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Name at least 3 abnormalities on bloodwork you would expect to see in a dog
with cushings disease ---------CORRECT ANSWER-----------------1 stress leukogram
2 elevated PCV
3 elevated ALP
4 elevated cholesterol
5 elevated glucose
6 low BUN
7 low USG
What is the most common cause of cushing disease in dogs ---------CORRECT
ANSWER-----------------85% pituitary dependent (pituitary gland adenoma)
15 % adrenal gland hyperplasia (50/50 benign/ malignant)
Low dose dex diagnostic shows that cushing's is pituitary dependent if (low/high)
at 4 hours and (low/high) at 8 hours ---------CORRECT ANSWER-----------------low at
4 hours
high at 8 hours
,Name at least 3 blood work abnormalities consistent with addison's disease --------
-CORRECT ANSWER-----------------1 Na:K < 27
2 elevated calcium
3 low chloride
4 low glucose
5 low USG
What is the most common cause of addison's disease ---------CORRECT ANSWER---
--------------1 primary adrenal problem- idiopathic/ immune mediated attack of
adrenals
2 pituitary ACTH deficiency- iatrogenic
What are 3 bloodwork abnormalities seen with hypothyroidism ---------CORRECT
ANSWER-----------------1 hypercholesterolemia
2 elevated CL
3 non regenerative anemia
How is hypothyroidism diagnosed ---------CORRECT ANSWER-----------------High
TSH, Low T4 and T3
Total T4 screening- low resting levels
Free T4 by electrodialysis
TSH stim test- non responsive T3/T4, high TSH
,What is the most common cause of hypothyroidism ---------CORRECT ANSWER------
-----------1 95% thyroid problem (idiopathic atrophy)
2 pituitary problem- no TSH
3 hypothalamic- no TRH
A dog presents with a history of PUPD and nocturia. owners are very sure this is
not behavioral. there is no glycosuria and no azotemia. CBC chem UA are normal
aside from a USG of 1.006. what is your top differential and what diagnostic test
would you run ---------CORRECT ANSWER-----------------diabetes insipidus
water deprivation test- only psychogenic can concentrate
water + ADH- central concentrates
gradual water deprivation- medullary wash out
What are at least 2 possible causes of diabetes inspidus ---------CORRECT
ANSWER-----------------1 nephrogenic DI- inability of renal tubules to respond to
ADH
2 central pituitary DI- problem with ADH release
3 central hypothalamus DI-problem with ADH vasopressin production
4 psychogenic- excessive water intake, disorder of thurst centers
, Production/ release of vasopressin is controlled by serum ____ and blood volume
---------CORRECT ANSWER-----------------osmolality
Treatment of choice for central diabetes insipidus ---------CORRECT ANSWER--------
---------vasopressin, unlimited water
Name at least 4 differentials for hypercalcemia ---------CORRECT ANSWER------------
-----1 excesss vit D
2 Renal
3 addison's
4 growing/ granulomatous
5 osteolytic
6 neoplasia
7 hyperparathyroidism
Name at least 1 way to treat hypercalcemia, aside from addressing the underlying
cause ---------CORRECT ANSWER-----------------1 calcitonin- hypeprvitaminosis D
2 sodium bicarb - Decreases ionized calcium levels
3 IV fluids NaCl
4 dex/ pred- steroids dec Ca absorption in gut, promote calciuresis
5 furosemide - if well hydrated