NSG 533 Advanced Pharmacology Test 1 Week 4
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Which of the following C
SSRIs requires up to a 5-
week washout period
because of the
long half-life of its potent
active metabolite?
A. Escitalopram
B. Fluvoxamine
C. Fluoxetine
D. Sertraline
Which of the following D
symptoms is most likely to
improve within
approximately 1 week
of starting treatment?
A. Depressed mood
B. Suicidal thoughts
C. Anhedonia
D. Sleep
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Of the following B
combinations of
medications, which one
would you want to avoid?
A. Fluoxetine-lithium
B. Fluoxetine-phenelzine
C. Citalopram-valproic
acid
D. Citalopram-aripiprazole
A 26-year-old man with a D
history of depression has
been taking sertraline 200
mg/day for 12 weeks with
no response. The patient
has no other
complications. The
physician asks for your
recommendation. The
most reasonable
recommendation would
be to:
A. Increase sertraline
B. Add fluoxetine
C. Switch to amitriptyline
D. Change to venlafaxine
E. Decrease sertraline
Which of the following is a C
dangerous combination?
A. MAOI-lorazepam
B. MAOI-acetaminophen
C. MAOI-meperidine
D. MAOI-ziprasidone
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A 23-year-old married B
white woman comes to
the outpatient psychiatric
clinic
complaining of decreased
sleep, decreased appetite,
decreased concentration,
depressed
mood, thoughts of death,
and lack of interest in
activities for 6 weeks'
duration. She has
no history of psychiatric
illness and takes no
medications except for
Ortho-Tri Cyclen Lo
daily. Based upon the
patients symptoms,
choose the best
medication to treat this
patient.
A. Nefazodone 100 mg po
twice daily
B. Paroxetine 20 mg po
daily
C. St. John's wort 300 mg
po three times daily
D. Amitriptyline 25 mg at
bedtime
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A 36-year-old man is D
admitted to the hospital
for a severe methicillin-
resistant Staphylococcus
aureus diabetic foot
infection and is started on
linezolid 600 mg IV every
12 hours. His medication
profile includes
paroxetine 40 mg every
morning, trazodone 100
mg at bedtime as needed
for sleep, and metformin
1000 mg po twice daily.
After 3
days on these
medications, the patient
becomes agitated,
confused, and diaphoretic
and develops myoclonic
jerks. Which of the
following is the most likely
diagnosis?
A. Overdose of metformin
B. Bacterial meningitis
C. Neuroleptic malignant
syndrome
D. Serotonin syndrome
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