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, Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the
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expected effect for this prescription? rf rf rf rf



A. Curative effect on symptoms rf rf rf



B. Systemic effect on symptoms rf rf rf



C. Local effect on symptoms rf rf rf



D. Parenteral effect on symptoms rf rf rf




ANS: B r f



Rationale: Drugs that produce systemic effects are taken into the body, circulated through the b
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loodstream to their sites of action in various body tissues, and eventually eliminated from the b
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ody. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride
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will control the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen
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and local anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not admi
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nistered parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or i
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ntravenously.

PTS: 1 REF: p. 3, Introduction OBJ: 1 rf rf



NAT: r f Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
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OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety rf rf rf rf rf rf rf rf



KEY: r f Integrated Process: Nursing Process rf rf rf



BLM: r fCognitive Level: Understand NOT: Multiple Choice rf rf r f rf




2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOtMi s anothername for this type of me
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dication?
A. Synthetic drug rf



B. Semisynthetic drug rf



C. Biotechnology drug rf



D. Prototype drug rf




ANS: B r f



Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
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have been chemically modified. Synthetic drugs are more standardized in their chemical charac
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teristics, more consistent in their effects, and less likely to produce allergic reactions. Biotechn
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ology drugs involve manipulating DNA and RNA and recombining genes into hybrid molecul
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es that can be inserted into living organisms. Prototype drugs are the first drug of a particular gr
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oup to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 rf rf rf



NAT: r f Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
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OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety rf rf rf rf rf rf rf rf



KEY: r f Integrated Process: Nursing Process rf rf rf



BLM: r fCognitive Level: Understand NOT: Multiple Choice rf rf r f rf




3. Which classification applies to morphine?
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A. Central nervous system depressant rf rf rf



B. Central nervous system stimulant rf rf rf




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