x x x x x x x x x 1
Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
x x x x x x x x
Clayton’sBasicPharmacologyforNurses,19thEdition
x x x x x x x
MULTIPLECHOICE x
1. Whichnameidentifies adruglisted bythe USFood and Drug
x x x x x x x x x x x
Administration (FDA)?
x x
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C x
The official name is the name under which a drug is listed by the
x x x x x x x x x x x x x
FDA. The brand name, or trademark, is the name given to a drug
x x x x x x x x x x x x x
by its manufacturer. The nonproprietary, or generic, name is
x x x x x x x x x
provided by the United States Adopted Names Council.
x x x x x x x x
DIF: CognitiveLevel:Knowledge REF: p. 9 x x x x
OBJ: 1NAT: NCLEXClient Needs Category: Safe, Effective Care x x x x x x x x
Environment TOP: Nursing Process Step: Assessment
x CON: x x x x x
Patient Education
x x
2. Whichsourcecontainsinformation specificto nutritional supplements?
x x x x x x x
a. USPDictionaryofUSAN &International DrugNames x x x x x x x
b. NaturalMedicinesComprehensiveDatabase x x x
c. UnitedStatesPharmacopoeia/NationalFormulary(USPNF) x x x x x
d. DrugInteractionFacts x x
ANS: C x
UnitedStatesPharmacopoeia/NationalFormularycontainsinformationspecifictonutritional
x x x x x x x x
supplements. USP Dictionary of USAN &International Drug Names is a compilation of drug
x x x x x x x x x x x x x x
names, pronunciation guide, and possible future FDA approved drugs; it does not include
x x x x x x x x x x x x x
nutritional supplements. Natural Medicines Comprehensive Database contains
x x x x x x x
evidence-basedinformationonherbalmedicinesandherbalcombinationproducts;itdoesnot x x x x x x x x x x x
include information specific to nutritional supplements. Drug Interaction Facts contains
x x x x x x x x x x
comprehensive information on drug interaction facts; it does not include nutritional supplements.
x x x x x x x x x x x x
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 x x x x x
NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x
TOP: NursingProcessStep: Assessment
x CON: Nutrition |Patient Education x x x x x x x
3. Whichdrugreference contains drugmonographs thatdescribe all drugs ina therapeutic class?
x x x x x x x x x x x x x
a. DrugFactsandComparisons x x x
TestBank ForClayton’s BasicPharmacology forNurses 19thEdition
x x x x x x x x x
,TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
x x x x x x x x x 2
b. DrugInteractionFacts x x
c. HandbookonInjectable Drugs x x x
d. Martindale—TheCompleteDrugReference x x x
ANS: A x
Drug Facts and Comparisons contains drug monographs that describe all drugs in a
x x x x x x x x x x x x
therapeuticclass.Monographsareformattedastablestoallowcomparison ofsimilar
x x x x x x x x x x x x
products, brand names, manufacturers, cost indices, and available dosage forms Online
x x x x x x x x x x x
version is available.
x x x
DIF: CognitiveLevel: Knowledge REF: p. 4Table 1.2 x x x x x x
OBJ: 3 x NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
x x x x x x x
TOP: NursingProcessStep: Assessment
x CON: Safety|Patient Education |ClinicalJudgment x x x x x x x x x x
4. Whichdrugreference contains monographs about virtuallyeverysingle-entitydrugavailable in the
x x x x x x x x x x x x
United States and describes therapeutic uses of drugs, including approved and unapproved uses?
x x x x x x x x x x x x x
a. Martindale:TheCompleteDrugReference x x x x
b. AHFSDrugInformation x x
c. DrugReference x
d. DrugFactsandComparisons x x x
ANS: B x
AHFS Drug Information contains monographs about virtually every single-entity drug availablein
x x x x x x x x x x x
theUnitedStatesanddescribes therapeuticusesofdrugs, includingapproved and unapproved uses.
x x x x x x x x x x x x x x
DIF: CognitiveLevel: Knowledge REF: p. 4Table 1.2 x x x x x x
OBJ: 3 x NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
x x x x x x x
TOP: NursingProcess Step: Planning
x CON: Safety|Patient Education |ClinicalJudgment x x x x x x x x x x
5. Which online drug reference makes available to healthcare providers and the public a standard,
x x x x x x x x x x x x x
comprehensive, up-to-datelookupanddownloadableresourceaboutmedicines?
x x x x x x x x x
a. AmericanDrugIndex x x
b. AmericanHospitalFormulary x x
c. DailyMed
d. DrugReference x
ANS: C x
DailyMedmakes availabletohealthcareproviders and thepublicastandard,comprehensive, up-
x x x x x x x x x x x x
to-datelookupanddownloadableresourceabout medicines.TheAmericanDrugIndexis not
x x x x x x x x x x x x x
appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
x x x x x x x x x x x x x x
The drug reference is not appropriate for patient use.
x x x x x x x x x
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 x x x x x x x OBJ:3 x
NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x
TOP: NursingProcessStep: Implementation
x x x x
CON: Safety|PatientEducation |ClinicalJudgment
x x x x x x x
6. WhichlegislationauthorizestheFDAto determinethesafetyof adrugbeforeitsmarketing?
x x x x x x x x x x x x x x
a. FederalFood,Drug,and CosmeticAct(1938) x x x x x x
b. DurhamHumphreyAmendment (1952) x x x
TestBank ForClayton’s BasicPharmacology forNurses 19thEdition
x x x x x x x x x x
,TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
x x x x x x x x x 3
c. ControlledSubstancesAct(1970) x x x
d. KefauverHarrisDrugAmendment(1962) x x x x
ANS: A x
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of all
x x x x x x x x x x x x x x x x x
drugs before marketing. Later amendments and acts helped tighten FDA control and ensure drug
x x x x x x x x x x x x x x
safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used safely
x x x x x x x x x x x x x x x
without medical supervision and restricts their sale to prescription by a licensedpractitioner.The
x x x x x x x x x x x x x x
ControlledSubstancesActaddressesonlycontrolledsubstancesand theircategorization. The
x x x x x x x x x x x
Kefauver HarrisDrug Amendmentensures drug efficacyand greater drug safety. Drug
x x x x x x x x x x x x
manufacturers are required to prove to the FDA the effectiveness of their products before marketing
x x x x x x x x x x x x x x x
them.
x
DIF: CognitiveLevel: Knowledge REF: p. 5Table l.3 x x x x x x
OBJ: 5 x NAT:NCLEXClient NeedsCategory: Physiological Integrity x x x x x x
TOP: Nursing Process Step: Assessment
x x x x x
CON: Safety|Patient Education |Evidence |Health Care Law
x x x x x x x x x x
7. Whichclassificationdoesmeperidine(Demerol)fallunder?
x x x x x x
a. I
b. II
c. III
d. IV
ANS: B x
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe
x x x x x x x x x x x x x x x x x x
psychological and physicaldependence.ScheduleIdrugs havehigh potentialforabuse and no
x x x x x x x x x x x x x x
recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low to
x x x x x x x x x x x x x x x x x
moderate physical dependence or high psychological dependence. Schedule IV drugs have low
x x x x x x x x x x x x
potential for abuse. Use may lead to limited physical or psychological dependence.
x x x x x x x x x x x x
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ:2 x x x x x
NAT: NCLEXClient NeedsCategory: Safe,EffectiveCareEnvironment
x x x x x x x x x
TOP: NursingProcessStep: Assessment
x CON: Patient Education |Addiction|Pain x x x x x x x x x
8. Whichaction wouldtheFDAtaketoexpeditedrugdevelopment and approvalforan outbreak of
x x x x x x x x x x x x x x x
smallpox?
x
a. Listsmallpox asahealth orphandisease.x x x x x x
b. Omitthepreclinical researchphase. x x x x
c. Extendtheclinicalresearchphase. x x x x
d. Fasttracktheinvestigationaldrug. x x x x
ANS: D x
Once the Investigational New Drug Application has been approved, the drug can receive highest
x x x x x x x x x x x x x
priority within the agency, which is called fast tracking. A smallpox outbreak would become a
x x x x x x x x x x x x x x x
priority concern in the world. Orphan diseases are not researched in a priority manner. Preclinical
x x x x x x x x x x x x x x x
research is not omitted. Extending anyphase of the research would mean alongertimeto develop a
x x x x x x x x x x x x x x x x x x
vaccine.TheFDAmust ensurethatall phasesof thepreclinical and clinical research phase have been
x x x x x x x x x x x x x x x x x
completed in a safe manner.
x x x x x
DIF: CognitiveLevel: Knowledge x x REF: p. 7 x x x OBJ: 5 x
TestBank ForClayton’s BasicPharmacology forNurses 19thEdition
x x x x x x x x x x
, TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
x x x x x x x x x 4
NAT: NCLEX Client Needs Category:Safe, Effective Care Environment
x x x x x x x x
TOP: Nursing Process Step: Assessment
x x x x x
CON: HealthCareLaw|Health CarePolicy |Infection |CareCoordination
x x x x x x x x x x x x
9. Whichstatement is trueabout over-the-counter(OTC) drugs?
x x x x x x x
a. Theyare not listed in theUSPNF. x x x x x x x
b. Aprescription froma healthcareprovideris needed.
x x x x x x x
c. Theyaresoldwithoutaprescription. x x x x x
d. Theyareknown onlybytheir brand names. x x x x x x x
ANS: C x
OTC medications do not require a prescription. A variety of names, both generic and trade, canbe
x x x x x x x x x x x x x x x x
used forindividualdrugssold OTC.OTC drugsarelistedintheUSPNF. Prescription drugs require an
x x x x x x x x x x x x x x x x x x
order by a health professional who is licensed to prescribe, such as a physician, nurse practitioner,
x x x x x x x x x x x x x x x x
physician assistant, or dentist.
x x x x
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ:2 x x x x x
NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x
TOP: NursingProcess Step: Planning
x CON: PatientEducation x x x x x
10. Whichisthemost authoritativereferenceformedicationsthatareinjected?
x x x x x x x x x x
a. Martindale:TheComplete x x
b. HandbookonInjectable Drugs x x x
c. DailyMed
d. HandbookofNonprescriptionDrugs x x x
ANS: B x
The Handbook on Injectable Drugs is the most comprehensive reference available on the topicof
x x x x x x x x x x x x x x
compatibilityofinjectabledrugs. Itisacollection ofmonographs formorethan300 injectable drugs
x x x x x x x x x x x x x x x x
that are listed alphabetically by generic name.
x x x x x x x
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 x x x x x
NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x
TOP: NursingProcessStep: Assessment
x CON: ClinicalJudgment |Safety x x x x x x x
11. Whichstatementistrueabout Lomotil? x x x x x
a. Abusepotential forthisdrugis low. x x x x x x
b. Psychologicaldependencyislikely. x x x
c. Thereis ahigh potential forabuse. x x x x x x
d. This drugis not acontrolled substance. x x x x x x
ANS: A x
Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological dependence
x x x x x x x x x x x x x x
liabilitycomparedwithdrugsinSchedule IV. Becauseabusepotentialislow with aSchedule Vdrug, a
x x x x x x x x x x x x x x x x x x
prescription maynot be required. Psychological dependencyisnot likely with a Schedule V drug.
x x x x x x x x x x x x x x x
Schedule V drugs are classified as controlled substances.
x x x x x x x x
DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ:2 x x x x x x x
NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x
TOP: NursingProcessStep: Assessment
x CON: ClinicalJudgment |Safety |PatientEducation x x x x x x x x x x