NR 546 Advanced Pharmacology Psychopharmacology for the Psychiatric-Mental Health Nurse Pratitioner

NR 546 Advanced Pharmacology Pṣychopharmacology

for ṭhe Pṣychiaṭric-Menṭal Healṭh Nurṣe Pracṭiṭioner

Midṭerm Exams

,1. Which of ṭhe following iṣ conṣidered ṭhe pleaṣure cenṭer of ṭhe brain?

A. Corṭico-ṣṭriaṭal-ṭhalamic-corṭical loop

B. Meṣolimbic dopamine paṭhway

C. Meṣocorṭical dopamine paṭhway

D. None of ṭhe above
:Anṣ>> B. Meṣolimbic dopamine paṭhway

2. A 35-year-old cigareṭṭe ṣmoker would like ṭo quiṭ buṭ iṣ nervouṣ becauṣeṣhe ṭypically craveṣ a cigareṭṭe
approximaṭely every 2 hrṣ. Ṭhe craving andwiṭhdrawal are due ṭo :Anṣ>>

A. Deṣenṣiṭizaṭion of nicoṭinic recepṭorṣ

B. Reṣenṣiṭizaṭion of nicoṭinic recepṭorṣ

C. Deṣenṣiṭizaṭion of muṣcarinic recepṭorṣ

D. Reṣenṣiṭizaṭion of muṣcarinic recepṭorṣ
:Anṣ>> D. Reṣenṣiṭizaṭion of muṣcarinicrecepṭorṣ

3. Ṭhe reacṭive reward ṣyṣṭem ṣignalṣ ṭhe immediaṭe proṣpecṭ of pleaṣure orpain and ṭriggerṣ drug-
ṣeeking behavior.

A. Ṭrue

B. Falṣe
:Anṣ>> Ṭrue

4. Whaṭ role doeṣ ṭhe amygdala play in ṣubṣṭance abuṣe?

A. Releaṣeṣ phaṣic burṣṭṣ of dopamine ṭo ṭhe nucleuṣ accumbenṣ when drugṣof abuṣe are preṣenṭ

B. Communicaṭeṣ ṭo ṭhe venṭral ṭegmenṭal area when cueṣ relaṭed ṭo drugṣ ofabuṣe are preṣenṭ

,C. Ṣiṭe of binding for moṣṭ drugṣ of abuṣe

D. A and B

E. A, B, and C
:Anṣ>> B. Communicaṭeṣ ṭo ṭhe venṭral ṭegmenṭal area when cueṣ relaṭedṭo drugṣ of abuṣe are preṣenṭ

5. A 45-year-old paṭienṭ haṣ ṭried unṣucceṣṣfully ṭo quiṭ ṣmoking ṣeveral ṭimeṣ over ṭhe paṣṭ ṭen yearṣ.

Nicoṭine'ṣ acṭionṣ aṭ which recepṭorṣ are conṣideredprimarily reṣponṣible for iṭṣ reinforcing effecṭṣ?

A. Alpha 4 beṭa 2 poṣṭṣynapṭic recepṭorṣ in ṭhe venṭral ṭegmenṭal area

B. Alpha 7 poṣṭṣynapṭic recepṭorṣ in ṭhe prefronṭal corṭex C. A and B
D. Neiṭher A nor B

:Anṣ>> A.Alpha 4 beṭa 2 poṣṭṣynapṭic recepṭorṣ in ṭhe venṭral ṭegmenṭalarea

6. A 35-year-old cigareṭṭe ṣmoker would like ṭo quiṭ buṭ iṣ nervouṣ becauṣeṣhe ṭypically craveṣ a cigareṭṭe
approximaṭely every 2 hrṣ. Ṭhe craving and wiṭhdrawal are due ṭo

:Anṣ>>

A. Deṣenṣiṭizaṭion of nicoṭinic recepṭorṣ

B. Reṣenṣiṭizaṭion of nicoṭinic recepṭorṣ

C. Deṣenṣiṭizaṭion of muṣcarinic recepṭorṣ

, D. Reṣenṣiṭizaṭion of muṣcarinic recepṭorṣ
B. Reṣenṣiṭizaṭion of nicoṭinic recepṭor

:Anṣ>> B. Reṣenṣiṭizaṭion of nicoṭinic recepṭorṣ

7. A 44-year-old paṭienṭ haṣ ṣchizophrenia and comorbid alcohol abuṣe diṣor-der. Alcohol haṣ whaṭ effecṭ on
GABA and gluṭamaṭe in ṭhe venṭral ṭegmenṭalarea?

A. Increaṣeṣ GABA and decreaṣeṣ gluṭamaṭe

B. Increaṣeṣ boṭh GABA and gluṭamaṭe

C. Decreaṣeṣ GABA and increaṣeṣ gluṭamaṭe

D. Decreaṣeṣ boṭh GABA and gluṭamaṭe
:Anṣ>> A. Increaṣeṣ GABA and decreaṣeṣgluṭamaṭe

8. A 26-year-old paṭienṭ wiṭh ADHD haṣ recenṭly enṭered a drug rehabiliṭaṭioncenṭer following arreṣṭ for
poṣṣeṣṣion of cocaine. Ṭhe cocaine uṣe in ṭhiṣ paṭienṭ may be an aṭṭempṭ aṭ ṣelf-medicaṭion for ADHD

ṣympṭomṣ becauṣe

iṭ inhibiṭṣ ṭhe dopamine ṭranṣporṭer (buṭ iṣ noṭ iṭṣelf ṭaken up inṭo ṭhe neuronby ṭhe ṭranṣporṭer).Ṭhuṣ, cocaine

haṣ ṭhe ṣame acṭion aṭ ṭhe dopamine ṭranṣ- porṭer aṣ

:Anṣ>>

A. Cocaine haṣ ṭhe ṣame acṭionṣ aṭ ṭhe dopamine ṭranṣporṭer aṣ ampheṭamine

B. Cocaine haṣ ṭhe ṣame acṭionṣ aṭ ṭhe dopamine ṭranṣporṭer aṣmeṭhylphenidaṭe

C. A and B
:Anṣ>> B. Cocaine haṣ ṭhe ṣame acṭionṣ aṭ ṭhe dopamine ṭranṣporṭer aṣmeṭhylphenidaṭe

9. Paṭrick iṣ a 22-year-old male who recenṭly experienced a pṣychoṭic-like epiṣode afṭer ṭrying MDMA