UPDATED ACTUAL Questions and
CORRECT Answers
a psychological disorder characterized by delusions, hallucinations, disorganized speech, and/or
diminished inappropriate emotional expression. - CORRECT ANSWER - Schizophrenia
The signs and symptoms of schizophrenia are traditionally separated into 2 groups: positive
(delusions, hallucinations, and disorganized speech or behavior) and negative (flat affect,
avolition, anhedonia, poor attention, and alogia). - CORRECT ANSWER - signs and
symptoms of schizophrenia
a decline in both cognitive and social functioning that often precedes the development of florid
psychosis. - CORRECT ANSWER - Schizophrenia is associated with
The exact etiology of schizophrenia is unknown, although it is thought to be linked to an increase
in dopaminergic activity.
No single etiological factor is responsible for schizophrenia. - CORRECT ANSWER -
Etiology of Schizophrenia
Treatment includes antipsychotics in conjunction with behavioral therapy. - CORRECT
ANSWER - Treatment of Schizophrenia
Schizophrenia is a chronic serious mental disorder characterized by loss of contact with reality
and manifested by two main symptoms: hallucinations and delusions. - CORRECT
ANSWER - Schizophrenia definition
Men and women are equally affected, but with a slight difference in the age of onsetMen:
average age of onset = 23 years Women: average age of onset = 26 years - CORRECT
ANSWER - onset of schizophrenia
, The disorder manifests when a person with a genetic predisposition is exposed to one of many
environmental stressors.
- genetic predisposition
- environmental stressors - CORRECT ANSWER - Etiological factors of schizophrenia
Environmental stressors are believed to be triggers of schizophrenia rather than true causes of the
disorder.
-Childhood trauma
- Residence in an urban area
- Social isolation
-Frequent cannabis use in early adolescence
- Migration
- Poverty
- Stress and psychosocial factors
- Birth in late winter or early spring
-Advanced paternal age at conception - CORRECT ANSWER - Environmental Stressors
of Schizophrenia
Genetic and environmental risk factors appear to act via a common pathway
of disrupting the function of 1 or more neurotransmitter components.
Dopaminergic theory: Almost all drugs with antipsychotic properties block the dopaminergic D2
receptor.
However, antipsychotics are only 70% effective and clozapine, the most effective antipsychotic
for treating schizophrenia, is a weak D2 antagonist.
Hyperactivity of dopamine D2 receptor neurotransmission in subcortical, and limbic brain
regions contribute to the positive symptoms of schizophrenia. Hypo functionality of dopamine
D1 receptor neurotransmission in the prefrontal cortex contributes to both negative and cognitive
symptoms. - CORRECT ANSWER - Pathophysiology of schizophrenia part 1
Other theories: