Y Y Y
Illustrated Reviews: Pharmacology 8th
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Edition by Karen Whalen
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COMPLETE CHAPTERS 1- Y Y
48 WITH RATIONALES|A+ GRADED
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100% EXPERT VERIFIED Q&As
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, 3. TheYnurseYisYteachingYaYpatientYwhoYwillYbeYdischargedYhomeYwithYaYprescriptionYforYanYenteric-
YcoatedY
tablet.YWhichYstatementYbyYtheYpatientYindicatesYunderstandingYofYtheYteaching?
a. IYmayYcrushYtheYtabletYandYputYitYinYapplesauceYtoYimproveYabsorption.
b. IYshouldYconsumeYacidicYfoodsYtoYenhanceYabsorptionYofYthisYmedication.
c. IYshouldYexpectYaYdelayYinYonsetYofYtheYdrugsYeffectsYafterYtakingYtheYtablet.
d. IYshouldYtakeYthisYmedicationYwithYhigh-fatYfoodsYtoYimproveYitsYaction.YCORRECTYANSWER:YC
Enteric-
coatedYtabletsYresistYdisintegrationYinYtheYacidicYenvironmentYofYtheYstomachYandYdisintegrateYwhenYtheyY
reachYtheYsmallYintestine.YThereYisYusuallyYsomeYdelayYinYonsetYofYactionsYafterYtakingYtheseYmedications
.YEnteric-
coatedYtabletsYshouldYnotYbeYcrushedYorYchewed,YwhichYwouldYalterYtheYtimeYandYlocationYofYabsorption.
YAcidicYfoodsYwillYnotYenhanceYtheYabsorptionYofYtheYmedication.YTheYpatientYshouldY notYtoYeatYhigh-
fatYfoodYbeforeYingestingYanYenteric-coatedYtablet,YbecauseYhigh-fatYfoodsYdecreaseYtheYabsorptionYrate.
DIF:YCOGNITIVEYLEVEL:YApplyingY(Application)YREF:YdmY3YTOP:YNURSINGYPROCESS:YNursingYI
ntervention
MSC:YNCLEX:YPhysiologicalYIntegrity:YPharmacologicalYandYParenteralYTherapies
4. AYpatientYwhoYisYnewlyYdiagnosedYwithYtypeY1YdiabetesYmellitusYasksYwhyYinsulinYmustYbeYgiven
YbyYsubcutaneousYinjectionYinsteadYofYbyYmouth.YTheYnurseYwillYexplainYthatYthisYisYbecause
a. absorptionYisYdiminishedYbyYtheYfirst-passYeffectsYinYtheYliver.
b. absorptionYisYfasterYwhenYinsulinYisYgivenYsubcutaneously.
c. digestiveYenzymesYinYtheYgastrointestinalYtractYpreventYabsorption.
d. theYoralYformYisYlessYpredictableYwithYmoreYadverseYeffects.YCORRECTYANSWER:YC
Insulin,YgrowthYhormones,YandYotherYprotein-
basedYdrugsYareYdestroyedYinYtheYsmallYintestineYbyYdigestiveYenzymesYandYmustYbeYgivenYparenterally.Y
BecauseYinsulinYisYdestroyedYbyYdigestiveYenzymes,YitYwouldYnotYmakeYitYtoYtheYliverYforYmetabolismYwit
hYaYfirst-
passYeffect.YSubcutaneousYtissueYhasYfewerYbloodYvessels,YsoYabsorptionYisYslowerYinYsuchYtissue.YInsuli
nYisYgivenYsubcutaneouslyYbecauseYitYisYdesirableYtoYhaveYitYabsorbYslowly.
DIF:YCOGNITIVEYLEVEL:YUnderstandingY(Comprehension)YREF:YdmY3YTOP:YNURSINGYPROCESS:Y
NursingYIntervention:YPatientYTeaching
MSC:YNCLEX:YPhysiologicalYIntegrity:YPharmacologicalYandYParenteralYTherapies
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