NR 508 Advanced Pharmacology Week 3 Quiz 2025|
Chamberlain University| Actual Exam Questions and
Correct Answers
Ranolazine is used in angina patients to:
A) Increase myocardial oxygen supply
B) Reduce myocardial oxygen demand
C) Prevent platelet aggregation
D) Dilate coronary arteries
Correct Answer: B) Reduce myocardial oxygen demand
Explanation: Ranolazine reduces myocardial oxygen demand by inhibiting late sodium currents
in cardiac cells, decreasing myocardial workload and improving angina symptoms without
significantly affecting heart rate or blood pressure.
Antacids treat gastroesophageal reflux disease by:
A) Inhibiting proton pump activity
B) Neutralizing gastric acid
C) Enhancing esophageal motility
D) Coating the stomach lining
Correct Answer: B) Neutralizing gastric acid
Explanation: Antacids work by neutralizing gastric acid, reducing the acidity of stomach
contents that reflux into the esophagus, thereby alleviating GERD symptoms.
Your patient has type 2 diabetes and a high triglyceride level. She has gemfibrozil prescribed to
treat her hypertriglyceridemia. A history of which of the following might contraindicate the use
of this drug?
A) Hypertension
B) Gallbladder disease
C) Asthma
D) Hypothyroidism
Correct Answer: B) Gallbladder disease
Explanation: Gemfibrozil, a fibrate, is contraindicated in patients with gallbladder disease due
to an increased risk of gallstone formation, a known adverse effect of fibrates.
, Joanne is a 60-year-old patient with an LDL of 132 mg/dL and a family history of coronary
artery disease. She has tried diet changes (increased fiber and plant sterols) for 6 months without
reaching her LDL goal. The next step in her treatment would be:
A) Initiate a statin
B) Add ezetimibe immediately
C) Increase dietary fiber intake further
D) Prescribe niacin
Correct Answer: A) Initiate a statin
Explanation: Statins are the first-line therapy for LDL reduction in patients with elevated
cardiovascular risk, such as those with a family history of coronary artery disease, when lifestyle
changes are insufficient.
Combining a fibric acid derivative such as gemfibrozil with which of the following is not
recommended?
A) Statins – Increased risk of myopathy
B) Niacin – Increased risk of hepatotoxicity
C) Bile acid sequestrants – Reduced absorption of gemfibrozil
D) Ezetimibe – Increased gastrointestinal side effects
Correct Answer: A) Statins – Increased risk of myopathy
Explanation: Combining gemfibrozil with statins increases the risk of myopathy and
rhabdomyolysis due to pharmacokinetic interactions that elevate statin levels, making this
combination generally avoided.
Amiodarone has been prescribed for a patient with a supraventricular dysrhythmia. Patient
teaching should include all of the following EXCEPT:
A) Report symptoms of thyroid dysfunction
B) Avoid grapefruit juice
C) Monitor for signs of pulmonary toxicity
D) Take the medication with a high-fat meal
Correct Answer: D) Take the medication with a high-fat meal
Explanation: Amiodarone does not require a high-fat meal for absorption. Patients should be
educated about monitoring for thyroid dysfunction, pulmonary toxicity, and avoiding grapefruit
juice due to drug interactions.
If a patient with gastroesophageal reflux disease taking a proton pump inhibitor daily is not
improving, the plan of care would be:
Chamberlain University| Actual Exam Questions and
Correct Answers
Ranolazine is used in angina patients to:
A) Increase myocardial oxygen supply
B) Reduce myocardial oxygen demand
C) Prevent platelet aggregation
D) Dilate coronary arteries
Correct Answer: B) Reduce myocardial oxygen demand
Explanation: Ranolazine reduces myocardial oxygen demand by inhibiting late sodium currents
in cardiac cells, decreasing myocardial workload and improving angina symptoms without
significantly affecting heart rate or blood pressure.
Antacids treat gastroesophageal reflux disease by:
A) Inhibiting proton pump activity
B) Neutralizing gastric acid
C) Enhancing esophageal motility
D) Coating the stomach lining
Correct Answer: B) Neutralizing gastric acid
Explanation: Antacids work by neutralizing gastric acid, reducing the acidity of stomach
contents that reflux into the esophagus, thereby alleviating GERD symptoms.
Your patient has type 2 diabetes and a high triglyceride level. She has gemfibrozil prescribed to
treat her hypertriglyceridemia. A history of which of the following might contraindicate the use
of this drug?
A) Hypertension
B) Gallbladder disease
C) Asthma
D) Hypothyroidism
Correct Answer: B) Gallbladder disease
Explanation: Gemfibrozil, a fibrate, is contraindicated in patients with gallbladder disease due
to an increased risk of gallstone formation, a known adverse effect of fibrates.
, Joanne is a 60-year-old patient with an LDL of 132 mg/dL and a family history of coronary
artery disease. She has tried diet changes (increased fiber and plant sterols) for 6 months without
reaching her LDL goal. The next step in her treatment would be:
A) Initiate a statin
B) Add ezetimibe immediately
C) Increase dietary fiber intake further
D) Prescribe niacin
Correct Answer: A) Initiate a statin
Explanation: Statins are the first-line therapy for LDL reduction in patients with elevated
cardiovascular risk, such as those with a family history of coronary artery disease, when lifestyle
changes are insufficient.
Combining a fibric acid derivative such as gemfibrozil with which of the following is not
recommended?
A) Statins – Increased risk of myopathy
B) Niacin – Increased risk of hepatotoxicity
C) Bile acid sequestrants – Reduced absorption of gemfibrozil
D) Ezetimibe – Increased gastrointestinal side effects
Correct Answer: A) Statins – Increased risk of myopathy
Explanation: Combining gemfibrozil with statins increases the risk of myopathy and
rhabdomyolysis due to pharmacokinetic interactions that elevate statin levels, making this
combination generally avoided.
Amiodarone has been prescribed for a patient with a supraventricular dysrhythmia. Patient
teaching should include all of the following EXCEPT:
A) Report symptoms of thyroid dysfunction
B) Avoid grapefruit juice
C) Monitor for signs of pulmonary toxicity
D) Take the medication with a high-fat meal
Correct Answer: D) Take the medication with a high-fat meal
Explanation: Amiodarone does not require a high-fat meal for absorption. Patients should be
educated about monitoring for thyroid dysfunction, pulmonary toxicity, and avoiding grapefruit
juice due to drug interactions.
If a patient with gastroesophageal reflux disease taking a proton pump inhibitor daily is not
improving, the plan of care would be:
