Advanced Pathophysiology: Exam 1, Regis College NU606
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Terms in this set (236)
Chapter 1: Introduction to
Pathophysiology
Factor that when present increases the chance of disease
Risk Not stressors, but conditions or situations that increase the likelihood of
encountering a stressor
A measure of disease that allows us to determine a person's likelihood of having a
disease. Therefore, the number of prevalent cases is the total number of cases of
Prevalence disease existing in a population. A prevalence rate is the total number of cases of a
disease existing in a population divided by the total population
Indicates how widespread the disease is
A measure of disease that allows us to determine a person's probability of being
diagnosed with a disease during a given period of time. Therefore, incidence is the
Incidence number of newly diagnosed cases of a disease. An incidence rate is the number of
new cases of a disease divided by the number of persons at risk for the disease.
Conveys information about the risk of contracting the disease.
The quantitative relation between two amounts showing the number of times one
Ratio
value contains or is contained within the other.
Altering susceptibility or reducing exposure for susceptible persons
*Both illness and disease are absent
Primary Prevention
example: vaccinations, healthy lifestyles
, Early detection, screening, and management of disease
*Illness absent, disease present
Secondary Prevention
example: screenings and testings
Rehabilitation, supportive care, reducing disability, and restoring effective
functioning
Tertiary Prevention *Both illness and disease present
example: education
study of the patterns of disease involving populations; examining the occurrence,
Epidemiology incidence, prevalence, transmission, and distribution of diseases in large groups of
populations/people
Endemic A disease theat is native to a local region
When a disease is disseninated to many individals at the same time
Epidemic
(spread to many people at the same time)
Epidemics that affect large geographic regions, perhaps spreading worldwide.
Pandemic
(spread to large geographic areas)
Chapter 2: Homeostasis and Adaptive
Responses to Stressors
A state of being in which all systems are in balance around a articular ideal "set-
Homeostasis
point"
Point where body can no longer return to homeostasis following a prolonged
Exhausation
exposure to noxious agents
"Cost" of body's organs and tissues for an excessive or ineffectively regulated
Allostatic Overload
allostatic response; effect of "wear and tear" on the body
Adaptation: biopsychosocial process of change in response to new or altered
circumstances, internal or external in origin
Adaptation Coping: behavioral adaptive response to a stressor using culturally based coping
mechanisms
Adaptation and coping: terms used interchangeably
Includes alterations in responsiveness to homeostatic pressures, sensory stimuli and
Arousal
emotional reactivity, and to changes in motor activity
Primary glucocorticoid
Affects protein metabolism
Promotes appetite and food-seeking behaviors
Has anti-inflammatory effects
Function of Cortisol
Chemical mediator in the inflammation response of the body
Adrenal corticosteroid critical to maintenance of homeostasis
May synergize or antagonize effects of catecholamines
Chapter 3: Cell Structure and Function
Hormones traveling in the bloodstream
Endocrine Communication
Long range signaling
Neurons firing information through synapses
Neurocrine Communication
Signals travel a very small distance between neuron and target cell
Signaling through the extraceullar fluid between cells in a tissue
Paracrine Communcation
Localized areas of communication