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WGU D115 MASTER SET-ADVANCED
PATHOPHYSIOLOGY FOR THE
ADVANCED PRACTICE NURSE / ACTUAL
EXAM TEST STUDY GUIDE / (340+ Q&A)
ACCURATE EXPERT VERIFIED FOR
GUARANTEED PASS / LATEST UPDATE
Questions and Correct Answers/ Latest
Update / Already Graded
Which type of genetic disease affects males more frequently than
females?
Ans: Sex-Linked recessive. Since males only have one X and
one Y, if the affected chromosome has the illness, i t will be
expressed.
In which two conditions are chromosomal abnormalities the leading
known cause?
Ans: Intellectual disability and fetal miscarriage. Chromosome
abnormalities are the leading known cause of intellectual
disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies?
All rights reserved © 2025/ 2026 |
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Ans: Chorionic villus sampling (CVS), amniocentesis, and
preimplantation genetic testing (PGT) are examples of prenatal
diagnostic studies and are performed in vitro. CVS is a form of
genetic testing that provides genetic information found in utero
and is usually performed between weeks 11 and 14 of
pregnancy. An amniocentesis is a form of genetic testing that
evaluates amniotic fluid and is usually performed during the
second trimester, between weeks 15 and 20 of pregnancy. PGT
is performed on the embryo prior to implantation.
Which genetic disorder is characterized by the presence of a zygote
having one chromosome with a normal complement of genes and one
chromosome with a missing gene?
Ans: Cri du chat syndrome (translated as "cry of the cat") is
caused by a DNA deletion. This term describes the cry often
heard from a baby affected by the syndrome. Cri du chat
syndrome can present as a microcephalic, low birth -weight
baby with a piercing cry.
How can an X-linked recessive disease skip generations?
Ans: The disease can be transmitted through female carriers.
Since females have two copies of the X chromosome, the
mother may provide an unaffected X to a daughter or son.
All rights reserved © 2025/ 2026 |
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Furthermore, a daughter may not show signs of the disease
because she has the other X (the only X the father can give to a
female) to cancel it out.
Which type of risk is referred to as the ratio of the disease rate among
the entire population to the disease rate in an unexposed population?
Ans: Relative risk is a ratio of probability, not an actual
occurrence of disease.
What are the empirical risks for most multifactorial diseases based on?
Ans: Many factors from lifestyle to genetics affect
multifactorial diseases. Observation and evaluation of each
case individually provides the most thorough and accurate
assessment.
What refers to the silenced gene of a gene pair.
Ans: The imprinted gene is the silent gene of a gene pair.
What is the primary reason that some older adults have impaired
inflammation and wound healing?
Ans: The underlying chronic illness exists.
All rights reserved © 2025/ 2026 |
, Page |4
A generalized inflammatory response seen in chronic illness
depletes the body's reserves to fight against illn ess.
Which cells are the body's primary defense against parasite invasion?
Ans: Eosinophils are the body's primary defense against
parasites.
What Phagocytes bacteria?
Ans: Macrophages work by eating or phagocytosing bacteria.
What is the first response to a foreign pathogen?
Ans: Helper T cells
Which characteristic is the most important determinant of
immunogenicity when considering the antigen?
Ans: Immunogenicity is primarily based on the ability to
recognize something foreign.
How are erythrocytes destroyed when mismatched blood is
administered, causing an ABO incompatibility?
All rights reserved © 2025/ 2026 |
WGU D115 MASTER SET-ADVANCED
PATHOPHYSIOLOGY FOR THE
ADVANCED PRACTICE NURSE / ACTUAL
EXAM TEST STUDY GUIDE / (340+ Q&A)
ACCURATE EXPERT VERIFIED FOR
GUARANTEED PASS / LATEST UPDATE
Questions and Correct Answers/ Latest
Update / Already Graded
Which type of genetic disease affects males more frequently than
females?
Ans: Sex-Linked recessive. Since males only have one X and
one Y, if the affected chromosome has the illness, i t will be
expressed.
In which two conditions are chromosomal abnormalities the leading
known cause?
Ans: Intellectual disability and fetal miscarriage. Chromosome
abnormalities are the leading known cause of intellectual
disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies?
All rights reserved © 2025/ 2026 |
, Page |2
Ans: Chorionic villus sampling (CVS), amniocentesis, and
preimplantation genetic testing (PGT) are examples of prenatal
diagnostic studies and are performed in vitro. CVS is a form of
genetic testing that provides genetic information found in utero
and is usually performed between weeks 11 and 14 of
pregnancy. An amniocentesis is a form of genetic testing that
evaluates amniotic fluid and is usually performed during the
second trimester, between weeks 15 and 20 of pregnancy. PGT
is performed on the embryo prior to implantation.
Which genetic disorder is characterized by the presence of a zygote
having one chromosome with a normal complement of genes and one
chromosome with a missing gene?
Ans: Cri du chat syndrome (translated as "cry of the cat") is
caused by a DNA deletion. This term describes the cry often
heard from a baby affected by the syndrome. Cri du chat
syndrome can present as a microcephalic, low birth -weight
baby with a piercing cry.
How can an X-linked recessive disease skip generations?
Ans: The disease can be transmitted through female carriers.
Since females have two copies of the X chromosome, the
mother may provide an unaffected X to a daughter or son.
All rights reserved © 2025/ 2026 |
, Page |3
Furthermore, a daughter may not show signs of the disease
because she has the other X (the only X the father can give to a
female) to cancel it out.
Which type of risk is referred to as the ratio of the disease rate among
the entire population to the disease rate in an unexposed population?
Ans: Relative risk is a ratio of probability, not an actual
occurrence of disease.
What are the empirical risks for most multifactorial diseases based on?
Ans: Many factors from lifestyle to genetics affect
multifactorial diseases. Observation and evaluation of each
case individually provides the most thorough and accurate
assessment.
What refers to the silenced gene of a gene pair.
Ans: The imprinted gene is the silent gene of a gene pair.
What is the primary reason that some older adults have impaired
inflammation and wound healing?
Ans: The underlying chronic illness exists.
All rights reserved © 2025/ 2026 |
, Page |4
A generalized inflammatory response seen in chronic illness
depletes the body's reserves to fight against illn ess.
Which cells are the body's primary defense against parasite invasion?
Ans: Eosinophils are the body's primary defense against
parasites.
What Phagocytes bacteria?
Ans: Macrophages work by eating or phagocytosing bacteria.
What is the first response to a foreign pathogen?
Ans: Helper T cells
Which characteristic is the most important determinant of
immunogenicity when considering the antigen?
Ans: Immunogenicity is primarily based on the ability to
recognize something foreign.
How are erythrocytes destroyed when mismatched blood is
administered, causing an ABO incompatibility?
All rights reserved © 2025/ 2026 |
