NU 643 ADVANCED PSYCHOPHARMACOLOGY FINAL
EXAMS (4 VERSIONS) ALL QUESTIONS AND CORRECT
ANSWERS GRADED A+ REGIS COLLEGE/ REGIS NU
643 FINAL EXAM WEEK 15|| LATEST UPDATE 2025/26
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Dopamine (DA)
Role: reward, pleasure, motivation
Production Site: Substantia nigra, Ventral tegmental area (VTA), Hypothalamus
Receptors:D1, D2, D3
Conditions: ADHD, Schizophrenia, Parkinson’s, addiction
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Serotonin (5-HT)
Role: mood, sleep, appetite
Production Site: Raphe nuclei
Receptors: 5-HT1A – 5-HT7 (many in GI tract)
Conditions: increased in OCD and tics, decreased in depression
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Norepinephrine (NE)
Role: arousal, alertness, fight or flight, stress response, mood regulation
,Production Site: Locus coeruleus
Receptors: Alpha and Beta Receptors
Conditions: depression, ADHD, anxiety/panic, mania
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
GABA
Role: calms brain activity, decreases anxiety and excitability, promotes relaxation and
sleep, prevents overstimulation/seizures
Production Site: brain and spinal cord
Receptors: GABA-A & GABA-B
Conditions: decreased GABA in anxiety and seizures
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Glutamate
Role: learning, memory
Production Site: widespread throughout the CNS (especially in the hippocampus and
cortex)
Receptors: NMDA, AMPA, Kainate
Conditions: increased amount causes excitotoxicity seen in stroke, ALS, alcohol w/d
and epilepsy
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Acetylcholine (ACh)
, Role: learning, memory, muscle contraction, attention
Production Site: Cerebral cortex, basal nuclei, nucleus basalis of Meynert
Receptors: Nicotinic and Muscarinic
Conditions: Alzheimer’s = widespread loss of ACh neurons
Anticholinergic side effects (dry mouth, constipation, confusion).
Dopamine Pathway: Name its function and disorder/effects it causes when
dysregulated
Mesocortical
Function: Cognition (judgment, reasoning, insight, motivation).
Disorder: ↓ DA → Negative symptoms of schizophrenia (flat affect, poor motivation).
Dopamine Pathway: Name its function and disorder/effects it causes when
dysregulated
Mesolimbic
Function: Emotions, memory, reward.
Disorder: ↑ DA → Positive symptoms of schizophrenia (hallucinations, delusions).
Dopamine Pathway: Name its function and disorder/effects it causes when
dysregulated
Nigrostriatal
Function: Motor control (voluntary + involuntary).
Disorder: ↓ DA → Parkinson’s, EPS (muscle rigidity, tremor).
Dopamine Pathway: Name its function and disorder/effects it causes when
dysregulated
Tuberoinfundibular
EXAMS (4 VERSIONS) ALL QUESTIONS AND CORRECT
ANSWERS GRADED A+ REGIS COLLEGE/ REGIS NU
643 FINAL EXAM WEEK 15|| LATEST UPDATE 2025/26
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Dopamine (DA)
Role: reward, pleasure, motivation
Production Site: Substantia nigra, Ventral tegmental area (VTA), Hypothalamus
Receptors:D1, D2, D3
Conditions: ADHD, Schizophrenia, Parkinson’s, addiction
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Serotonin (5-HT)
Role: mood, sleep, appetite
Production Site: Raphe nuclei
Receptors: 5-HT1A – 5-HT7 (many in GI tract)
Conditions: increased in OCD and tics, decreased in depression
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Norepinephrine (NE)
Role: arousal, alertness, fight or flight, stress response, mood regulation
,Production Site: Locus coeruleus
Receptors: Alpha and Beta Receptors
Conditions: depression, ADHD, anxiety/panic, mania
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
GABA
Role: calms brain activity, decreases anxiety and excitability, promotes relaxation and
sleep, prevents overstimulation/seizures
Production Site: brain and spinal cord
Receptors: GABA-A & GABA-B
Conditions: decreased GABA in anxiety and seizures
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Glutamate
Role: learning, memory
Production Site: widespread throughout the CNS (especially in the hippocampus and
cortex)
Receptors: NMDA, AMPA, Kainate
Conditions: increased amount causes excitotoxicity seen in stroke, ALS, alcohol w/d
and epilepsy
Neurotransmitters: Name its role, where its produced, receptors, and what
conditions its seen in
Acetylcholine (ACh)
, Role: learning, memory, muscle contraction, attention
Production Site: Cerebral cortex, basal nuclei, nucleus basalis of Meynert
Receptors: Nicotinic and Muscarinic
Conditions: Alzheimer’s = widespread loss of ACh neurons
Anticholinergic side effects (dry mouth, constipation, confusion).
Dopamine Pathway: Name its function and disorder/effects it causes when
dysregulated
Mesocortical
Function: Cognition (judgment, reasoning, insight, motivation).
Disorder: ↓ DA → Negative symptoms of schizophrenia (flat affect, poor motivation).
Dopamine Pathway: Name its function and disorder/effects it causes when
dysregulated
Mesolimbic
Function: Emotions, memory, reward.
Disorder: ↑ DA → Positive symptoms of schizophrenia (hallucinations, delusions).
Dopamine Pathway: Name its function and disorder/effects it causes when
dysregulated
Nigrostriatal
Function: Motor control (voluntary + involuntary).
Disorder: ↓ DA → Parkinson’s, EPS (muscle rigidity, tremor).
Dopamine Pathway: Name its function and disorder/effects it causes when
dysregulated
Tuberoinfundibular
