Berne and Levy Physiology 7th Edition KoeppenTest Bank
d d d d d d d
, Koeppen: Berne and Levy Physiology, 7th Edition
d d d d d d
Chapter 01: Principles of Cell
d d d d
FunctionTest Bank
d d
Multiple Choice d
1. The subcellular structure that degrades proteins is called the:
d d d d d d d d
A. Tight junction d
B. Mitochondria
C. Lysosome
D. Plasma membrane d
E. Ribosome
ANS: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The following
d d d d d d d d d d d d d d d d
ddata are obtained: d d
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents the
d d d d d d d d d d d d d d d d d
cell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell is
d d d d d d d d d d d d d d d
markedly reduced. According to this information, which of the followingmechanisms is
d d d d d d d d d d d
probably responsible for the transport of the amino acid into the cell?
d d d d d d d d d d d d
A. Passive diffusion through the lipid bilayer
d d d d d
B. Uniporter
C. Transport ATPase d
D. Na+ symporter d
E. Na+antiporter
dANS: D d
3. Amembrane permeable byonly Na+ separatestwo compartments containing
d d d d d d
dNa2SO4,shown as follows: d d
, Electrodes are placed in both compartments, and a voltage is applied (that of compartment A
d d d d d d d d d d d d d d
dis held at 0 mV). What voltage applied to compartment B would resultin no net movement of
d d d d d d d d d d d d d d d d
dNa+ across the membrane separating the compartments?
d d d d d d
–60 mV
A. d
–30 mV
B. d
C.
0 mV d
D. +30 mV d
E. +60mV
ANS: E d d
4. Therestingmembrane potentNial oRf a Ic ellGis –B
d 85.mCV. Theintracellularand d d d d d d d d
extracellular concentrations of U
d
SN ions are indicated in the following table, as is
several d d d
d d
d d d d d d d d d
the calculated
d d
Nernst equilibrium potential (Ei) for each of these ions:
d d d d d d d d
Ion Concentration Concentration Ei
Inside Cell d Outside Cell d
+
Na 12 mEq/L d 145 mEq/L d 66 mV d
K+ 150 mEq/L d 4 mEq/L d –96 mV d
Cl– 30 mEq/L d 105 mEq/L d –33 mV d
Ca++ 0.0001 mmol/dL d 1 mmol/dL d 122 mV d
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
d d d d d d d d d d d d d
dmembrane is the greatest for which ion?
d d d d d d
A. Na+
B. K+
C. Cl–
D. Ca++
ANS d
:
B
5. A cell contains the following membrane transporters:
d d d d d d
Na+channelK+channel
d d
Na+,K+-ATPase
d
The resting membrane voltage of the cell is –80 mV, and the intracellular and
d d d d d d d d d d d d d
, extracellular ion concentrations are as follows:
d d d d d
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L d 145 mEq/L d
K+ 120 mEq/L d 4 mEq/L d
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug on the
d d d d d d d d d d d d d d d d d d d
dfollowing parameters?
d
Intracellular [Na+] d Intracellular [K+] d Cell Volume
d Membrane Voltage d
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
d
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B
6. Which of the labeled proteins (shaded) is attached to the membrane by a
d d d d d d d d d d d d
glycosylphosphatidylinositol (GPI) anchor?
d d d
ANS: E
7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting membrane
d d d d d d d d
d
d d d d d d
potential is –60 mV (cell interior negative). The intracellular and extracellular
d d d d d d d d d d d
concentrations for these ions, as well as the calculated Nernst potentials, are listed
d d d d d d d d d d d d d
as follows:
d d
d d d d d d d
, Koeppen: Berne and Levy Physiology, 7th Edition
d d d d d d
Chapter 01: Principles of Cell
d d d d
FunctionTest Bank
d d
Multiple Choice d
1. The subcellular structure that degrades proteins is called the:
d d d d d d d d
A. Tight junction d
B. Mitochondria
C. Lysosome
D. Plasma membrane d
E. Ribosome
ANS: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The following
d d d d d d d d d d d d d d d d
ddata are obtained: d d
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents the
d d d d d d d d d d d d d d d d d
cell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell is
d d d d d d d d d d d d d d d
markedly reduced. According to this information, which of the followingmechanisms is
d d d d d d d d d d d
probably responsible for the transport of the amino acid into the cell?
d d d d d d d d d d d d
A. Passive diffusion through the lipid bilayer
d d d d d
B. Uniporter
C. Transport ATPase d
D. Na+ symporter d
E. Na+antiporter
dANS: D d
3. Amembrane permeable byonly Na+ separatestwo compartments containing
d d d d d d
dNa2SO4,shown as follows: d d
, Electrodes are placed in both compartments, and a voltage is applied (that of compartment A
d d d d d d d d d d d d d d
dis held at 0 mV). What voltage applied to compartment B would resultin no net movement of
d d d d d d d d d d d d d d d d
dNa+ across the membrane separating the compartments?
d d d d d d
–60 mV
A. d
–30 mV
B. d
C.
0 mV d
D. +30 mV d
E. +60mV
ANS: E d d
4. Therestingmembrane potentNial oRf a Ic ellGis –B
d 85.mCV. Theintracellularand d d d d d d d d
extracellular concentrations of U
d
SN ions are indicated in the following table, as is
several d d d
d d
d d d d d d d d d
the calculated
d d
Nernst equilibrium potential (Ei) for each of these ions:
d d d d d d d d
Ion Concentration Concentration Ei
Inside Cell d Outside Cell d
+
Na 12 mEq/L d 145 mEq/L d 66 mV d
K+ 150 mEq/L d 4 mEq/L d –96 mV d
Cl– 30 mEq/L d 105 mEq/L d –33 mV d
Ca++ 0.0001 mmol/dL d 1 mmol/dL d 122 mV d
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
d d d d d d d d d d d d d
dmembrane is the greatest for which ion?
d d d d d d
A. Na+
B. K+
C. Cl–
D. Ca++
ANS d
:
B
5. A cell contains the following membrane transporters:
d d d d d d
Na+channelK+channel
d d
Na+,K+-ATPase
d
The resting membrane voltage of the cell is –80 mV, and the intracellular and
d d d d d d d d d d d d d
, extracellular ion concentrations are as follows:
d d d d d
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L d 145 mEq/L d
K+ 120 mEq/L d 4 mEq/L d
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug on the
d d d d d d d d d d d d d d d d d d d
dfollowing parameters?
d
Intracellular [Na+] d Intracellular [K+] d Cell Volume
d Membrane Voltage d
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
d
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B
6. Which of the labeled proteins (shaded) is attached to the membrane by a
d d d d d d d d d d d d
glycosylphosphatidylinositol (GPI) anchor?
d d d
ANS: E
7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting membrane
d d d d d d d d
d
d d d d d d
potential is –60 mV (cell interior negative). The intracellular and extracellular
d d d d d d d d d d d
concentrations for these ions, as well as the calculated Nernst potentials, are listed
d d d d d d d d d d d d d
as follows:
d d
