Test Bank – Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (North American) | Geralyn Frandsen & Sandra Pennington | Correct Verified Answers | Updated 2025

ABRAM’S CLINICAL DRUG THERAPY RATIONALES FOR
NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
TESTBANK/COMPLETE GUIDE 2024-2025/ALL CHAPTERS 1-61

,Chapter 1: The Foundation of Pharmacology: Quality and Safety
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1. A patient diagnosed with obsessive–compulsive disorder has been prescribed
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oral paroxetine hydrochloride. What is the expected effect for this
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prescription?
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A. Curative effect on symptoms W W W


B. Systemic effect on symptoms W W W


C. Local effect on symptoms W W W


D. Parenteral effect on symptoms W W W




ACCURATE ANSWER:-B W


REASONING:->>>Pharmaceutical drug that produce systemic effects are taken into W W W W W W W W


Wthe body, circulated through the bloodstream to their sites of action in various body
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Wtissues, and eventually eliminated from the body. Curative agents are given to cure a
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Wdisease process. In this case, paroxetine hydrochloride will control the symptoms but
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Wnot cure the disorder.
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Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act
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Wmainly at the site of application. Paroxetine hydrochloride is not administered
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Wparenterally. Parenteral agents are administered subcutaneously, intramuscularly, or
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Wintravenously.

POINTS: 1 REFERENCE: p. 3, Introduction W W OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
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WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
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WQuality and Safety W W


KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
W NOT: Multiple Choice W W W W




2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug
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is a naturally occurring substance that has been cheG
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haOt Mi s W W W W W WW W W


another name for this type of pharmaceutical drug?
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A. Synthetic drug W


B. Semisynthetic drug W


C. Biotechnology drug W


D. Prototype drug W




ACCURATE ANSWER:-B W


REASONING:->>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are W W W W W W


naturally occurring substances that have been chemically modified. Synthetic
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pharmaceutical drug are more standardized in their chemical characteristics, more
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consistent in their effects, and less likely to produce allergic reactions. Biotechnology
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pharmaceutical drug involve manipulating DNA and RNA and recombining genes
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into hybrid molecules that can be inserted into living organisms. Prototype
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pharmaceutical drug are the first drug of a particular group to be developed.
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POINTS: 1 REFERENCE: p. 3, Drug Sources OBJ: 1 W W W


NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
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WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
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WQuality and Safety W W


KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
W NOT: Multiple Choice W W W W




3. Which classification applies to morphine?
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A. Central nervous system depressant W W W


B. Central nervous system stimulant W W W

, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A W


REASONING:->>>Pharmaceutical drug are classified according to their effects on W W W W W W W W


particular body systems, their therapeutic uses, and their chemical characteristics.
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Morphine is classified as a central nervous system depressant and will produce this
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effect in the hospital client. A central nervous system stimulant increases attention and
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raises mood. An anti-inflammatory agent decreases inflammation at the site of tissue or
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joint inflammation. An antihypertensive agent reduces blood pressure.
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POINTS: 1 REFERENCE: p. 3, Drug W W


Classifications and Prototypes OBJ:
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NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
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WParenteral Therapies TOP: W Chapter: 1: The Foundation of Pharmacology:
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WQuality and Safety W W


KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember
W NOT: Multiple Choice
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4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical
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Wdrug belongs to which drug group?
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A. Selective serotonin reuptake inhibitors
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B. Diuretics
C. Penicillins
D. ACE inhibitors W




ACCURATE ANSWER:-C W


REASONING:->>>The generic name often indicates the drug group (e.g., pharmaceutical drug
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with generic names ending in “cillin” are penicillins). Selective serotonin reuptake
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W
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W
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inhibitors are pharmaceutical drugs
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that have antidepressant effects; SSRI is a broad classification, not a generic name.
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WDiuretics are pharmaceutical drugs that increase urine output; diuretic is a broad
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Wclassification, not a generic name. ACE inhibitor is the broad classification for the
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Wangiotensin receptor blockers, not the generic name.
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POINTS: 1 REFERENCE: p. 3, Drug Names OBJ: 2 W W W


NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
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WParenteral Therapies TOP: W Chapter: 1: The Foundation of Pharmacology:
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WQuality and Safety W W


KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
W NOT: Multiple Choice
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5. The administration of diphenhydramine is regulated by which U.S. government agency?
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A. Public Health Service W W


B. Federal Trade Commission W W


C. Occupational Safety and Health Administration W W W W


D. Food and W




WDrug

Administration
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ACCURATE ANSWER:-D W

, REASONING:->>>The Food and Drug Administration approves pharmaceutical drug W W W W W W W


for over- the-counter availability, including the transfer of pharmaceutical drug from
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prescription to OTC status, and may require clinical trials to determine the safety and
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effectiveness of OTC use. The Public Health Service is regulated by the state to
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maintain the health of individual citizens of the state. The Federal Trade Commission
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regulates imports and exports throughout the nation. The Occupational Safety and
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Health Administration regulates safety within the workplace.
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POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription W W W W


Pharmaceutical drug OBJ: 4 W W


NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
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WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
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WQuality and Safety W W


KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
W NOT: Multiple Choice W W W W




6. In W the U.S., the administration of anabolic steroids is regulated by which law?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Comprehensive Drug Abuse Prevention and Control Act
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C. The Harrison Narcotic Act
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D. The Sherley Amendment
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ACCURATE ANSWER:-B W


REASONING:->>>The Comprehensive Drug Abuse Prevention and Control Act W W W W W W W


regulates the manufacture and distribution of narcotics, stimulants, depressants,
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hallucinogens, and anabolic steroids. The Food, Drug, and Cosmetic Act of 1938
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revised and broadened FDA powers and responsibilities, giving the FDA control over
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drug safety. The Harrison Narcotic Act restricted the importation, manufacture, sale,
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and use of opium, cocaine, marijuana, and other pharmaceutical drug that the act d e f i Gn
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eRd AaDs E
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tiO
csS Th.eCSOhM
. T W erley Amendment of 1912 prohibited fraudulent claims of drug
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effectiveness.
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POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription W W W W


Pharmaceutical drug OBJ: 3 W W


NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
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WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
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WQuality and Safety W W


KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember
W NOT: Multiple Choice W W W W




7. A nursing attendant is responsible for maintaining an accurate count and record of
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Wthe controlled substances on the nursing division. This nursing action is regulated
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Wby whichW


U.S. law or agency?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Public Health Service
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C. The Drug Enforcement Administration
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D. The Sherley W




WAmendment ACCURATE W




WANSWER:-C