tests required for: Lithium
Answer:
serum lithium level
renal function
thyroid function
Rationale: Lithium has a narrow therapeutic index and should be monitored
carefully. Serum levels should be evaluated 5 days after any dosage change and
regularly at 6-month intervals. Lithium can cause renal and thyroid toxicity.
Renal and thyroid function should be evaluated every 6 months.
,Question:
lab tests required for: Valproic acid (Depakote)
Answer:
serum valproate level
liver function
CBC
Rationale: Valproic acid and its derivatives can cause leukopenia,
thrombocytopenia, and hepatotoxicity. Monitor CBC and liver function tests
(LFTs) every 3 months for 1 year and then annually.
Question:
lab tests required for: Carbamazepine
Answer:
serum carbamazepine level
renal function
liver function
CBC
Rationale: Carbamazepine can cause blood dyscrasias, hepatotoxicity, and
renal failure. Order a CBC, LFT, and renal function every 3 months for 1 year
and then annually.
, Question:
lab tests required for: Atypical antipsychotic medications
Answer:
CBC
HbA1C
Rationale: Atypical antipsychotics can cause increased blood glucose and an
increased risk of developing diabetes mellitus (DM) II. Measure HbA1C every
3 months for 1 year and then annually. Certain medications, such as
Clozapine, may cause blood dyscrasias and CBC should be monitored closely.
Question:
Medications for Bipolar Disorder Lifespan Considerations: Pregnancy
Answer:
-Lithium, valproic acid, and carbamazepine are teratogenic and are
contraindicated during pregnancy.
-Lurasidone has been used in pregnancy without teratogenic effects.
Question:
Medications for Bipolar Disorder Lifespan Considerations: Breast Feeding
Answer:
Avoid breastfeeding for clients prescribed carbamazepine, lithium, and
lamotrigine.
Update ) Advanced
Pharmacology: Psychopharmacology
for the Psychiatric-Mental Health
Nurse Practitioner | Questions and
Answers | Grade A | 100% Correct –
Chamberlain
Question:
Lurasidone (Latuda) should be taken with:
Answer:
food, at least 350 calories, for maximum absorption
Question:
Lithium carbonate (Lithobid) starting dose is reduced by at least 50% in
clients with ______________
Answer:
renal impairment
,Question:
Lithium levels can be increased by ___________and_____________ and
decreased by ___________ and __________.
Answer:
NSAIDs, ACE inhibitors,
caffeine, mania
Question:
lab tests required for: Lithium
Answer:
serum lithium level
renal function
thyroid function
Rationale: Lithium has a narrow therapeutic index and should be monitored
carefully. Serum levels should be evaluated 5 days after any dosage change and
regularly at 6-month intervals. Lithium can cause renal and thyroid toxicity.
Renal and thyroid function should be evaluated every 6 months.
,Question:
lab tests required for: Valproic acid (Depakote)
Answer:
serum valproate level
liver function
CBC
Rationale: Valproic acid and its derivatives can cause leukopenia,
thrombocytopenia, and hepatotoxicity. Monitor CBC and liver function tests
(LFTs) every 3 months for 1 year and then annually.
Question:
lab tests required for: Carbamazepine
Answer:
serum carbamazepine level
renal function
liver function
CBC
Rationale: Carbamazepine can cause blood dyscrasias, hepatotoxicity, and
renal failure. Order a CBC, LFT, and renal function every 3 months for 1 year
and then annually.
, Question:
lab tests required for: Atypical antipsychotic medications
Answer:
CBC
HbA1C
Rationale: Atypical antipsychotics can cause increased blood glucose and an
increased risk of developing diabetes mellitus (DM) II. Measure HbA1C every
3 months for 1 year and then annually. Certain medications, such as
Clozapine, may cause blood dyscrasias and CBC should be monitored closely.
Question:
Medications for Bipolar Disorder Lifespan Considerations: Pregnancy
Answer:
-Lithium, valproic acid, and carbamazepine are teratogenic and are
contraindicated during pregnancy.
-Lurasidone has been used in pregnancy without teratogenic effects.
Question:
Medications for Bipolar Disorder Lifespan Considerations: Breast Feeding
Answer:
Avoid breastfeeding for clients prescribed carbamazepine, lithium, and
lamotrigine.
