Rodak's Hematology: Clinical Principles and Applications
Author: Elaine M. Keohane
7th Edition
,Table of contents
Part I: Introduction to Hematology
1. An Overview of Clinical Laboratory Hematology
2. Quality Assurance in Hematology and Hemostasis Testing
Part II: Blood Cell Production, Structure, and Function
3. Cellular Structure and Function
4. Hematopoiesis
5. Erythrocyte Production and Destruction
6. Erythrocyte Metabolism and Membrane Structure and Function
7. Hemoglobin Metabolism
8. Iron Kinetics and Laboratory Assessment
9. Leukocyte Development, Kinetics, and Functions
10. Platelet Production, Structure, and Function
Part III: Laboratory Evaluation of Blood Cells
11. Manual, Semiautomated, and Point-of-Care Testing and Hematology
12. Automated Blood Cell Analysis
13. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count
14. Bone Marrow Examination
15. Body Fluid Analysis in the Hematology Laboratory
Part IV: Erythrocyte Disorders
16. Anemias: Red Blood Cell Morphology and Approach to Diagnosis
17. Disorders of Iron Kinetics and Heme Metabolism
18. Anemias Caused by Defects of DNA Metabolism
19. Bone Marrow Failure
20. Introduction to Increased Destruction of Erythrocytes
21. Intrinsic Defects Leading to Increased Erythrocyte Destruction
22. Extrinsic Defects Leading to Increased Erythrocyte Destruction-- Nonimmune Causes
23. Extrinsic Defects Leading to Increased Erythrocyte Destruction-- Immune Causes
24. Hemoglobinopathies (Structural Defects in Hemoglobin)
25. Thalassemias
Part V: Leukocyte Disorders
26. Non-Malignant Leukocyte Disorders
27. Intro to Hematologic Malignancies
28. Flow Cytometric Analysis in Hematologic Disorders
29. Molecular Diagnostics in the Clinical Laboratory
,30. Cytogenetics
31. Acute Leukemias
32. Myeloproliferative Neoplasms
33. Myelodysplastic Syndromes
34. Mature Lymphoid Neoplasms
Part VI: Hemostasis and Thrombosis
35. Normal Hemostasis and Coagulation
36. Hemorrhagic Disorders and Laboratory Assessment
37. Qualitative Disorders of Platelets and Vasculature
38. Thrombocytopenia and Thrombocytosis
39. Thrombotic Disorders and Laboratory Assessment
40. Antithrombotic Therapies and Their Laboratory Assessment
41. Laboratory Evaluation of Hemostasis
42. Hemostasis and Coagulation Instrumentation
Part VII: Hematology and Hemostasis in Selected Populations
43. Hematology and Hemostasis in the Pediatric, Geriatric, and Pregnant Populations
, 1. Chapter 01-01 Hematology Is The Study Of:
* A. Blood Cells.
b. Serum Electrolytes.
c. Plasma Hormone Levels.
d. Bacteria In The Blood.
General Feedback:
Hematology Is The Study Of Blood Cells—Red Blood Cells, White Blood Cells, And Platelets. Plasma
And Serum Electrolytes And Hormone Levels Are Evaluated In Various Subdivisions Of Clinical
Chemistry, And Bacteria Are Evaluated In Clinical Microbiology.
2. Chapter 01-02
The Morphology Of Blood Cells Is Important To Evaluate:
a. Every Time A Complete Blood Count (CBC) Is Requested On A Patient.
b. When An Instrument-Generated Flag Is Obtained.
* C. When A Profiling Instrument Result Is Abnormal.
D. When The White Count Is Elevated.
General Feedback:
Every Laboratory Must Determine—Based On Its Instrumentation, Needs Of The Clinician And Other
Parameter Flags That Alert The Medical Laboratory Scientist To The Necessity For Further Evaluation—
When It Is Necessary To Evaluate Cell Morphology. Many Instrument-Generated Flags, Although
Useful, May Not Require Review. If An Automated CBC Does Not Suggest The Need, No Reason Exists
To Evaluate The Blood Film, Even If The White Count Is Elevated.
3. Chapter 01-03
Who Is Ultimately Responsible For Determining The Specimen Integrity Before Analysis?
* A. Medical Laboratory Professional
b. Nursing Staff
c. Phlebotomist
d. Specimen-Processing Personnel
General Feedback:
The Medical Laboratory Scientist Is Responsible For Ensuring The Integrity Of A Specimen Before
Analysis. Only He Or She Can Judge Whether The Specimen Is Acceptable So That Valid Results Can Be
Obtained. Acceptable Criteria Include Such Things As Type Of Specimen For The Test Ordered (E.G.,
Blood, Serum, Urine); Appropriate Additive Present (If Needed) And Amount Of Specimen Relative To
The Additive; Time Interval Since Obtained; And Presence Or Absence Of Hemolysis, Lipemia, And
Other Similar Conditions. None Of The Other Personnel Named Have The Education And
Understanding To Fully Make That Judgment.